TECHNIQUES: 313 results

Return to Homepage chemometrics(25)  electrochemistry(32)  instrumentation(37)  mass spectrometry(31)  NMR and EPR(26)  separations(87)  spectroscopy(45)  surfaces/nanomaterials(30)     * editor's choice  Analytical Chemistry 2.0   by David Harvey Details A complete textbook for Quantitative Analysis is freely downloadable. Teach yourself Analytical Chemistry, or be part of a class on the subject. Currently 5.00/5 1 2 3 4 5 Rating: 5.0/5 (2 votes cast) Multiple Regression   by Alan Fielding Details This site provides an introduction to the use of multiple regression, beginning with a glossary of important terms before taking the reader through a review of bivariate regression and the implementation and interpretation of multiple regression. One limitation to the site is its reliance on Minitab for calculations. Users, however, can reproduce the calculations using other software packages, such as SPSS or Excel. Prior knowledge of the basics of bivariate regression is assumed; thus, the site is most appropriate for advanced undergraduates and graduate students. Currently 3.00/5 1 2 3 4 5 Rating: 3.0/5 (1 vote cast) Principal Component Analysis   by Alan Fielding Details This site provides an introduction to principal component analysis, beginning with a glossary of important terms before taking the reader through the process of completing a principal component analysis. One limitation to the site is its reliance on Minitab and SPSS for calculations. Users without access to these programs can reproduce the calculations using other software packages, such as the freeware program R. Prior knowledge of basic statistics is assumed; thus, the site is most appropriate for advanced undergraduates and graduate students. Currently 4.00/5 1 2 3 4 5 Rating: 4.0/5 (1 vote cast) Introduction to Data Analysis   by David Harvey Details Means, standard deviation, and deciding if two results are different at some level of statistical significance is the basis for analytical decision making. This module teaches students how to use t-tests, Q-tests, and to tell when differences are statistically real. Currently 5.00/5 1 2 3 4 5 Rating: 5.0/5 (1 vote cast) The Geometer's Sketchpad - Least Squares   by Java Sketchpad Details This site provides a java-based demonstration of how a least-squares analysis works. The applet opens with a set of data points with a superimposed line. By clicking and dragging, the user can move the data points and change the slope and/or the y-intercept of the line. The residual error for each data point is shown as a square whose area increases the greater the vertical distance between the point and the line. A total sum-of-squares also is shown. By adjusting the slope and y-intercept, the user can try to find the optimum line by minimizing the total sum-of-squares. By moving data points, users also can explore the effect of outliers. The site does not provide an explanation of the mathematical details of a least-squares analysis, nor does it explain the significance of the sum-of-squares. Nevertheless, instructors will find that this is a useful tool for illustrating a least-squares analysis. Currently 4.50/5 1 2 3 4 5 Rating: 4.5/5 (2 votes cast) Simplex Optimization Methods   by Grabitech Details This site, from the developers of the software program Multisimplex, provides a basic introduction to simplex optimization. Topics include the basic simplex method, the modified simplex method and evolutionary optimization. Although the mathematical details are not included, the site provides flow charts showing the logic behind the optimization. The site assumes that the user understands the need for optimization and, therefore, is less suitable for beginners. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) NIST Engineering Statistics Handbook   by NIST Details This site provides a comprehensive electronic handbook on statistics for scientists and engineers. Topics include graphical approaches for exploratory data analysis, the characterization of measurement processes, the construction of statistical models for predicting and/or optimizing process, experimental design, process control monitoring, significance testing and the evaluation of product reliability. Although the site may be too detailed and complex for an undergraduate student to navigate without significant guidance, it is a useful resource for graduate students and practicing analytical chemists. Individual chapters can be downloaded as pdf files. The handbook provides numerous case studies and examples. Currently 4.00/5 1 2 3 4 5 Rating: 4.0/5 (1 vote cast) EqWorld: The World of Mathematical Equations   by Andrei D. Polyanin Details This site contains methods and exact solutions for a multitude of mathematical equations, including algebraic, differential, partial differential, integral, and functional equations. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Rice virtual lab in statistics   by David Lane Details This site is devoted to statistical tests and demonstrations of their use and was created with the support of the National Science Foundation. One section is a complete reference guide - the online statistics textbook, with detailed descriptions of all things statistical. The second, and most fun section, is simulations/demonstrations section where nearly twenty statistical tests are demonstrated with interactive Applets. Each Applet has clear instructions for use with details on the test demonstrated. A third section gives case studies where statistics have played a role, illustrating theory with specific analyses from court cases to who is buying iMacs. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Introduction to Factor Analysis   by Lochmuller, Charles H. Details This site introduces the application of factor analysis to chemical data. The tutorial, which uses data from a UV absorbance experiment, is designed for undergraduate chemistry students. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Reliable Measurements: A Guidebook for Trace Analysts   by Dr. Paul Gaines Details Provides a comprehensive resource on sample preparation and analysis for those interested in elemental determinations by atomic spectrometry, especially ICP-OES and ICP-MS. Issue such as sources of contamination, detection limits, sample preparation, standard stability, and method validation are well covered. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Applets for Chromatography, Signal Processing and General Analytical Chemistry   by Prof. C. E. Efstathiou Details This site offers Java-based applets as organized in 4 categories: analytical and general chemistry, instrumental chemical analysis, instrumentation/signal processing, data analysis/chemometrics. Each applet includes a short introduction followed by a user controlled input of experimental conditions, such as seen for diffusion in electrochemistry. Currently 5.00/5 1 2 3 4 5 Rating: 5.0/5 (1 vote cast) Statistics for Chemists   by R. Wehrens Details Excellent comprehensive resource on statistics, including information on descriptive statistics, confidence intervals, hypothesis testing, regression, ANOVA, experimental design, and multivariate statistics. Web-based exercises are interspersed throughout the text, allowing students to practice what they are learning and to obtain immediate feedback. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Statistics for Analytical Chemistry   by Scott van Bramer Details This site provides a brief reference on statistics that both analytical faculty and students will find useful. The site includes a series of problem sets and supporting MathCAD spreadsheets. Materials available on the website can be downloaded as a pdf file. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Principal Components Analysis Tutorial   by Lindsay I. Smith, Dept CS, U of Otago Details This site provides a clear introduction to the principle component analysis (PCA) without overwhelming the student. The tutorial includes a brief introduction and an explanation of the mathematics of PCA. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Prediction of Chemical and Biological Properties of Organic Compounds from Molecular Structure   by Jurs, Peter C. Details This website is a PDF file of 32 slides and accompanying notes that describe the process of determining quantitative structure activity relationships. The slides focus on the ADAPT software, but are generally useful to anyone interested in QSAR, and discuss the details of Structure Entry and Molecular Modeling, Descriptor Generation, Feature Selection, Model construction, and Model Validation. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Uncertainty Calculator   by Gary Bertrand Details This site contains a JavaScript "Uncertainty calculator," which determines the uncertainty of a calculated result given the uncertainties for the measurements. The website includes background material on calculating uncertainties and instructions for using the calculator. The software also is available as a free download. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Quality in Environmental Analysis   by Arizona State University Details This site contains a PowerPoint presentation that describes the terms and principles of quality assurance (QA) and quality control (QC) for environmental analysis. The presentation is easy to understand and QA explanations are concise. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Applications of Chemometrics   by Infometrix Inc. Details Examples of the use of chemometrics in clinical, petrochemical, and industrial analysis, from chromatographic and mass spectrometric data (PDF). Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) RPKP Experiments: Probability and Statistics   by Walker, John Details This site provides a basic introduction to probability and statistics. There is a detailed explanation of the normal distribution, with associated mathematics, as well as a treatment of the standard deviation, and the Chi Square test. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Statistics for Chemists: Exercises   by Wehrens, Ron Details This website contains a group of exercises that allow students to practice basic statistical calculations for descriptive statistics, confidence intervals, hypothesis tests, regression and experimental design. The exercises are interactive and provide feedback for students who submit wrong answers. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) The Probability Pipe Organ   by Walker, John Details This site provides a Java-based simulation that uses a random number generator to demonstrate the principles of probability. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) DynaFit - (Bio)Chemical Kinetics and Equilibria   by Kuzmic, Petr Details The freely available software package uses a nonlinear least-squares regression analysis to fit chemical kinetic, enzyme kinetic, or ligand-receptor binding data to a user-defined molecular mechanism represented symbolically by a set of chemical equations. Dynafit is available for Microsoft Windows XP or 2000. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) The Electronic Statistics Textbook   by StatSoft Details This electronic textbook on statistics provides both extensive and in depth coverage of statistics. Although an excellent reference for analytical chemistry students and faculty, the lack of chemistry-related practice problems or exercises may not make it an appropriate substitute for a traditional text. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Chemometrics   by Hardy, James K. Details An overview of techniques used in data analysis. Basic statistics, analysis of variance, principal component analysis, neural networks, and multivariate calibration are addressed. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast)   * editor's choice  Analytical Chemistry 2.0   by David Harvey Details A complete textbook for Quantitative Analysis is freely downloadable. Teach yourself Analytical Chemistry, or be part of a class on the subject. Currently 5.00/5 1 2 3 4 5 Rating: 5.0/5 (2 votes cast) All about Electrochemistry   by Stephen Lower Details Site contains introductory material in basic electrochemistry. Topics include galvanic cells, electrodes, cell potentials and thermodynamics, Nernst, batteries and fuel cells. Currently 1.00/5 1 2 3 4 5 Rating: 1.0/5 (2 votes cast) Analytical Electrochemistry: Basic concepts   by Richard S. Kelly Details This module focuses on the basic concepts involved in dynamic electrochemistry when the net current is not zero - the combination of mass transfer and electrochemical reactions at the interface between solids and fluids. It is at an introductory level appropriate for undergraduates in their sophomore or junior years. Currently 3.25/5 1 2 3 4 5 Rating: 3.3/5 (4 votes cast) Experiments in Electroanalytical Chemistry   by E. Kirowa-Eisner, D. Tzur, M. Brand and Ch. Yarnit Details This website offers educators a set of eight classical electroanalytical experiments suitable for use in a quantitative analysis, instrumental analysis, or electrochemistry course. The materials should be useful for advanced undergraduates and beginning graduate students. Experiments include coulometric, conductometric, and potentiometric titrations, stripping analysis, flow injection analysis, and polarography. It is important to note that several of the experiments use mercury or mercury coated electrodes which present safety concerns. Currently 5.00/5 1 2 3 4 5 Rating: 5.0/5 (1 vote cast) Analytical Electrochemistry: Potentiometry   by Erin Gross Details This courseware module is structured for either a lecture presentation or self-study tutorial on analytical potentiometry. The level of presentation spans upper high school to college students. Topics include historical background, theory/principles, instrumentation, pH electrodes, experimental examples, and troubleshooting tips. Currently 4.00/5 1 2 3 4 5 Rating: 4.0/5 (1 vote cast) Electrochemical Detection of Phenol Utilizing a Synthesized Sonogel-carbon Zirconium Oxide   by Suzanne Lunsford Details This experiment is designed for senior undergraduate students in an inorganic chemistry course. Students are asked to synthesize a sonogel-carbon electrode that is modified with a ZrO2 sol-gel and to compare the results to those of an unmodified electrode for the detection of phenol. Currently 5.00/5 1 2 3 4 5 Rating: 5.0/5 (1 vote cast) Analytical Electrochemistry: A Laboratory Manual   by Theodore Kuwana Details This labware module contains directions for seven experiments in analytical electrochemistry. The experiments are designed to illustrate fundamentals of electrode reactions as applied to readily accessible redox reactants. They provide insight to dynamic electrochemistry for scientists at all levels of training. Activation procedures to prepare glassy carbon electrodes are provided in a TechNote. Currently 5.00/5 1 2 3 4 5 Rating: 5.0/5 (1 vote cast) Anodic Stripping Voltammetry   by Michigan State University Details Site provides basics with illustrations of what happens during deposition and stripping of metals for analysis by anodic stripping voltammetry (ASV). The PDF presentation is easy to navigate and understand. It can be used as a supplement to a lecture or lab. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Linear and Cyclic Voltammetry   by Bioanalytical Systems Details This website provides an introduction to linear sweep and cyclic voltammetry. The shape of the current-voltage curve for these techniques is explained with illustrations of the concentration profiles from the electrode surface into the solution at different stages of an electrochemical reduction. Currently 5.00/5 1 2 3 4 5 Rating: 5.0/5 (1 vote cast) Electrochemistry Listings   by Science and Research Details Listing contains titles and links to over 40 sites, like journal articles, course and tutorial material, simulations, batteries, corrosion and other resources. Currently 3.00/5 1 2 3 4 5 Rating: 3.0/5 (1 vote cast) Study of Electrode Mechanism by Cyclic Voltammetry   by Fairbrother, D. Howard Details This lab experiment uses cyclic voltammetry to determine the concentration of acetaminophen (active ingredient of Tylenol) in a children's pain relief elixir and to study the pH dependent mechanism of its oxidation. The experiment includes theory, pre-lab, write-up instructions and reference article. