Techniques Applications Learning Resources Teaching Resources JASDL
computations
electrochemistry
immunoassay
instrumentation
mass spectrometry
NMR
separations
spectroscopy
surface methods
application library
bioanalytical
databases
environmental
forensic
materials
nano methods
quantitative analysis
animations
Etexts
exercises
laboratory experiments
lecture materials
tutorials
videos
virtual labs
active learning
assessments
best practices
Courseware
Labware
Educational Practices
Undergraduate Research




Your search results for Class Material returned 217 results.

Analytical Electrochemistry: A Laboratory Manual Details
Description: This labware module contains directions for seven experiments in analytical electrochemistry. The experiments are designed to illustrate fundamentals of electrode reactions as applied to readily accessible redox reactants. They provide insight to dynamic electrochemistry for scientists at all levels of training. Activation procedures to prepare glassy carbon electrodes are provided in a TechNote.

2D NMR Spectroscopy Details
Description: This site provides a concise, but thorough introduction to NMR spectroscopy with a focus on 2D NMR. This site will be most useful for students with some introductory background in NMR. The basic principles of common 2D NMR experiments are presented and illustrated with spectra. Instructors wanting to illustrate the appearance of a TOCSY, NOESY, or COSY spectrum to an undergraduate class will also find useful information on this web site.

A Beginners Guide to Ion-Selective Electrode Measurements Details
Description: A relatively comprehensive presentation of the theory, types, practices, and errors associated with ion selective electrodes. Information is listed in a hyperlinked table of contents. The last section of the site includes a thorough glossary of terms.

A Biosensor for Fullerenes and Carbon Nanotubes Details
Description: This site contains an article that describes the use of surface plasmon resonance (SPR) spectroscopy to monitor real-time protein binding with fullerenes and carbon nanotubes. The introductory section provides a brief description of SPR and how it works. It next talks about the features of the Texas Instrument's SPR, known as Speetra, which is a small self-contained apparatus for light measurements. It is followed by sections discussing the properties of fullerenes and carbon nanotubes, and the methods of surface binding with monoclonal antibodies. Experimental procedures are discussed followed by example results. An analysis and explanation of results in the concluding discussion section provides useful guidance to students and practitioners.

A Dip in the Dribble Details
Description: This site is exactly the kind of material that is useful in a digital library like ASDL. The site provides detailed information on a problem-based learning analytical environmental case study centered around an industrial accident in the college classroom providing detailed information for interested instructors on how to use it and do it well - questions to ask, and answers to these questions. The case asks students to investigate methods for analyzing the pollutant, to develop a sampling plan, solicit bids from contractors for the necessary analytical work and to finalize the monitoring program. This companion link provides the materials given to the students in the classroom.

A Pictorial Representation of Product Operator Formalism: Non-Classical Vector Diagrams for Multidimensional NMR Details
Description: This site presents a pictorial description of the product operator formalism using a non-classical vector approach. This approach allows for the representation of any arbitrary multidimensional or heteronuclear NMR experiment. A description of a complete set of 16 vector representations for weakly-coupled two-spin (I=1/2) systems is given followed by an extension of this set to three-spin systems. Finally the concepts of coherence transfer, multiple quantum spectroscopy and phase cycling are illustrated using 2D COSY, 2D INADEQUATE, DEPT and sensitivity-enhanced HSQC as examples. The content is geared to those that have some background in NMR spectroscopy, and is probably most appropriate for a graduate course in NMR. As this non-classical vector representation is used to pictorially depict product operators a basic understanding of product operators would serve the reader well. The text is well written and referenced. The figures being the heart of the manuscript are very well done and easy to follow with concise figure captions. The examples are well chosen and show how easily sequences can be described with this approach. In the case of the sensitivity-enhanced HSQC it is particularly effective in showing how the unobservable magnetization at the end of a normal HSQC is converted to observable magnetization by the additional pulses and thus generating the enhancement. This site can be used as a teaching tool as well as by practitioners who would like to easily deconstruct a pulse sequence for a better understanding of the “spin engineering” involved.

Accelerator Mass Spectrometry in Biology and Health Care Details
Description: This video, developed at Lawrence Livermore National Laboratory, describes the instrumentation for accelerator mass spectrometry and its applications. The video describes the instrumentation and its application for carbon dating and measurements of drug distribution.

Acid/Base Equilibria Details
Description: A number of examples of mathematical treatment of strong and weak monoprotic acids and bases, as well as buffers. The site presents a brief conceptual introduction to each case and then treats mathematically the steps to solve an example problem related to the concept.

Adsorption and Chromatography in Bioseparations Details
Description: This material was developed for a final year undergraduate bioseparations module. There are a number of links to sites for modeling adsorption chromatography. For example, a link to an Excel spreadsheet provides a demonstration of varying N, l, and K (or alpha)affect band separation. Other links explain adsorption isotherms in the context of bioseparations.

Advanced Chemistry Development Details
Description: This site contains slides to accompany lectures in HPLC. They do not contain enough description for the average student to follow. However, they provide a lot of excellent information about practical aspects of HPLC that faculty could find useful for their own lectures on the topic. The sections on troubleshooting, sample preparation, gradients, system peaks, system suitability and methods validation are particularily valuable. The illustrations and diagrams are informative but occasionally difficult to read because of their resolution. Applications and examples are very good. This is a subset of Dr. Levin's more extensive page regarding chromatography, but a link to that home page is provided.