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Synthesis of a Sonogel-Carbon Modified Sensor Electrode with Titanium Oxide (TiO2) to Detect Catechol   by Suzanne Lunsford Details This experiment demonstrates cyclic voltammetry, surface modification, selectivity, and bioanalysis in assaying catechols in the presence of ascorbic acid. Pre- or post-lab questions are included, along with sample student data and instructor's notes. Currently 1.00/5 1 2 3 4 5 Rating: 1.0/5 (1 vote cast) Cyclic Voltammetry Simulator   by Vining, William Details This simulator allows the modeling of responses from experiments in cyclic voltammetry, and is applicable to a wide variety of parameters. Excellent instructional aids in text form include description of electrochemical reversibility, diffusion, instrumentation and interpretation of cyclic voltammograms, with real-time demonstration of parameter changes. Currently 4.50/5 1 2 3 4 5 Rating: 4.5/5 (2 votes cast) Electrochemical Encyclopedia   by Zoltan Nagy, Editor Details This site contains a compendium of 44 links to articles in electrochemistry, many of which are outstanding in quality. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Electrochemistry and Detection of Organic and Biological Molecules such as Catechols   by Suzanne Lunsford Details This ASDL online article describes a lab experiment whereby students learn how to prepare a conducting thin-film polymer electrode for the analysis of catechol and the effect of ascorbic acid on the cyclic voltammetric results. Currently 4.00/5 1 2 3 4 5 Rating: 4.0/5 (1 vote cast) Educator's Reference Guide for Electrochemistry   by Pine Instrument Co. Details This is a 70 page primer on analytical electrochemistry of interest to faculty, students and practitioners wanting to learn about basic concepts and applications. Currently 4.00/5 1 2 3 4 5 Rating: 4.0/5 (2 votes cast) Famous Scientists - Electrochemists   by Eugenii Katz Details This webpage provides biographical sketches of an exhaustive array of scientists from the mid-1500\\\'s through today whose work has significantly impacted the field of electrochemistry. Index pages with portraits and summaries of the scientists are available in groupings by era. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Experimenting in Picoliter Microvials   by Andrew Ewing Details This is a 1998 ACS article that provides detailed instruction on handling small volumes with micro- to pico-liter vials. This is Instructional for students working in domain of ultra-small samples. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Electrochemical Education   by Marty St. Clair, Coe College, Cedar Rapids, IA Details The purpose of this site is to collect in one location resources useful to educators attempting to incorporate modern electrochemical techniques into the undergraduate chemistry curriculum. Contains links to material on experiments, equipment, proposal writing, etc. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Potentiostats   by Bank Electronik Details This PDF document (52 pages) provides a comprehensive discussion of background history, theoretical considerations, electronic circuitry and design of potentiostats. Subject is treated in depth not found in textbooks, although computerized formats are not included. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Detecting subsecond dopamine release with fast-scan cyclic voltammetry in vivo   by R. Mark Wightman and students Details This article from Clinical Chemistry describes the technique of fast-scan cyclic voltammetry (FSCV, > 100 V/s) as applied in vivo for the detection of dopamine release and uptake. It is a good follow-up to an earlier paper by Stamford and Justice that is also in asdlib. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Cyclic Voltammetry   by Kennesaw State University Details This site provides an excellent experiment involving cyclic voltammetry at a gold electrode. The experiment includes a detailed introduction to the topics of electrode capacitance, electrode reactions, and flux of the electroactive species to electrode surface. Lab report guidelines and post-lab questions are included. Currently 3.00/5 1 2 3 4 5 Rating: 3.0/5 (1 vote cast) Experiments in Electrochemistry   by Giorgio Cargoni Details Experiments with batteries, made from readily available materials, are designed for upper elementary and high school students to learn about the rudimentary principals of electrochemistry. Currently 4.00/5 1 2 3 4 5 Rating: 4.0/5 (1 vote cast) The Fluoride Ion Selective Electrode Experiment   by David L. Zellmer Details This is an experiment for the determination of fluoride ion with an ion selective electrode (ISE). While some experimental guidelines are given, students are left to choose appropriate standard concentrations and sample type, and to develop their own experimental procedure. Currently 1.00/5 1 2 3 4 5 Rating: 1.0/5 (1 vote cast) Fast Scan Voltammetry   by Richard C. Compton Details A short presentation of theory and practice of electrochemistry focused on use of microelectrodes and micro-bands in flow cells. Problems encountered are addressed and response characteristics discussed. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Electrochemistry Resources   by Research Solutions and Resources Details This is a general interest website in electrochemistry, offering answers to many common questions. Sections include impedance spectroscopy, quartz crystal microbalance, reference electrodes, simulation voltammetry, potentiostats and handling of mercury. A list of web and book references is available, as is a \\\"contact us\\\" tab for questions to the author. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Potentiometry   by Garrett, Simon J. Details This link contains a set of lecture notes with illustrations from the potentiometry section of CEM 333, Instrumental Analysis at Michigan State University. Topics include potentiometric electrodes and their underlying theory, along with useful hints in their application. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) A Beginners Guide to Ion-Selective Electrode Measurements   by Rundle, Chris C. Details A relatively comprehensive presentation of the theory, types, practices, and errors associated with ion selective electrodes. Information is listed in a hyperlinked table of contents. The last section of the site includes a thorough glossary of terms. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Determination of DNA Bases Chemistry: A Discovery-Based Experiment   by Richter, Mark M. Details The paper contains details of an electrochemistry lab where students are given the time to explore and design an experiment to identify the different DNA bases. The paper has a very useful compendium of literature relating to electrochemical techniques. Currently 1.00/5 1 2 3 4 5 Rating: 1.0/5 (1 vote cast) Redox Potentiometry   by Crofts, Antony Details This site contains materials from a lecture course in Biophysics, covering activity, free energy, equilibrium constants, and effect of pH on redox potentials, potentiometry, and reaction rates. The redox-specific content is based on interesting biological reactions not often found in chemistry texts. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Cyclic Voltammetry   by Severin, Kathryn G. Details This site provides an excellent experiment involving cyclic voltammetry at a gold electrode. The experiment includes a detailed introduction to the topics of electrode capacitance, electrode reactions, and flux of the electroactive species to electrode surface. Lab report guidelines and post-lab questions are included. Currently 1.00/5 1 2 3 4 5 Rating: 1.0/5 (1 vote cast) Analytical Chemistry   by Hardy, James K. Details Lecture notes for 1st semester are on titrations, gravimetry, kinetics and electrochemistry (redox). Potentiometry, coulometry, voltammetry, spectroscopic and separation methods are presented during 2nd semester, illustrated with QuickTime animations. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast)   * editor's choice  Analytical Chemistry 2.0   by David Harvey Details A complete textbook for Quantitative Analysis is freely downloadable. Teach yourself Analytical Chemistry, or be part of a class on the subject. Currently 5.00/5 1 2 3 4 5 Rating: 5.0/5 (2 votes cast) Introduction to Lasers   by Carol Korzeniewski Details Lasers are preferred light sources for high resolution or time-resolved optical spectroscopy. This module introduces the workings of lasers and gives examples of common designs. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Electronics - Tutorial   by Wayne Storr Details An encyclopedic collection of descriptions of electronics circuitry and principles to introduce or reacquaint readers with a wide variety of concepts. The site is very well organized to access the information needed. In addition to passive and active components, electricity and magnetism are also described. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Light sources - Technical Information   by Newport Details This is a commercial site with some detailed information included with product announcements. The discussion of light collection is an exceptional introduction to matching optical elements with maximum throughput. There are also illustrative spectra of typical sources and descriptions of laws of radiation and radiation units. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Electro-Optics Handbook   by Burle Details The Electro-Optics handbook is a 14 chapter reference text which addresses sources of radiation, including lasers, detection and detectors, photometric quantities, and geometric optics. Specific details can be found with the extensive appendix. The text is technical and lists equations without derivations. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Photodetectors and Fiber Optics   by Ken Crozier Details Power point slides to support a lecture on the principles and usage of photodiodes and optical fibers for sensors and instrumentation. There is no supporting text for the slides. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Photodiode Technical Guide   by Hamamatzu Details This website by Hamamatsu provides a fairly extensive presentation on the fundamentals and operational characteristics of a photodiode. One can learn about what governs the spectral response region, the gain characteristics and how to couple to an amplifier for the final output stage. It is an excellent primer for anyone wishes to learn about photodiodes. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Introduction to Dynodes   by Tom Jordan Details This site is presented as a guided exploration into the operation of a photomultiplier from the first light incidence to the output signal. Questions guide the exploration and allow (sometimes require)the student to speculate on the result before going forward. A careful, patient student will get a thorough introduction to the operation of a dynode and how to bias it. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) PMT HandBook   by Hamamatzu Details This commercial site is an extensive description of the fundamentals and applications of photomultipliers including their characteristics, structures, operating parameters, and applications areas. The contents are provided in 14 chapters covering 323 pages that include nearly everything that you ever wanted to know about photomultiplier tubes. Reading the text and accompanying illustrations with patience and care, you can become an expert on the subject. It will allow the practitioner to use this as a guide in not only understanding how a PMT works but moreover, have sufficient knowledge to built an instrument with the right selection of a specific PMT. Chapter 14 provides a wide range of illustrative applications, from a simple spectrophotometer to confocal microscopes to scanning electron microscopes to positron imagers. This is an excellent source of information for those interested in learning fundamentals and applications of instruments based on monitoring light or particles. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) An Inexpensive Field-Programmable Potentiostat   by Dale Russel Details This website describes the practical design and construction of a small, inexpensive programmable potentiostat including a list of the components and circuitry for building a complete self-contained potentiostat - all for approximately $50 in component cost. Explanation is given about the basics and the operational characteristics of this potentiostat, illustrated by running cyclic voltammetric scans of potassium ferricyanide in a 3-electrode cell. The noise, as seen by the small oscillations on the voltammograms, may be lessened by the use of a shielded/grounded case with use of BNC connectors for attaching the electrodes to the potentiostat. Some of the components may no longer be manufactured and may have to substituted with equivalent available parts. Students interested in analytical instrumentation or electrochemistry, including projects involving field-portable electrochemical instrumentation, might also find this potentiostat useful. This is a good example of a practical instrument/ circuit design. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Quantitative Spectroscopic Calibration   by Howard Mark Details Spectroscopic calibration is the process of using mathematical calculations to relate spectroscopic measurements to chemical composition. Several algorithms can be used to perform these calculations. Success depends on selecting a suitable set of calibration samples to “train” the system, using the correct algorithm to match the characteristics of the measured data, and properly evaluating and validating the calibration model developed. Various aspects of calibrating spectroscopic instruments to perform quantitative analysis are discussed. The article ends with an overview of the various algorithms that are available to perform the calibration process. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Handbook of Operational Amplifier Applications   by Texas Instrument Details The Handbook of Operational Amplifier Application is a complete and exhaustive compendium of Op Amp information. Chapters start with the basic electronics of the internal circuitry of op amps, feedback and analysis of operation followed by ideal and practical op amps. The remaining chapters provide numerous application circuits. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Tunable Monochromator Movie   by Thomas G. ChasteenChasteen Details This Quick Time movie illustrates and describes to operation of a Czerny-Turner monochromator. The slits, mirrors, grating and grating scan are described in the production of a specific wavelength at the outlet slit. The movie is a companion to the double beam spectrometer animation. Currently 1.67/5 1 2 3 4 5 Rating: 1.7/5 (3 votes cast) Optical Tweezers: Measuring Piconewton Forces   by Mark Williams Details This is a comprehensive reference article for optical tweezers technology. It outlines application of this technique in the piconewton force measurement for biological samples. The article includes principle of the technique, calibration, and examples of the use of this technique in one single article. The paper is easy to read, self-contained, and complete. It supplies a good mix of theory and application, with interesting descriptions involving measurements with RNA and DNA. One needs to have a basic background in physics and biology to understand the theory and applications. The article is written at the senior level for undergraduates as well as graduate students. The content is acceptable for ASDL. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Concepts, Instrumentation and Techniques in Atomic Absorption Spectrophotometry   by Richard D. Beaty and Jack D. Kerber Details This pdf file contains a well written and thorough introduction to atomic absorption suitable for use by undergraduates and faculty teaching instrumental analysis courses. Topics covered in the document include theoretical concepts and definitions, flame atomic absorption, instrumentation, analytical interferences, sampling techniques, graphite furnace atomic absorption, and plasma techniques. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Introduction to Signals and Noise: eLearning Module   by Steve Petrovic Details Basic concepts of signals, noise, and extraction of data from noisy signals are presented as an e-learning module. Excel spreadsheets allow students to vary noise parameters. Basic electronics ideas relating to RC circuits support introductory information on filters Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) LabVIEW for Instrumental Analysis   by Mark Jensen Details This site provides two useful resources for instructors and students of analytical chemistry. The first is a collection of LabVIEW virtual instruments (VIs) for demonstrating topics such as signal-to-noise ratios, boxcar and ensemble averaging, power spectra, digital filtering, analog-to-digital conversions, and the Nyquest frequency. For users that do not have a working copy of LabVIEW, executable versions are included that use LabVIEW's free run-time engine (Windows only). The second set of resources is a series of tutorials for teaching students how to write their own VIs. The tutorials are well thought out and nicely build on each other. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Encyclopedia of Analytical Instrumentation   by Brian M. Tissue Details Site contains a comprehensive introduction to a large number of analytical instruments, their components and techniques. Example topics: basic concepts/methods, data acquisition and electronics, data handling, electrochemistry, imaging, material and surface analysis, sensors, spectroscopy, etc. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Introduction to X-ray Diffraction (XRD)   by Heather Bullen Details This learning module presents the fundamentals of X-ray Diffraction for characterizing molecular structure in a form useful both as lecture notes and for self-study. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Optics Tutorial   by Jeremy Learner and A. Thevenon Details This site provides a tutorial on electromagnetic waves using animated graphics. The tutorial gives the student the ability to visualize circularly polarized waves, the superposition of various types of polarized waves, and the change that results when the EM waves interact with matter. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) X-ray Diffraction   by Peter Goodhew Details This site is a good freshman or sophomore level introduction to diffraction and its application to studying crystal structure. Because it's very visual and interactive, it engages the student. It's not mathematical enough for an upper level course. The basics of diffraction are covered with excellent interactive demos. Demos are great as a supplement but not as a stand alone module on diffraction. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Fourier Transform   by Brian M. Tissue Details An overview of the Fourier theorem as applied to analytical measurements is given. The Discrete Fourier Transform and the Fast Fourier Transform algorithms are mentioned, and sampling requirements are discussed. Links are provided to descriptions of Fourier transform based mass spectrometry, infrared spectroscopy and NMR techniques. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Bragg's Law and Diffraction   by Konstantin Lukin Details This site presents an introduction to Bragg's Law of Diffraction, along with how diffraction of x-rays provides information on atoms in crystalline material. An Applet allows the user to vary the wavelength and angle of incidence of radiation to a surface, along with the distance between layers of the material to demonstrate the conditions necessary for constructive interference, or a Bragg's condition. The derivation of Bragg’s law is also explained. Currently 3.00/5 1 2 3 4 5 Rating: 3.0/5 (1 vote cast) ICP-MS   by Jenna Worley and Steve Kvech Details This site provides the principles of ICP-MS from sample introduction, ionization to MS quadrapole analysis. Excellent illustrative schematics of the main process in ICP-MS and pictorials of component parts. This has photos of the detector horn; photos of the actual quadrapoles; and of the plasma which are nice. The site has animations showing the nebulization (although not really related to any physical operation) and to the quadrapole. This material would serve as an excellent reference resource by students at the upper undergraduate and beginning graduate level. The detection levels for 27 elements are listed in a table. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) UV-visible spectroscopy   by Jim Clark Details This webpage, part of a larger project "Understanding Chemistry", provides a solid introduction to UV-vis spectroscopy suitable for use in introductory chemistry and introductory analytical chemistry courses. The UV-vis pages discuss UV-vis light, absorption, Beer's law, the double-beam spectrometer, and introduce some standard applications of UV-vis spectroscopy. Explication is clear and thoughtful. Judicious and effective use of graphics. Site is easy to navigate, and the links work. Some typos. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Applets for Chromatography, Signal Processing and General Analytical Chemistry   by Prof. C. E. Efstathiou Details This site offers Java-based applets as organized in 4 categories: analytical and general chemistry, instrumental chemical analysis, instrumentation/signal processing, data analysis/chemometrics. Each applet includes a short introduction followed by a user controlled input of experimental conditions, such as seen for diffusion in electrochemistry. Currently 5.00/5 1 2 3 4 5 Rating: 5.0/5 (1 vote cast) Landmark Instruments of Chemistry   by Richard H. Bromund Details This website effectively uses animated movies combined with text explanations to describe the processes in FT-IR interferometry, TLC, GC and magnetic sector mass spec. It is effective in illustrating processes that are otherwise difficult to visualize. These materials are excellent visualization tools that can be incorporated into lectures readily. Currently 4.00/5 1 2 3 4 5 Rating: 4.0/5 (1 vote cast) Basic Microscopy Concepts   by Nikon Details The site provides introductory information related to optical microscopy. Among the topics addressed are resolution, numerical aperture, depth of field, field of view, illumination and the useful magnification range. A section on fluorescence microscopy is also included. Interactive video is used to demonstrate concepts in some cases. Researchers and educators interested in a brief overview of optical microscope principles may find the site useful. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) FTIR Spectrometry   by Paul L. Edmiston Details The site demonstrates principles behind the operation of the interferometer in an FTIR spectrometer. Graphics and interactive movies are used. Examples start from a single wavelength and build to the superposition of multiple wavelengths. The connection between an interferogram and a frequency domain spectrum is discussed. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Electrochemical Encyclopedia   by Zoltan Nagy, Editor Details This site contains a compendium of 44 links to articles in electrochemistry, many of which are outstanding in quality. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Experimenting in Picoliter Microvials   by Andrew Ewing Details This is a 1998 ACS article that provides detailed instruction on handling small volumes with micro- to pico-liter vials. This is Instructional for students working in domain of ultra-small samples. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Flow Injection Analysis   by Monash University Details This website by Monash University provides a primer for those who are beginners as well as those who wish to have a refresher on the principles and illustrative applications of flow injection analysis (FIA). The left hand menu allows selection of topics: FIA, Princples, Dispersion Process, Modes of Applications, Recent Developments, Bibliography and People in FIA. Schematics and illustrative signal outputs are provided for each FIa method. The site is easy to browse with links to subtopics. The site is unique in terms of bringing together in one place the basics of FIA with illustrations. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) GlobalFIA   by GlobalFIA Details This site by GlobalFia provides a tutorial on the general aspects of flow injection analysis (FIA), sequential injection analysis (SIA) and the newly coined zone fluidics. Thus, it serves as an excellent resource for teaching flow methods to both undergraduates and graduate students, and as a refresher to practitioners. The tutorials are divided into 9 sections: introduction, fundamentals, dispersion, enrichment, chemistry, SIA, zone fluidics and bibliography. This modular approach makes information on concepts easy to digest and builds sequentially on each previous module with accompanying illustrative graphics. The bibliography provides references to hardcopy primary sources and a link to the FIA database at U. North Florida. The step-by-step instruction for the development of a new SIA method could be very helpful to someone who may be starting a new system or wishing to develop and new experiment. The site is easy to browse. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Potentiostats   by Bank Electronik Details This PDF document (52 pages) provides a comprehensive discussion of background history, theoretical considerations, electronic circuitry and design of potentiostats. Subject is treated in depth not found in textbooks, although computerized formats are not included. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Organic Chemistry On Line   by William Reusch Details This site covers introductory material related to the analysis of small organic molecules by mass spectrometry, UV-visible, IR, and NMR spectroscopy. A concise explanation of each approach is presented with illustrations. This would be useful for those teaching organic chemistry and for others who need a review of the topic. The section on Spectroscopy Resources at the end of the site contains a list of links to additional information plus a several links to compilations of problems (and their solutions) that challenge the student to interpret NMR or IR spectra. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Basic Concepts of Optical Microscopy   by M.W. Davidson and M. Abramowitz Details A comprehensive primer focused on the basic optical microscope, as well as the electron, confocal, polarizing, and stereoscopic microscopes. Virtual microscopes allow the user to simulate the use of a variety of real-life microscopes. There are galleries of photomicrographs illustrating a variety of specimens. This website provides complete instructional materials on the theory of light and the applications of microscopy to a variety of analytical problems. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) The Practical Application of Light   by Melles Griot Corp. Details This commercial website is a good tutorial on optical design. While users should know a few freshman physics ideas about the nature of light and imaging, the novice optical designer can start from scratch using the material provided by Melles Griot. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) RSC.org: Mass Spectrometry   by Royal Society of Chemistry- Univ. Warwick Details This video, distributed on YouTube by the Royal Society of Chemistry is on the basic principles of mass spectrometry, using a magnetic sector instrument to demonstrate how specific m/z ratios can be selected. The theory and operation of MS, including the chemistry of ionization and fragmentation is described at an introductory level. There's also an excellent example of the use of high resolution MS to differentiate between nominal mass and actual mass. The video does a very good job of explaining the concept such that only a little background knowledge is required. The video is short enough (6 mins), that it would be very useful in a class setting or for students outside of class. The ultimate strength of this video is the general nature of the content that makes it appealing to a wide audience. The video may be most appropriate in a lower-level general education science course (i.e forensic science) or as a quick orientation video for instrumental analysis students prior to introducing mathematical or operational concepts. This video would also be helpful for a lay science person who wishes to learn more about mass spectrometry from a general interest perspective. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Accelerator Mass Spectrometry in Biology and Health Care   by Lawrence Livermore Lab Details This video, developed at Lawrence Livermore National Laboratory, describes the instrumentation for accelerator mass spectrometry and its applications. The video describes the instrumentation and its application for carbon dating and measurements of drug distribution. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Fundamentals of GC/MS   by Shimadzu Europa GmbH Details This tutorial provides an excellent introduction into the fundamentals of GC/MS. The tutorial consists of five sections: An introduction of mass and types of ions, ionization modes, hardware, figures of merit describing mass analyzer performance, and qualitative methods of GC/MS analysis - including library searches. Each section contains animations or simulations of chemical and physical interactions that pertain to mass spectrometry such as gas-phase ionization processes, fragmentation, mass analyzers, the importance of a vacuum, and detectors. A basic introduction to gas-liquid chromatography is also provided. The tutorial is intended to describe GC/MS at an introductory level, but does include theory at an intermediate level, which may be included or not depending on the intended audience. Information is presented in a Powerpoint style, and each figure has a Details tab which provides additional information on the subject. This website has excellent pedagogical value for students and new practitioners. Currently 3.00/5 1 2 3 4 5 Rating: 3.0/5 (1 vote cast) Fourier Transform   by Brian M. Tissue Details An overview of the Fourier theorem as applied to analytical measurements is given. The Discrete Fourier Transform and the Fast Fourier Transform algorithms are mentioned, and sampling requirements are discussed. Links are provided to descriptions of Fourier transform based mass spectrometry, infrared spectroscopy and NMR techniques. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) ICP-MS   by Jenna Worley and Steve Kvech Details This site provides the principles of ICP-MS from sample introduction, ionization to MS quadrapole analysis. Excellent illustrative schematics of the main process in ICP-MS and pictorials of component parts. This has photos of the detector horn; photos of the actual quadrapoles; and of the plasma which are nice. The site has animations showing the nebulization (although not really related to any physical operation) and to the quadrapole. This material would serve as an excellent reference resource by students at the upper undergraduate and beginning graduate level. The detection levels for 27 elements are listed in a table. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Understanding Chemistry   by Jim Clark Details This website part of a larger project "ChemGuide" provides a nice introduction to mass spectrometry that is suitable for use by introductory analytical chemistry students. Content includes an introduction to the instrumentation, explanation of fragmentation and how it can be used to identify compound structure, the origin of the M+ and (M+1)+ peaks. Each section is succinct, well written and provides a simple example. As such the site should be useful to faculty introducing mass spectrometry in the analytical classroom and to chemistry students. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Mass Spec Primer   by Waters Corporation Details This website developed by Waters Corporation provides a brief primer on mass spectrometry which includes information on instrumentation, a discussion of mass accuracy, resolution, and LC-MS. As such the site should be a valuable resource for both students and faculty. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) HPLC, LC-MS, and FTIR sites   by Shula Levin Details This site contains a considerable amount of information on HPLC, LC-MS, and FTIR via linked sites by the same author and some vendor sites. It may require considerbale time to follow the links to find specific information, but as a collection of sites related to HPLC and FTIR it is quite useful as a teaching resource. There are some interesting animations that might be helpful for students to understand how these instruments work. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) GC/MS with animations   by Dr. Thomas G. Chasteen Details This site contains a good review of GC detectors that is linked to animated files describing the hardware and principles of operation for GC/MS. From this site, one can also get to multiple other animations about a variety of analytical topics. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) The Macrogalleria -- A Cyber Wonderland of Polymer Fun   by Dept. of polymer science, U. of Miss. Details This site is devoted to analysis of polymers and focuses on SEC, although links to other techniques are provided. It does not go into great detail, but provides a nice overview of critical ideas behind SEC. The link to molecular weight distributions may alos help some students with the concepts behind polymers and polymer analysis. It is written simplistically and in an informal manner, which may put some people off, but others might enjoy it for this reason. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Chromatography and Mass Spec Lectures   by Prof. Jose-Luis Jimenez , U. Colorado Details This site contains mass spectrometry and chromatography lecture notes for a graduate course. They are subdivided by topic (history, theory, etc.) and are easy to browse. They may be helpful to someone constructing their own course in chromatography and/or mass spectrometry. The notes are fairly complete. The historical sections may particularly save time in preparing courses. The notes also provide good information and a helpful outline to follow. The site also has some nice mass spectrometry animations from Thermo. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Landmark Instruments of Chemistry   by Richard H. Bromund Details This website effectively uses animated movies combined with text explanations to describe the processes in FT-IR interferometry, TLC, GC and magnetic sector mass spec. It is effective in illustrating processes that are otherwise difficult to visualize. These materials are excellent visualization tools that can be incorporated into lectures readily. Currently 4.00/5 1 2 3 4 5 Rating: 4.0/5 (1 vote cast) CASE TEACHING NOTES for Filthy Lucre   by Ed Acheson Details The website presents a case study involving the detection of cocaine on dollar bills. The case study uses GC-MS, but has an introduction appropriate for beginning chemistry students. Currently 2.00/5 1 2 3 4 5 Rating: 2.0/5 (1 vote cast) Animation of Quadrupole GC-MS detection   by TRSL Details An animation site which deals specifically with quadrupole mass spectrometry detection for chromatography. The animations are short (one to two minutes) and can easily be shown in class as part of a lecture. They are extremely helpful in illustrating key components and concepts of chromatographic systems. Users are encouraged to explore the site and the other brief animations as well. Separate links to other simulations by the same company (TRSL) are also listed on ASDL. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Application Notes From LECO   by Halminem, Chris Details Application notes and experimental protocols for a variety of inorganic and organic analytes. Topics covered include analysis of food and beverage samples, natural products, pharmaceuticals, environmental contaminants and industrial applications. The main techniques described are near infrared spectroscopy, liquid and gas chromatography, time-of-flight mass spectrometry and glow discharge optical spectroscopy. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Introduction to Mass Spectrometry   by Siuzdak, Gary Details This site contains an on-line text on mass spectrometry at the intermediate level. The text gives good general coverage of mass spectrometry instrumentation and applications in very readable format. It contains nice diagrams that provide a visualization of the ionization and mass selection processes. It also contains an overview of applications of mass spectrometry near the end that is different than most sites related to MS. It is especially appropriate for intermediate students. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Mass Spectra of Fatty Acids   by W.W.Christie Details This website on lipid mass spectra presents a nice overview of the topic of mass spectrometric determination of fatty acids with gas chromatography-mass spectrometry and electron impact ionization sources (including derivatization). at a level that should be accessible to undergraduate analytical students. The site is easy to navigate. The material is well written and generously referenced. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) A Glossary for Mass Spectrometry   by Busch, Kenneth L. Wyvern Associates  Details A compilation of some of the more widely used terms that non-mass spectrometrists may encounter, and for which a simple definition would be helpful. (3.5 MB PDF file) Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) An Eye on Food   by Stephen K. Ritter Details This C and E News cover story from July 2005 introduces readers to the concept of quality control in food analysis for food safety with an emphasis on the application of near-infrared (NIR) and encoded photometric infrared (EP-IR) spectroscopy, Fourier transform ion cyclotron resonance mass spectrometry (FT ICR MS), and microchip analysis. This article would be of potential use to faculty teaching any of these topics in their classroom. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Organic Chemistry On Line   by William Reusch Details This site covers introductory material related to the analysis of small organic molecules by mass spectrometry, UV-visible, IR, and NMR spectroscopy. A concise explanation of each approach is presented with illustrations. This would be useful for those teaching organic chemistry and for others who need a review of the topic. The section on Spectroscopy Resources at the end of the site contains a list of links to additional information plus a several links to compilations of problems (and their solutions) that challenge the student to interpret NMR or IR spectra. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) VMSL: Virtual Mass Spectrometry Laboratory   by Joseph J. Grabowski Details This site presents a series of case studies that can be explored using modern mass spectrometry methods. The problem-solving nature of the site provides students a virtual laboratory experience that can supplement access to mass spectrometry instrumentation. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) What is Mass Spectrometry?   by Chiu, Chia M. Details This site is a very thorough page by page description about what mass spectometry is and how it is used. It has many useful figures and references to other materials. The site is well organized and easy to use. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) IonSource   by IonSource.com Details This website contains a wealth of information about mass spectrometry for bioanalysis and related subject material for biotechnology. There are four significant components: The Card Index, Featured IonSource Tutorials and Contributions, Resources, and Links. The contents will serve as a learning tool for students, faculty and practitioners alike. You can take what you want, depending on your level of expertise and interest. The Card Index contains information on things like peptide mass calculator, acetylation reaction, protein glycosylation, phosphorsylation and MS lab calculation, etc., will be useful. Learners will find the tutorials helpful to learn about Principles of MS quantitation, Isotopes, Reverse Phase HPLC Basics, etc - and if you look under shareware/freeware, several free softwares available on the Internet are listed. This site contains a compendium of material that is not available in textbooks. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Introductory Tutorial to Mass Spectrometry   by Breci, L. Details An introduction to GC-MS for beginning students in analytical or organic chemistry lab. The site includes discussion of quadrupole mass analyzers, ionization, detection, and interpretation of mass spectra. One of the best features of this site is a series of on-line quizzes on the interpretation of EI mass spectra that includes hints as well as explanations of why the answers are right or wrong. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Introduction to Mass Spectrometry   by Tissue, Brian M. Details An introduction to mass spectrometry, primarily an overview of ionization methods and mass analyzers with diagrams that provide visualizations of the topics discussed. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) The History of Mass Spectrometry   by imass.com Details This site provides a brief history of the development of mass spectrometry. The works of Thompson and Aston are presented along with a brief overview of the modern evolution of mass spectrometry. This site will be useful for beginning students interested in a historical overview of the field of mass spectrometry. This is an archived version of the site. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Interpreting Electrospray Mass Spectra   by Ion Source Details This site is a tutorial on interpretation of electrospray mass spectra of multiply charged molecules. It provides a simple explanation of the electrospray process and the potential for the creation of multiply charged species, especially when working with peptides. The mathematics of determining the charge state and molecular weight of the peptide is also explained. Although this site provides a good foundation on electrospray MS of peptides, students requiring an advanced understanding of MS fragmentation of proteins and peptides will have to go elsewhere. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Accuracy and Resolution   by Matrix Science Ltd Details This site focuses on mass accuracy and resolution. Examples are presented illustrating the difference between the average and monoisotopic masses. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Analytical Chemistry   by Hardy, James K. Details Lecture notes for 1st semester are on titrations, gravimetry, kinetics and electrochemistry (redox). Potentiometry, coulometry, voltammetry, spectroscopic and separation methods are presented during 2nd semester, illustrated with QuickTime animations. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Integrated Spectral Database System for Organic Compounds   by Kinugasa, S. Details Searchable database of infrared, NMR, and mass spectra of organic compounds. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Mass Spectrometry for Chromatographers   by Hardy, James K. Details This short course looks at mass spectrometers as detectors for gas chromatography. Includes instrumentation, spectral interpretation, data collection, worked problems, and a knowledge quiz. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Quantitative NMR   by Cynthia Larive Details A learning module focused on principles and practice of NMR for quantitative analysis, an application less commonly associated with the technique than is structure determination. Links to simulation packages are included. Currently 5.00/5 1 2 3 4 5 Rating: 5.0/5 (2 votes cast) Fluorine NMR   by J. T. Gerig Details This article describes the use of fluorine (19F) NMR for the analysis and structure determination of biomaterials. Using a traditional text-with-figures format, the article gives an overview of the synthesis of 19F spin-labeled materials and detailed descriptions of 19F chemical shifts and relaxation phenomena as applied to both primary and tertiary structure determinations of biochemical interest. Currently 2.00/5 1 2 3 4 5 Rating: 2.0/5 (1 vote cast) A Pictorial Representation of Product Operator Formalism: Non-Classical Vector Diagrams for Multidimensional NMR   by Biophysical Society; Donne and Gorenstein Details This site presents a pictorial description of the product operator formalism using a non-classical vector approach. This approach allows for the representation of any arbitrary multidimensional or heteronuclear NMR experiment. A description of a complete set of 16 vector representations for weakly-coupled two-spin (I=1/2) systems is given followed by an extension of this set to three-spin systems. Finally the concepts of coherence transfer, multiple quantum spectroscopy and phase cycling are illustrated using 2D COSY, 2D INADEQUATE, DEPT and sensitivity-enhanced HSQC as examples. The content is geared to those that have some background in NMR spectroscopy, and is probably most appropriate for a graduate course in NMR. This site can be used as a teaching tool as well as by practitioners who would like to easily deconstruct a pulse sequence for a better understanding of the “spin engineering” involved. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) NMR of Paramagnetic Proteins   by Biophysical Society; Bertini and Luchinat Details This site presents an overview of techniques used for structural elucidation of paramagnetic metalloproteins. The content is directed to the more advanced NMR user and would be suitable for an upper division or graduate level NMR class. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Fundamentals of NMR   by Biophysical Society, Thomas James Details This e-text presents an introduction to the fundamentals of NMR covering magnetic resonance, pulsed NMR, relaxation, chemical shift, spin-spin coupling, the nuclear Overhauser effect and chemical exchange. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) NMR tutorial   by Dekek Bogdal, Politechnika Krakowska Details The introduction to this site provides an entry-level introductions to NMR in a text + figures format. The site also contains two example structure elucidation problems using NMR. IR and MS data complete with hints and answers. Although the molecules are pretty simple, the examples do a good job of illustrating the structure elucidation process. The site also has data for 5 more complex structure determination problems. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Fourier Transform   by Brian M. Tissue Details An overview of the Fourier theorem as applied to analytical measurements is given. The Discrete Fourier Transform and the Fast Fourier Transform algorithms are mentioned, and sampling requirements are discussed. Links are provided to descriptions of Fourier transform based mass spectrometry, infrared spectroscopy and NMR techniques. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Solid State NMR   by Rob Shurko Details This website introduces both theoretical and experimental solid state NMR. The subject matter is covered thoroughly. The material is presented with numerous examples that are easy to follow, regardless of one's background. The subject matter is extremely well organized and a pleasure to read. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) NMR Spectroscopy: Lab 8   by Sergei N. Smirnov Details A complete NMR laboratory exercise from a set of fifteen (15) experiments in various topic areas developed for a physical chemistry laboratory at New Mexico State University. Excellent introductory material is provided, along with links to additional sources of information, including NMR tutorials. Pre-lab questions are presented along with detailed laboratory procedures. The two part experiment has students first measure proton spectra for a set of unknown substances and to match the spectra with the compound in a list provided, followed by a kinetics measurement. While the procedure is specific to Varian instruments, users should be able to easily modify the parameters to their own instrument. Site authorization is required to use some of the embedded links, but even without that access, this experiment should be of interest to instructors in both instrumental or physical chemistry. Currently 3.00/5 1 2 3 4 5 Rating: 3.0/5 (1 vote cast) The Macrogalleria -- A Cyber Wonderland of Polymer Fun   by Dept. of polymer science, U. of Miss. Details This site is devoted to analysis of polymers and focuses on SEC, although links to other techniques are provided. It does not go into great detail, but provides a nice overview of critical ideas behind SEC. The link to molecular weight distributions may alos help some students with the concepts behind polymers and polymer analysis. It is written simplistically and in an informal manner, which may put some people off, but others might enjoy it for this reason. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) NMR animation   by Françoise Sauriol Details This site has very nicely animated tutorials on NMR with sufficient depth to be useful to the non NMR savy. The animations are accompanied by short descriptions so that the processes displayed can be understood by the viewer. This site goes beyond just showing precession. There are nice animations showing the effect of different pulses, including composite pulses on the magnetization, the effects of magnetic gradient pulses to measure diffusion and do coherence pathway selection. Other aspects are less useful since they basically just present material that could be found in a book in an animated format. The site is useful for teaching in a lecture setting. Students will find the images appealing. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Understanding NMR   by james keeler Details This site provides links to a series of pdf files that represent chapters of an e-text on the basics of NMR. While many textbooks on NMR are available the chief merit of this one is that it has a nice chapter on the NMR instrument (ch. 5) which should be accessible to undergraduates. The text also provides a relatively mathematics-free or maybe more accurately Dirac bracket notation-free introduction to 1-D and 2-D (COSY and NOESY) experiments that would be appreciated by advanced undergraduates or beginning graduate students involved in undergraduate research experiences using NMR Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) EPR Basics and Application to Biology   by Thomas Prisner, University of Frankfurt Details This site contains a set of powerpoint slides that discusses the basic principles underlying electron paramagnetic resonance (EPR). The slides also present examples of the application of EPR to biological systems including organic radicals in proteins, paramagnetic metal centers and spin labels. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Spectroscopy   Details This site describes the theory and practice of IR and NMR spectroscopy for classroom and laboratory instruction. Although it is written for a course at the University of Colorado, Boulder, this site is appropriate for anyone doing analytical measurements with infrared or NMR. Currently 3.00/5 1 2 3 4 5 Rating: 3.0/5 (1 vote cast) Organic Chemistry On Line   by William Reusch Details This site covers introductory material related to the analysis of small organic molecules by mass spectrometry, UV-visible, IR, and NMR spectroscopy. A concise explanation of each approach is presented with illustrations. This would be useful for those teaching organic chemistry and for others who need a review of the topic. The section on Spectroscopy Resources at the end of the site contains a list of links to additional information plus a several links to compilations of problems (and their solutions) that challenge the student to interpret NMR or IR spectra. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) PC Software for NMR, IR   by Bell, Harold M. Details This web site allows readers to download a variety of PC-based NMR simulation programs. NMRSM is for the calculation of spin-spin coupling patterns, the program FTNMR Simulator simulates the operation of a high field spectrometer and the program FIDMAKER allows the user to create FID's for subsequent analysis by students. Although these simulation programs are fairly limited in their scope, they will be useful for faculty at institutions that do not have access to a modern Fourier transform NMR spectrometer. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) NMR Spectroscopy   by Shattuck, Thomas W. Details This site contains web-based programs that allow the user to predict chemical shifts, spin-spin coupling patterns and NMR line shapes affected by dynamic chemical exchange. This site will be most useful for students with a good background in the fundamentals of NMR theory. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) WebSpectra - Problems in NMR and IR Spectroscopy   by Merlic, Craig A. Details This web site provides thirty beginning, twenty-nine intermediate, and sixteen advanced NMR structure analysis problems and their solutions. For every unknown a proton and a carbon spectrum are provided. Many of the more advanced problems contain COSY and DEPT spectra as well. A particularly useful feature of this site is that the user can zoom into spectral regions in all of the spectra. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) The Basics of MRI   by Hornak, Joseph Details This website is an on-line textbook describing the principles of magnetic resonance imaging (MRI). The treatment is often quite mathematical, but the site also reviews all of the mathematics and physics needed to understand the material. Approximately forty clinical images can also be found on the site. This site is appropriate for students needing a stand-alone introduction to MRI. Currently 5.00/5 1 2 3 4 5 Rating: 5.0/5 (1 vote cast) CHEM 525 NMR Spectroscopy   by de Dios, Angel C. Details This site provides both classical and quantum mechanical descriptions of NMR. Some nuts and bolts aspects of NMR and the basics of two-dimensional spectroscopy are also covered. This web site should be informative for graduate students or professionals seeking a more thorough understanding of the basic principles underlying NMR spectroscopy. Currently 4.00/5 1 2 3 4 5 Rating: 4.0/5 (1 vote cast) Molecular Structure and Dynamics by NMR Spectroscopy   by Edison, Arthur S. Details This site provides PowerPoint slides for a series of lectures for a graduate-level course in NMR spectroscopy. While the casual student may find it hard to follow everything on the slides without an accompanying lecture, the Power Point files should be very useful for advanced students or educators putting together similar courses. Mathematica documents that allow one to perform matrix algebra and Fourier transforms are also provided. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) NMR Spectroscopy - Theory   by Lord, J.R. Details This web site begins with a simple quantum description of NMR and proceeds to introduce resonance absorption, relaxation, chemical shifts, and scalar couplings. This site will be useful for advanced undergraduate students needing a description of NMR that is more detailed than that given in most introductory Organic texts. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) 2D NMR Spectroscopy   by Bria, Marc Details This site provides a concise, but thorough introduction to NMR spectroscopy with a focus on 2D NMR. This site will be most useful for students with some introductory background in NMR. The basic principles of common 2D NMR experiments are presented and illustrated with spectra. Instructors wanting to illustrate the appearance of a TOCSY, NOESY, or COSY spectrum to an undergraduate class will also find useful information on this web site. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Organic Structure Elucidation Workbook   by Smith, Bradley D. Details This web site contains 64 structure elucidation problems for the qualitative analysis of organic compounds. For each problem the empirical formula, molecular weight, 500 MHz proton and 125 MHz carbon NMR spectra, IR and mass spectral data are presented. The problems are categorized as easy, moderate or difficult. Students in introductory Organic Chemistry who want practice identifying unknown compounds should find this site useful. Instructors looking for exam or classroom problems for students at this level could also take advantage of the information on this site. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Basics of NMR   by Hornak, Joseph P. Details An online text on the basics of Nuclear Magnetic Resonance (NMR) spectroscopy. The text contains information especially appropriate for the novice, but topics are treated at sufficient depth to be useful for more advanced students. This resource features animations that illustrate complex NMR concepts such as precession and the rotating frame of reference. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Integrated Spectral Database System for Organic Compounds   by Kinugasa, S. Details Searchable database of infrared, NMR, and mass spectra of organic compounds. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast)   * editor's choice  Analytical Chemistry 2.0   by David Harvey Details A complete textbook for Quantitative Analysis is freely downloadable. Teach yourself Analytical Chemistry, or be part of a class on the subject. Currently 5.00/5 1 2 3 4 5 Rating: 5.0/5 (2 votes cast) Kinetic Capillary Electrophoresis(KCE): A conceptual Platform for Kinetic Homogeneous Affinity Methods   by Sergey N. Krylov Details Kinetic Capillary Electrophoresis is a family of methods for studying binding of biopolymers, measuring rate constants, binding constants, and in some cases providing mechanistic details. This annimation illustrates several kinetic CE modes and their effect on the complex formation and dissociation. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Affinity Chromatography   by Sapna Deo Details Using exposition, graphics, and commercial videos, this module teaches the theory and application of affinity chromatography in the characterization of proteins, nucleic acids, and other biochemical/biomedical systems. Problems and application examples support the tutorial material. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) RSC.org: Gas Chromatography   by The Royal Society of Chemistry- Univ.Warwick Details This video, distributed on YouTube by the Royal Society of Chemistry is on the basic principles of GC. This video is a short primer (~5 min) which introduces the technique and instrumentation. There are many assumptions that are made in the presentation of this material, due to the fact the video is meant to be a basic introduction. Examples of such assumptions include the statement that volatility solely controls the elution order of volatile compounds on a GC column and that concentration is the only parameter that controls the relative response of a compound for a given GC detector. The ultimate strength of this video is the general nature of the content that makes it appealing to a wide audience. The video may be most appropriate in a lower-level general education science course (i.e forensic science) or as a quick orientation video for instrumental analysis students. The GC-FID and GC-MS are highlighted. Currently 3.00/5 1 2 3 4 5 Rating: 3.0/5 (1 vote cast) Gas Chromatography Video   by Frank Dunnivant, Whitman College, Education Solns Details This is a high quality video module demonstrating the basics of gas chromatography. Highlights include different GC instruments, detectors etc., as well as unique topics such as trouble shooting and interfacing the column that are not addressed in standard texts. This resource can be run (Shockwave Flash) from the home server or downloaded to your computer. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) HPLC Tutorial 2,0 Video   by Frank Dunnivant, Whitman College, Education Solns Details This high quality video resource focuses on partition chromatography. The video presents an overview of basic separation theory and discusses instrumentation and data analysis. The size of the video (62.6 MB) almost requires a high speed internet connection. The resource can be downloaded to the user's computer, which is recommended for those with slower connections. Currently 4.50/5 1 2 3 4 5 Rating: 4.5/5 (2 votes cast) LC/GC magazine   by LC/GC Details LC/GC magazine is a very good source for relatively short articles about fundamental chromatographic issues as well as applications. The content is appropriate for both introdcutory analytical courses (e.g. quant) and for instrumental analysis courses. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Ion Exchange Chromatography   by Paul A. Craig Details This website contains an ion chromatography simulator that can be run on-line or can be downloaded. The simulator focuses on separations of proteins using Ion Chromatography. Also included is hyperlinked reference information, an example of a homework assignment using the simulator, and some information on protein structures.(note this is an archived version of this site, as the original has been moved). Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) RLM Synge Nobel Prize Lecture   by Nobel e-Museum Details This site describes the applications of partition chromatography. The pedagogical value lies in its historical perspective and in its description of the early applications of partition chromatography. This site provided a unique historical perspective on the applications of partition chromatography and one of the pioneers of the technique. This document also contains many relevant figures and graphics. Currently 5.00/5 1 2 3 4 5 Rating: 5.0/5 (1 vote cast) AJP Martin Nobel Prize Address   by Nobel e-Museum Details This site describes the historical development of partition chromatography. The pedagogical value lies in its historical perspective rather than its description of partition chromatography. This site provided a unique historical perspective on the development of partition chromatography and one of the pioneers of the technique. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Vydac Application Notes Online   by Vydac Details Short application notes and technical information pertinent for Vydac products. Application and trouble-shooting information for separations of peptides, proteins, oligionucleotides and carbohydrates using liquid and ion-exchange chromatography. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Fundamentals of GC/MS   by Shimadzu Europa GmbH Details This tutorial provides an excellent introduction into the fundamentals of GC/MS. The tutorial consists of five sections: An introduction of mass and types of ions, ionization modes, hardware, figures of merit describing mass analyzer performance, and qualitative methods of GC/MS analysis - including library searches. Each section contains animations or simulations of chemical and physical interactions that pertain to mass spectrometry such as gas-phase ionization processes, fragmentation, mass analyzers, the importance of a vacuum, and detectors. A basic introduction to gas-liquid chromatography is also provided. The tutorial is intended to describe GC/MS at an introductory level, but does include theory at an intermediate level, which may be included or not depending on the intended audience. Information is presented in a Powerpoint style, and each figure has a Details tab which provides additional information on the subject. This website has excellent pedagogical value for students and new practitioners. Currently 3.00/5 1 2 3 4 5 Rating: 3.0/5 (1 vote cast) Gas Chromatography Application Notes   by Robertshaw, Nick Details Application notes from 2000-2005 presented at conferences (the conferences are not identified listied by year). Applications could serve as a source of experiments for advanced teaching labs and also assist those interested in solving analytical problems that involve separations. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Applications Searchable Site   by Waters Corporation Details This site is a search engine for chromatographic and mass spectral methods in the Waters Corporation database. It searches based on analyte. It pulls up refereed journals(citations only) and company literature (pdf format). The site claims 23,500 documents. The site will be useful to those looking for methods in chromatography, including faculty and students looking for project ideas for either research or laboratory experiments. Currently 1.00/5 1 2 3 4 5 Rating: 1.0/5 (1 vote cast) Reversed phase column characteristics and general chrom. overview   by Waters Details This is a link within the Waters HPLC Primer site. It contains very useful details regarding the properties of HPLC packing materials and how they impact performance. Since it is part of a larger site, it contains links to other information provided by waters on other aspects of HPLC as well as MS and other techniques. There is a higher level of detail in the instruction here than in most general sites discussing HPLC. Also, the site shows which Waters columns contain the different kinds of packing materials described, which would be helpful to a lot of people. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Pierce Biotechnology   by Pierce biotechnology Details The pedagogical value lies in its concise description of the various analytical derivatization reactions and reagents used for gas chromatography. This site gives a nice description of the various derivatization reagents and what type of analyte they are used for. One of the few, if not the only, ASDL sites dealing with derivatization. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Chemical Separations   by James K. Hardy Details This site contains complete notes in a PowerPoint-like presentation for a chemical separations course. It covers a wide variety of topics, including distillation, extraction, gas chromatography, liquid chromatograpy, chromatography theory, instrumentation, electrophoresis, field flow fractionation, and affinity chromatography. It covers these topics thoroughly using a clear, consistent, and simple presentation style. Links to major topics like GC, LC, and electrophoresis provide specific information about the theory, instrumentation, and practice related to these techniques. The site also contains many annimations illustrating important separation processes. Currently 3.00/5 1 2 3 4 5 Rating: 3.0/5 (1 vote cast) Animation of diode array detection in HPLC   by TRSL Details This animation site deals specifically with diode array detection for liquid chromatography. The animations are short (one to two minutes) and can easily be shown in class as part of a lecture. They are extremely helpful in illustrating key components and concepts of chromatographic systems. Users are encouraged to explore the site and the other brief animations as well. Separate links to other simulations by the same company (TRSL) are also listed on ASDL. This site requires FLASH version 7 or higher in order to work properly. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Craig countercurrent extraction machine applet   by Prof. C.E. Efstathiou Details This site provides a useful applet that demonstrates countercurrent extraction. The explanation of the method is short, but good. The level is appropriate for undergraduate students. The Applet itself is well designed and provides a useful exercise for students around which homework or small-group waork could be developed. The use of color is particularly helpful. The same author has a larger collection of applets about instrumentation and other analytical concepts in the ASDL collection. It can be found by searching the ASDL library using 'applets' as the keyword, or going to the site: http://www.chem.uoa.gr/applets/Applet_Index2.htm Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Gas Chromatography experiment   by Wayne E. Steinmetz Details This site provides a Word document that describes a GC experiment involving the separation and quantitation of four butyl alcohol isomers. It has a complete background about the components of a GC instrument (with labeled pictures) and their functions. It has a section devoted to the measurement of response factors of the detector in use (here an FID). This would be a good experiment for a new faculty member to use as is, with slight modification to make it relevant to the particular GC system to be used. Currently 4.00/5 1 2 3 4 5 Rating: 4.0/5 (1 vote cast) Paper Chromatography of Stains   by Virzi, Frank Details A paper chromatography experiment separating dyes. The experiment is targeted toward 8-12 grades, but could be suited to an introductory chem laboratory section.The text of the site contains instructions for setting up and executing the experiment in a large class setting. Currently 1.00/5 1 2 3 4 5 Rating: 1.0/5 (1 vote cast) Rheodyne - Application Support   by Nine Trees Design Details Application notes, technical information, and on-line trouble-shooting guide pertinent for Rheodyne products (high-pressure valves). Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Selerity Technologies Application Notes   by Selerity Technologies Details Applications and tutorials related to supercritical fluid chromatography and temperature programming in liquid chromatography (PDF). Application area is mainly petrochemicals. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Chromatography Nomenclature and Definitions   by IUPAC Details This website gives the IUPAC approved definitions in the field of chromatography. It is critical for students to appreciate the importance of using standardized nomenclature and definitions. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Chromatography Theory   by Thomas Hardy Details James Hardy has produced a number of powerpoint type lecture modules for analytical chemistry. This is another very good module that covers the introductory theory of chromatography. Includes chromatography types, plate and kinetic theories. Level of presentation is at the introductory analytical chemistry level. It is a colorful and well planned presentation of the introduction to chromatography that could be used as the basis for lectures on chromatography at the introductory analytical chemistry or instrumental analysis level. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) HPLC, LC-MS, and FTIR sites   by Shula Levin Details This site contains a considerable amount of information on HPLC, LC-MS, and FTIR via linked sites by the same author and some vendor sites. It may require considerbale time to follow the links to find specific information, but as a collection of sites related to HPLC and FTIR it is quite useful as a teaching resource. There are some interesting animations that might be helpful for students to understand how these instruments work. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Chemistry-Based QuickTime Movies, Animations, and Streaming Audio   by Chasteen, Thomas G. Details Downloadable animations and movies for analytical instruments and processes. Formats in QuickTime, GIF animations, and Flash animations. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Paper Chromatography   by Reeves, James H. Details A site with animation that provides a very brief introduction to the idea of separation of components in a mixture and a set of instructions for students for separating colored compounds by paper chromatography (on coffee filters). The appropriate audience would be students in a high-school or introductory, non major's college chemistry class. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Learning to Learn: An Introduction to Capillary Electrophoresis   by Mabrouk, Pam Details This article describes a problem based learning approach to analytical chemistry labs using capillary electrophoresis as the instrumental method. The on-line link requires a password for The Chemical Educator to get the full article. The article also describes a lab that is an example of problem based learning. Students, playing the role of lab technicians, learn how to use the instrument in order to perform an analysis. Currently 1.00/5 1 2 3 4 5 Rating: 1.0/5 (1 vote cast) Micro Separations Distance CE   by L. A. Holland, C. M. White, K. M. Hansen Details This site describes how to assemble an inexpensive, yet reliable capillary electrophoresis apparatus and provides experiments to demonstrate electrodynamically-driven separations. Good background material about CE theory is provided. Currently 4.00/5 1 2 3 4 5 Rating: 4.0/5 (1 vote cast) Custom Designed HPLC Couse for Teva Abic   by Dr. Shulamit Levin Details This site contains slides to accompany lectures in HPLC. They do not contain enough description for the average student to follow. However, they provide a lot of excellent information about practical aspects of HPLC. The sections on troubleshooting, sample preparation, gradients, system peaks, system suitability and methods validation are particularily valuable. The illustrations and diagrams are informative but occasionally difficult to read because of their resolution. Applications and examples are very good. This site is a subset of Dr. Levin's larger site related to teaching separations and other analytical topics, but a link to her home page is provided. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) HPLC Primer   by Waters Corporation Details Nice introduction to high performance liquid chromatography that includes information on the modes of separation, a comparison of normal vs. reversed phase separations, identification of analytical, semi-prep, and preparative scale LC and a very nice large glossary that includes definitions of terms related to chromatography. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Exclusion Chromatography   by Kimball, John W. Details This site contains a brief description of the separation mechanism in size exclusion chromatography. The picture helps visualize the separation, but is a simplified and idealized presentation. A companion site, http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/A/AffinityChrom.html, describes affinity chromatography. The two sites together may be helpful in a biochemistry course where such techniques are used or discussed. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Chromatography theory and modes   by Terry Frey Details This site is an introductory lecture in outline form about chromatography. It appears directed toward biochemical separations. The coverage is broad but not deep. Discussions of counter-current separations, gel permeation, and ion exchange are accompanied by some mention of partition, paper, and gas chromatography Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Origin of Chromatography   by Lisensky, George Details This site has a series of links to QuickTime movies that animate the chromatographic process. The movies show the effect of changing K, L, and N on peak width and separation. The site is useful in combination with other sources that explain the background theory. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) GC/MS with animations   by Dr. Thomas G. Chasteen Details This site contains a good review of GC detectors that is linked to animated files describing the hardware and principles of operation for GC/MS. From this site, one can also get to multiple other animations about a variety of analytical topics. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Chromatography   by Hardy, James K. Details This site provides fundamental background information about chromatogaphy, including plate theory, rate theory, the meachanisms of separations, and qualitative and quantitative aspects of chromatography. The format is a PowerPoint-like presentation. It is a subsite of a larger, broader site about chemical separations (http://ull.chemistry.uakron.edu/chemsep/index.html). The combination of all of the related sites is quite nice and students will find them useful. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Gas Chromatography   by Dr. Thomas G. Chasteen Details This site contains a brief introduction to the concepts of injection and detection in gas chromatography, focusing on the split/splitless injection port and flame ionization detectors. The treatment is similar to that in analytical chemistry textbooks. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) The HPLC Doctor   by de Neves, H. J. Chaves Details This site provides HPLC troubleshooting tips. It covers common separation problems such as peak fronting or tailing and split peaks and suggests solutions. This site will be most useful for students and practitioners who already have some background knowledge of separation theory. It will be especially helpful for laboratory or research students who are developing a new separation method or are encountering problems with their chromatographic experiments. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Paper Chromatography of Dyes in Foods   by Ann VanBlaricum Details This site about paper chromatography is organized and the information is presented well -- perhaps making it one of the better sites about paper chromatography. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) GC books   by Scientific Instrument Services Details This site contains a list of books about gas chromatography with their tables of contents. Potentially useful for practictioners or research students needing an introduction to GC. Some links (such as those to spectroscopy, NMR, and LC) do not yield any useful information. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Chromatography Theory   by Rochester Institute of Technology Details This site contains standard definitions related to chromatgraphy similar to treatments found in analytical textbooks. It introduces the beginning student to LC concepts relevant to biochemistry and includes a good example of choosing a mobile phase pH for a protein separation based on ion exchange. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Chrom. and Electrophoresis experiments with PDFs   by CENTER for CHEMISTRY EDUCATION Details A site with PDF links to several slab gel electrophoresis, HPLC, and GC experiments intended for high school or college audiences. This site may provide a useful starting point for faculty seeking to implement new laboratory experiments based on these techniques. A login (email address) is required, but once logged in, follow the "Free Resources" link to see many instrumental and analytical experiments that have been submitted to the site. Currently 3.00/5 1 2 3 4 5 Rating: 3.0/5 (1 vote cast) Gas Chromatography   by Environmental Protection Agency Details This EPA site provides a brief overview of EPA remediation methods and projects. The links "Remediation" and "Characterization and Monitoring" have sub-links that provide analytically relevant materials. Many applications and case-specific studies are presented. Many of the links are related to sampling statistics. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) LC Calc (TM) Online. A handy calculator for HPLC computations.   by Mark Earll Details This site contains several on-line calculators for use in liquid chromatography. These include pressure unit conversion, buffer pH, and scale-up factors. Some links may be broken. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) The Macrogalleria -- A Cyber Wonderland of Polymer Fun   by Dept. of polymer science, U. of Miss. Details This site is devoted to analysis of polymers and focuses on SEC, although links to other techniques are provided. It does not go into great detail, but provides a nice overview of critical ideas behind SEC. The link to molecular weight distributions may alos help some students with the concepts behind polymers and polymer analysis. It is written simplistically and in an informal manner, which may put some people off, but others might enjoy it for this reason. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Kinetic Capillary Electrophoresis(KCE): A conceptual Platform for Kinetic Homogeneous Affinity Methods   by Sergey Krylov Details Kinetic Capillary Electrophoresis is a family of methods for studying binding of biopolymers, measuring rate constants, binding constants, and in some cases providing mechanistic details. This Online Article is a presentation by the originators of this family of techniques ready for classroom or independent use. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Chromatography and Mass Spec Lectures   by Prof. Jose-Luis Jimenez , U. Colorado Details This site contains mass spectrometry and chromatography lecture notes for a graduate course. They are subdivided by topic (history, theory, etc.) and are easy to browse. They may be helpful to someone constructing their own course in chromatography and/or mass spectrometry. The notes are fairly complete. The historical sections may particularly save time in preparing courses. The notes also provide good information and a helpful outline to follow. The site also has some nice mass spectrometry animations from Thermo. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Liquid Chromatography Books   by isbn.nu website Details This site provides a list of books related to liquid chromatography and its applications. While not immediately pedagogically useful, it may be useful to those seeking texts about LC for their own research interests or to provide as references to students. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Macherey-Nagel Product Catalog   by Wieczorrek, Carsten Details Database with references for nearly 3000 separation applications. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Introduction to Capillary Electrophoresis   by Beckman Coulter Details A comprehensive overview of capillary electrophoresis and its closesly related variants. This pdf document details both theoretical and practical aspects of CE, and includes an application index and thorough bibliography. This material is appropriate for beginners or new practitioners of CE, and would be an excellent resource for instruction in instrumental techniques. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) SGE Chromatography Products - Troubleshooting and Training   by SGE Webteam Details A guide to troubleshooting chromatography problems, especially GC. There is also material on increasing column efficiency and reference material on properties of stationary phases. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Chromatography   by Tissue, Brian M. Details Multiple links in a broad discussion of several facets of chromatography - including theoretical and instrumental aspects. Five modes of chromatography are highlighted: GC, HPLC, LC, SEC and TLC. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Surface Acoustic Wave/Gas Chromatography System for Trace Vapor Analysis   by U.S. Department of Energy Details A cost analysis and progress report to the Federal Government's Department of Energy detailing the use of a surface acoustic/wave gas chromatograph for trace vapor analysis. It contains a brief description of surface acoustic wave (SAW) detectors used with gas chromatography. This site is a good example of the detailed reports chemists and engineers might put together to obtain or continue to get funding. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Capillary electrophoresis movie   by Thomas Chasteen Details This website is an animation describing aspects of CE separations, including electroosmotic flow, the separation, injection (hydrodynamic and electrophoretic) and detection (direct and indirect). Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Chromatography books   by isbn.nu website Details This site simply offers books covering a wide range of both general and specific topics related to gas chromatography and its applications. While not of immediate pedagogical value, it may be useful to those looking for good texts about gas chromatography either for their own research needs or to provide as resources to their students. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Separation Science Animations   by TRSL Details This site from TRSL is the main site that links to many animations related to how chromatography systems work. Most of the animations are quite good and would be helpful to students when trying to visualize what occurs in an instrument during an separation (e.g. injection, detection, etc.). Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Landmark Instruments of Chemistry   by Richard H. Bromund Details This website effectively uses animated movies combined with text explanations to describe the processes in FT-IR interferometry, TLC, GC and magnetic sector mass spec. It is effective in illustrating processes that are otherwise difficult to visualize. These materials are excellent visualization tools that can be incorporated into lectures readily. Currently 4.00/5 1 2 3 4 5 Rating: 4.0/5 (1 vote cast) Reverse Phase HPLC Basics for LC/MS   by Ion Source, LLC Details This site provides a tutorial on practical reverse phase chromatography for LC-MS. Focusing on peptide and protein analysis, Andrew Guzzetta offers appropriate tips on mobile phase gradients, preparing your reversed-phase HPLC column for the first run of the day, and taking care of your column after the day's separations are complete. The site also provides a representative list of web-based resources on LC. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) CASE TEACHING NOTES for Filthy Lucre   by Ed Acheson Details The website presents a case study involving the detection of cocaine on dollar bills. The case study uses GC-MS, but has an introduction appropriate for beginning chemistry students. Currently 2.00/5 1 2 3 4 5 Rating: 2.0/5 (1 vote cast) Animation of sample loop HPLC injections   by TRSL Details This site deals specifically with sample loop injections in liquid chromatography. The animations are short (one to two minutes) and can easily be shown in class as part of a lecture. They are extremely helpful in illustrating key components and concepts of chromatographic systems. Users are encouraged to explore the site and the other brief animations as well. Separate links to other simulations by the same company (TRSL) are listed below. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Capillary electrophoresis: a versatile family of analytical techniques   by Biotechnology and Applied Biochemistry Details This site contains a review article covering capillary electrophoresis and variations thereof. The material presented is largely similar to that which can be cfound in textooks or primers, but this is in a nice condensed version. As the author states, the article "reviews basic principles behind the technique and the range of options which allow the same instrument to be used for the separation and analysis of a wide range of analytes from large biomolecules, such as proteins and nucleic acids, to metal and organic ions while having the capability to resolve enantiomers and non-charged molecules." Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Animation of Dual Head HPLC Pump   by TRSL Details This animation site deals specifically with dual head LC pumping. The animations are short (one to two minutes) and can easily be shown in class as part of a lecture. They are extremely helpful in illustrating key components and concepts of chromatographic systems. Users are encouraged to explore the site and the other brief animations as well. Separate links to other simulations by the same company (TRSL) are also listed on ASDL. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Animation of Quadrupole GC-MS detection   by TRSL Details An animation site which deals specifically with quadrupole mass spectrometry detection for chromatography. The animations are short (one to two minutes) and can easily be shown in class as part of a lecture. They are extremely helpful in illustrating key components and concepts of chromatographic systems. Users are encouraged to explore the site and the other brief animations as well. Separate links to other simulations by the same company (TRSL) are also listed on ASDL. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) An Unusual Arson Case: Polymer Grains   by Gino Van Vaerenbergh Details A case example of determination of an arson accelerant by a variety of analytical techniques. Will make a good case record for an active learning class. Uses a variety of techniques, particularly chromatography and headspace analysis. Currently 3.00/5 1 2 3 4 5 Rating: 3.0/5 (1 vote cast) Animation of GC solvent focusing   by TRSL Details This site has very good animations related to separations. It deals specifically with solvent focusing in gas chromatography. The animations are short (one to two minutes) and can easily be shown in class as part of a lecture. They are extremely helpful in illustrating key components and concepts of chromatographic systems. Users are encouraged to explore the site and the other brief animations as well. Separate links to other simulations by the same company (TRSL) are also listed on ASDL. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Chemiluminescence for Chromatography   by Dr. Thomas G. Chasteen Details This site is a brief description of chemiluminescence detection for chromatography. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Basic Liquid Chromatography   by Kazakevich,Yuri Details A complete textbook of liquid chromatography by Yuri Kazakevich and Harold McNair on the Web. Extraordinarily comprehensive in its coverage of fundamental chromatographic theory and instrumentation for a website. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Affinity Chromatography   by DiResta, Dan Details This is an experiment showing the application of affinity chromatography to the separation of albumin from horse serum. A brief introduction of affinity chromatography and how it is being used in this specific experiment is given. This appears to be a good experiment to show the advantages of affinity chromatography in separating specific proteins from a complex matrix and would be useful in a biochemistry course or a course that is specifically looking at differing types of chromatography. Currently 4.00/5 1 2 3 4 5 Rating: 4.0/5 (1 vote cast) Analytical Instruments and Spectroscopic Concepts   by Chasteen, Thomas G. Details Primers for different analytical techniques (HTML, PDF). Also links to animations and audio descriptions of analytically related concepts. Techniques include atomic absorption, spectrophotometry, chemiluminescence, gas chromatography, mass spectrometry, and atomic emission. Currently 1.00/5 1 2 3 4 5 Rating: 1.0/5 (1 vote cast) Capillary Electrophoresis Primer   by MicroSolv Details This site presents a primer on capillary electrophoresis. This is a very complete treatment covering the basic theory of CE, sample stacking techniques, and practical information about optimizing CE separations. There is an animation showing how to properly cut a capillary and a glossary of terms for analytical validation. The site provides theory and background to CE but perhaps not as in as much depth as an introductory instrumentation text. On the other hand it has a large range of practical tips that a student would not necessarily get from a text. The link to "Helpful Hints for Improved Capillary Electrophoresis" which includes a section on selection of buffers, tables of buffer pKa's, buffer additives, conditioning capillaries and troubleshooting problems. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Chromatography   by Dan Damelin Details An introductory site about chromatography that does not go into great depth. However, the simulation of paper chromatography is worth exploring with students as it illustrates that the separation of compounds relies on the difference in the solutes affinities for the mobile phase relative to the stationary phase. Because of its apparent simplicity, this simulation has significant pedagogical potential and could be used in a variety of ways in class to explore the factors governing chromatographic separations. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Polymeric matrices for DNA sequencing by capillary electrophoresis   by Methal N. Albarghouthi and Annelise E. Barron Details This article reviews a variety of polymer types that have been used for both single and double stranded DNA separations. Comparisons are made in terms of the length of sequences that can be accurately read, the viscosity, ease of column filling, matrix stability, separation time and conditions for optimum resolution. These details are not likely available in another single source. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Detection of Arson accelerants   by Thomas Brettell Details Analysis of arson with detailed information on quality control and methods of transfer, excellent sample chromatograms. Could be used as a problem based learning tool. Illustrates important aspects of headspace analysis Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Chem 212 - Separations Science   by Thomas Wenzel Details Superb website providing instructional materials in support of a problem-based learning approach to Quantitative Analysis (equilibria and separations). Materials available include textbook chapters, in-class, and out-of-class problems, a peer/peer evaluation tool, and a handout in support of a final course lab project report. The majority of materials are provided in an Adobe pdf format - very helpful for adoption by interested faculties. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Animation of single wavelength UV-vis detection for HPLC   by TRSL Details This site deals specifically with single wavelength UV-vis detection for liquid chromatography. The animations are short (one to two minutes) and can easily be shown in class as part of a lecture. They are extremely helpful in illustrating key components and concepts of chromatographic systems. Users are encouraged to explore the site and the other brief animations as well. Separate links to other simulations by the same company (TRSL) are also listed on ASDL. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) GC coating animation   by TRSL Details This site is one in a series of sites with very good animations related to separations. This animation deals specifically with solute retention in GC. The animations are short (one to two minutes) and can easily be shown in class as part of a lecture. They are extremely helpful in illustrating key components and concepts of chromatographic systems. Users are encouraged to explore the site and the other brief animations as well. Separate links to other simulations by the same company (TRSL) are also listed on ASDL. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Animation of GC flame ionization detector   by TRSL Details This site is one in a series of sites with very good animations related to separations. This animation deals specifically with flame ionization detection in GC. The animations are short (one to two minutes) and can easily be shown in class as part of a lecture. They are extremely helpful in illustrating key components and concepts of chromatographic systems. Users are encouraged to explore the site and the other brief animations as well. Separate links to other simulations by the same company (TRSL) are also listed on ASDL. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Fluorescence Detection Animation   by TRSL Details This animation site deals specifically with fluorescence detection for liquid chromatography. The animations are short (one to two minutes) and can easily be shown in class as part of a lecture. They are extremely helpful in illustrating key components and concepts of chromatographic systems. Users are encouraged to explore the site and the other brief animations as well. Separate links to other simulations by the same company (TRSL) are also listed on ASDL. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Animation of Single Head Check Valve HPLC Pump   by TRSL Details This animation site is specifically about reciprocating pumps for liquid chromatography. The animations are short (one to two minutes) and can easily be shown in class as part of a lecture. They are extremely helpful in illustrating key components and concepts of chromatographic systems. Users are encouraged to explore the site and the other brief animations as well. Separate links to other simulations by the same company (TRSL) are also listed on ASDL. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) GC Electron Capture Detector Animation   by TRSL Details This site is one in a series of sites with very good animations related to separations. This animation deals specifically with electron capture detectors. The animations are short (one to two minutes) and can easily be shown in class as part of a lecture. They are extremely helpful in illustrating key components and concepts of chromatographic systems. Users are encouraged to explore the site and the other brief animations as well. Separate links to other simulations by the same company (TRSL) are also listed on ASDL. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Split Injection GC   by TRSL Details This animation site deals specifically with split injection in gas chromatography. The animations are short (one to two minutes) and can easily be shown in class as part of a lecture. They are extremely helpful in illustrating key components and concepts of chromatographic systems. Users are encouraged to explore the site and the other brief animations as well. Separate links to other simulations by the same company (TRSL) are also listed on ASDL. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Animation of pulse dampner in HPLC   by TRSL Details This animation site deals specifically with pulse dampners is LC and could help in a general lecture about LC pumps. The animations are short (one to two minutes) and can easily be shown in class as part of a lecture. They are extremely helpful in illustrating key components and concepts of chromatographic systems. Users are encouraged to explore the site and the other brief animations as well. Separate links to other simulations by the same company (TRSL) are also listed on ASDL. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) GC Splitless Injection Animation   by TRSL Details This site is one in a series of sites with very good animations related to separations. This animation deals specifically with splitless injection in GC. The animations are short (one to two minutes) and can easily be shown in class as part of a lecture. They are extremely helpful in illustrating key components and concepts of chromatographic systems. Users are encouraged to explore the site and the other brief animations as well. Separate links to other simulations by the same company (TRSL) are also listed on ASDL. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Adsorption and Chromatography in Bioseparations   by Hubble, John Details This material was developed for a final year undergraduate bioseparations module. There are a number of links to sites for modeling adsorption chromatography. For example, a link to an Excel spreadsheet provides a demonstration of varying N, l, and K (or alpha)affect band separation. Other links explain adsorption isotherms in the context of bioseparations. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Analytical Chemistry   by Hardy, James K. Details Lecture notes for 1st semester are on titrations, gravimetry, kinetics and electrochemistry (redox). Potentiometry, coulometry, voltammetry, spectroscopic and separation methods are presented during 2nd semester, illustrated with QuickTime animations. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Mass Spectrometry for Chromatographers   by Hardy, James K. Details This short course looks at mass spectrometers as detectors for gas chromatography. Includes instrumentation, spectral interpretation, data collection, worked problems, and a knowledge quiz. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast)   * editor's choice  Analytical Chemistry 2.0   by David Harvey Details A complete textbook for Quantitative Analysis is freely downloadable. Teach yourself Analytical Chemistry, or be part of a class on the subject. Currently 5.00/5 1 2 3 4 5 Rating: 5.0/5 (2 votes cast) Introduction to Lasers   by Carol Korzeniewski Details Lasers are preferred light sources for high resolution or time-resolved optical spectroscopy. This module introduces the workings of lasers and gives examples of common designs. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Tunable Monochromator Movie   by Thomas G. ChasteenChasteen Details This Quick Time movie illustrates and describes to operation of a Czerny-Turner monochromator. The slits, mirrors, grating and grating scan are described in the production of a specific wavelength at the outlet slit. The movie is a companion to the double beam spectrometer animation. Currently 1.67/5 1 2 3 4 5 Rating: 1.7/5 (3 votes cast) RSC.org: UV/Vis Spectroscopy   by The Royal Society of Chemistry- Univ. Warwick Details This video distributed on YouTube is on the basic principles of UV/Vis. Provides a good primer (~5 min), and the “top-off” look of the instrument is useful in explaining components. A double beam instrument is described. Currently 4.00/5 1 2 3 4 5 Rating: 4.0/5 (1 vote cast) RSC.org: IR Spectroscopy   by The Royal Society of Chemistry-Univ. Warwick Details This video on YouTube covers the basic principles of infrared spectroscopy. Very useful for a newcomer to IR. This video of 6.5 minute would be useful in a classroom setting or students interested in the technique. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Optical Tweezers: Measuring Piconewton Forces   by Mark Williams Details This is a comprehensive reference article for optical tweezers technology. It outlines application of this technique in the piconewton force measurement for biological samples. The article includes principle of the technique, calibration, and examples of the use of this technique in one single article. The paper is easy to read, self-contained, and complete. It supplies a good mix of theory and application, with interesting descriptions involving measurements with RNA and DNA. One needs to have a basic background in physics and biology to understand the theory and applications. The article is written at the senior level for undergraduates as well as graduate students. The content is acceptable for ASDL. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Atomic Emission Spectroscopy   by Alexander Scheeline Details A learning module that explains the instrumental systems and interactions involved in atomic emission for elemental analysis. Completion of the module will leave the learner with knowledge of optics, plasma sources, and trade-offs in choosing the right instrument for a given analytical task. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Atomic Spectroscopy in a Project-Based Lab   by Dulasiri Amarasiriwardena Details An article published in the "ABCs of Teaching Analytical Science" series of the journal Analytical and Bioanalytical Chemistry describes a project-based lab in which students investigate the distribution of Pb and As (from pesticides) in a contaminated apple orchard. Students have complete control of the lab, from designing a sampling strategy to using the primary literature to develop procedures for extracting the analytes and for their subsequent analysis by ICP-AES or ICP-MS. Currently 5.00/5 1 2 3 4 5 Rating: 5.0/5 (1 vote cast) Concepts, Instrumentation and Techniques in Atomic Absorption Spectrophotometry   by Richard D. Beaty and Jack D. Kerber Details This pdf file contains a well written and thorough introduction to atomic absorption suitable for use by undergraduates and faculty teaching instrumental analysis courses. Topics covered in the document include theoretical concepts and definitions, flame atomic absorption, instrumentation, analytical interferences, sampling techniques, graphite furnace atomic absorption, and plasma techniques. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Fluorescence Correlation Spectroscopy   by Petra Schwille and Elke Haustein Details Previously published as part of an online biophysics textbook, the article has rich and fairly complete scientific content. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) A Biosensor for Fullerenes and Carbon Nanotubes   by A. N. Kirschner, B. F. Erlanqer, S. R. Wilson Details This site contains an article that describes the use of surface plasmon resonance (SPR) spectroscopy to monitor real-time protein binding with fullerenes and carbon nanotubes. The introductory section provides a brief description of SPR and how it works. It next talks about the features of the Texas Instrument's SPR, known as Speetra, which is a small self-contained apparatus for light measurements. It is followed by sections discussing the properties of fullerenes and carbon nanotubes, and the methods of surface binding with monoclonal antibodies. Experimental procedures are discussed followed by example results. An analysis and explanation of results in the concluding discussion section provides useful guidance to students and practitioners. Currently 5.00/5 1 2 3 4 5 Rating: 5.0/5 (1 vote cast) Optics Tutorial   by Jeremy Learner and A. Thevenon Details This site provides a tutorial on electromagnetic waves using animated graphics. The tutorial gives the student the ability to visualize circularly polarized waves, the superposition of various types of polarized waves, and the change that results when the EM waves interact with matter. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Atomic Structure and the Periodic Chart   by Stephan Lower. Simon Fraser University Details Online eText gives a thorough descriptive overview of atomic structure. The site is organized into sections on light particles and waves, the Bohr atom, the quantum atom, atomic electron configuration, and periodic properties. Hyperlinks to interactive demonstrations of physiochemical principals with questions posed are included. At the end of each section, flowcharts, called "concept maps" guide the students from basic principles to working concepts. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Animated Vibrational Modes of Triatomic Molecules   by American Chemical Society Details Molecular vibration modes are discussed using animation to depict atomic motion. As examples, the fundamental vibrational modes and their composite superposition are demonstrated for sulfur dioxide and carbon dioxide. A brief overview of the approach for calculating molecular vibrational modes is included with references to basic literature on the topic. Atomic motion resulting from the superposition of fundamental modes is discussed in relation to effects of molecular vibrations on reactivity. The site is a Journal of Chemical Education Online article. QuickTime is required to view the animations. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Fourier Transform   by Brian M. Tissue Details An overview of the Fourier theorem as applied to analytical measurements is given. The Discrete Fourier Transform and the Fast Fourier Transform algorithms are mentioned, and sampling requirements are discussed. Links are provided to descriptions of Fourier transform based mass spectrometry, infrared spectroscopy and NMR techniques. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Handbook of Basic Atomic Spectroscopic Data   by J.E. Sansonetti and W. C. Martin Details This National Institute of Standards and Technology (NIST)) site containing atomic spectroscopic reference data. Information can be accessed through a variety of means, such as an interactive periodic table and dropdown lists of elements organized by name or atomic number. Data available include isotope abundance, electron configuration, nuclear spin, magnetic moment, ionization energies, spectral line wavelengths and intensities, and energy level information. References are also given. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) UV-visible spectroscopy   by Jim Clark Details This webpage, part of a larger project "Understanding Chemistry", provides a solid introduction to UV-vis spectroscopy suitable for use in introductory chemistry and introductory analytical chemistry courses. The UV-vis pages discuss UV-vis light, absorption, Beer's law, the double-beam spectrometer, and introduce some standard applications of UV-vis spectroscopy. Explication is clear and thoughtful. Judicious and effective use of graphics. Site is easy to navigate, and the links work. Some typos. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Reliable Measurements: A Guidebook for Trace Analysts   by Dr. Paul Gaines Details Provides a comprehensive resource on sample preparation and analysis for those interested in elemental determinations by atomic spectrometry, especially ICP-OES and ICP-MS. Issue such as sources of contamination, detection limits, sample preparation, standard stability, and method validation are well covered. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) HPLC, LC-MS, and FTIR sites   by Shula Levin Details This site contains a considerable amount of information on HPLC, LC-MS, and FTIR via linked sites by the same author and some vendor sites. It may require considerbale time to follow the links to find specific information, but as a collection of sites related to HPLC and FTIR it is quite useful as a teaching resource. There are some interesting animations that might be helpful for students to understand how these instruments work. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Chemistry-Based QuickTime Movies, Animations, and Streaming Audio   by Chasteen, Thomas G. Details Downloadable animations and movies for analytical instruments and processes. Formats in QuickTime, GIF animations, and Flash animations. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Analytical Instruments and Spectroscopic Concepts   by Chasteen, Thomas G. Details Primers for different analytical techniques (HTML, PDF). Also links to animations and audio descriptions of analytically related concepts. Techniques include atomic absorption, spectrophotometry, chemiluminescence, gas chromatography, mass spectrometry, and atomic emission. Currently 1.00/5 1 2 3 4 5 Rating: 1.0/5 (1 vote cast) FTIR Spectrometry   by Paul L. Edmiston Details The site demonstrates principles behind the operation of the interferometer in an FTIR spectrometer. Graphics and interactive movies are used. Examples start from a single wavelength and build to the superposition of multiple wavelengths. The connection between an interferogram and a frequency domain spectrum is discussed. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Experimental and Teaching Modules   by EAMNET Details The site contains a set of experimental and teaching modules that cover the fundamentals, history and practice of microscopy. Modules on microscopy, FRET, FRAP and Quantitative Multidimensional Microscopy will be of interest to chemists and biologists. Several include great graphics that would be helpful additions for instrumental analysis lectures. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Terahertz radiation: applications and sources   by Eric R. Mueller Details The site describes applications and basic instrumentation for terahertz spectroscopy. It contains an article that originally appeared in the American Institute of Physics publication The Industrial Physicist. Sources for terahertz spectroscopy and imaging applications are emphasized. A bibliography with suggestions for further reading is included. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) ICP Operations: A Guide for New ICP Users   by Dr. Paul Gaines Details A handbook for ICP analysis. Topics such as matrix compatibility, quality control, spectral interferences, instrument operation (e.g. sample introduction, nebulization, etc.) make this an excellent practical yet concise manual on ICP operation. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) SPECTROPHOTOMETRIC DETERMINATION OF ASCORBIC ACID IN ...   by M. Umar Dahot et al. Details An article that describes the flow injection analysis determination of ascobic acid using iron phenanthroline as a redox reagent and UV vis detection. Currently 4.00/5 1 2 3 4 5 Rating: 4.0/5 (1 vote cast) SPR : Surface Plasmon Resonance Tutorial   by Arnoud Marquart Details Provides a straightforward introduction to the fundamentals of SPR, the genesis of the plasmon and the evanescent wave, and how SPR can be used to monitor the chemical nature of species adsorbed to the surface of a metal substrate. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Encylcopedia of Laser Physics and Technology   by Rudiger Paschotta Details This is a comprehensive encyclopedia that provides a brief definition or explanation of a keyword term or principle of laser physics and technology. The site is organized so that one can click on an alphabet letter to get a listing of keywords or terms for searching. This site will be useful for novices in the field and anyone who needs a refresher or reminder of terms and definitions. Most useful to upper division undergrads, graduate students and practitioners who need to learn terms to navigate the field of laser optics. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Spectroscopy   Details This site describes the theory and practice of IR and NMR spectroscopy for classroom and laboratory instruction. Although it is written for a course at the University of Colorado, Boulder, this site is appropriate for anyone doing analytical measurements with infrared or NMR. Currently 3.00/5 1 2 3 4 5 Rating: 3.0/5 (1 vote cast) Laser-induced Remote Sensing for Chemistry and Micro-imaging   by Los Alamos National Laboratory Details Discusses remote sensing instrumentation utilized for rapid characterization of rocks and soils on planetary surfaces in support of explorations on Mars. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Organic Chemistry On Line   by William Reusch Details This site covers introductory material related to the analysis of small organic molecules by mass spectrometry, UV-visible, IR, and NMR spectroscopy. A concise explanation of each approach is presented with illustrations. This would be useful for those teaching organic chemistry and for others who need a review of the topic. The section on Spectroscopy Resources at the end of the site contains a list of links to additional information plus a several links to compilations of problems (and their solutions) that challenge the student to interpret NMR or IR spectra. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) SPR and Related Calculations   by Rob Corn Details Computation of Surface Plasmon Resonance using common surfaces (gold, silver, copper) and wavelengths (632.8 nm) is done on-line. The site is maintained for researchers and students alike. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Coal Sampling   by D. W. Golightly and F. O. Simon Details This USGS method explains the use of fluxes for preparation of coal for elemental analysis. Useful to supplement textbooks concerning sample preparation and may be useful in designing an XRF laboratory experiment. Currently 3.00/5 1 2 3 4 5 Rating: 3.0/5 (1 vote cast) Compilation of FTIR Materials   by Michael C. Martin Details Provides excellent tutorials on the principles of IR absorption, interpretation of spectra for structure determination, a spectral peak wizard, an authoritative glossary of spectroscopic terms, and links tutorials on how FT instruments work. Currently 0.00/5 1 2 3 4 5 Rating: 0.0/5 (0 votes cast) Fluorescence Detection Anim