Affinity Chromatography Details
Description: This is an experiment showing the application of affinity chromatography to the separation of albumin from horse serum. A brief introduction of affinity chromatography and how it is being used in this specific experiment is given. This appears to be a good experiment to show the advantages of affinity chromatography in separating specific proteins from a complex matrix and would be useful in a biochemistry course or a course that is specifically looking at differing types of chromatography.

Affinity Chromatography Details
Description: Using exposition, graphics, and commercial videos, this module teaches the theory and application of affinity chromatography in the characterization of proteins, nucleic acids, and other biochemical/biomedical systems. Problems and application examples support the tutorial material.

All about light -- diffraction, reflection, gratings, animations Details
Description: This is a very detailed site about the physics of electromagnetic waves including diffraction and interference. The site has several components. A large list of animations is provided, but several of the links are no longer active, so this feature is less useful than it could be. The site also has a series of lecture notes, as pdfs, and nice slides that describe various aspects of the behavior of electromagnetic radiation. This site may be useful for instructors teaching spectroscopy. Students may need some advice about where to go and what to do.

An Introduction to Surface Chemistry Details
Description: Theoretical and descriptive material for an introductory surface science course. Topics covered include structure of surfaces and detailed information on a variety of surface analytical techniques, essentially an online text.

An Unusual Arson Case: Polymer Grains Details
Description: A case example of determination of an arson accelerant by a variety of analytical techniques. Will make a good case record for an active learning class. Uses a variety of techniques, particularly chromatography and headspace analysis.

Analytical Chemistry Details
Description: Lecture notes for 1st semester are on titrations, gravimetry, kinetics and electrochemistry (redox). Potentiometry, coulometry, voltammetry, spectroscopic and separation methods are presented during 2nd semester, illustrated with QuickTime animations.

Analytical Chemistry Details
Description: This site contains a list of detailed lecture notes covering a wide range of topics including equilibrium, titrations, sample preparation, acids and bases, buffers, spectrophotometry, potentiometry and chromatography. This site is part of a collection of notes from a general chemistry course taught at the State University of West Georgia. This well-linked page gives supplementary material that could be useful to intermediate chemistry majors in an analytical chemistry course or new faculty developing a course.

analytical chemistry lab manual Details
Description: This is a lab manual for an undergraduate analytical laboratory course. Experiments include fairly typical exercises such as acid/base titration, EDTA titrations, liquid chromatography analysis of chocolate (caffeine, theobromine, vanillin), vanillin by spectrophotometry (solvent extraction + solid phase extraction), ion selective electrodes, and GC of fatty acids via derivitization. Note that some of the supplementary materials referred to in the manual are posted in Blackboard and are unavailable to the public.

Analytical Electrochemistry: Basic concepts Details
Description: This module focuses on dynamic electrochemistry, that is, the combination of mass transfer and electrochemical reaction typical of redox reactions at the interface between solids and fluids when current is not zero. It is an introduction at a level appropriate for undergraduates in their sophomore or junior years.

Analytical Electrochemistry: Potentiometry Details
Description: This courseware module is structured for either a lecture presentation or self-study tutorial on analytical potentiometry. The level of presentation spans upper high school to college students. Topics include historical background, theory/principles, instrumentation, pH electrodes, experimental examples, and troubleshooting tips.

Analytical Instruments and Spectroscopic Concepts Details
Description: Primers for different analytical techniques (HTML, PDF). Also links to animations and audio descriptions of analytically related concepts. Techniques include atomic absorption, spectrophotometry, chemiluminescence, gas chromatography, mass spectrometry, and atomic emission.

Analyzing Ligand-Protein Binding Details
Description: This website consists of a text file that describes the analysis of radioligand binding experiments in a step-wise, easy to follow sequence. Although this site will be most useful to students trying to understand radioligand binding, the discussion is applicable to other types of ligand-protein binding experiments. The site also discusses the limitations of Scatchard plots for data analysis and the importance of nonlinear fitting of binding data.

Animated Vibrational Modes of Triatomic Molecules Details
Description: Molecular vibrational modes are discussed using animation to depict atomic motion. As examples, the fundamental vibrational modes and their composite superposition are demonstrated for sulfur dioxide and carbon dioxide. A brief overview of the approach for calculating molecular vibrational modes is included with references to basic literature on the topic. Atomic motion resulting from the superposition of fundamental modes is discussed in relation to effects of molecular vibrations on reactivity. The site is a Journal of Chemical Education Online article. QuickTime is required to view the animations.

Animated Webpage Explaining STM Details
Description: This is an animated gif that illustrates how scanning tunneling microscopy (STM) works. As such it is valuable to students and faculty interested in learning about this important surface analysis technique.

Animation of diode array detection in HPLC Details
Description: This site is one in a series of sites with very good animations related to separations. This animation deals specifically with diode array detection for liquid chromatography. The animations are short (one to two minutes) and can easily be shown in class as part of a lecture. They are extremely helpful in illustrating key components and concepts of chromatographic systems. Users are encouraged to explore the site and the other brief animations as well. Separate links to other simulations by the same company (TRSL) are also listed on ASDL. This site requires FLASH version 7 or higher in order to work properly

Animation of Dual Head HPLC Pump Details
Description: This site is one in a series of sites with very good animations related to separations. This animation deals specifically with dual head LC pumping. The animations are short (one to two minutes) and can easily be shown in class as part of a lecture. They are extremely helpful in illustrating key components and concepts of chromatographic systems. Users are encouraged to explore the site and the other brief animations as well. Separate links to other simulations by the same company (TRSL) are listed below.

Animation of GC flame ionization detector Details
Description: This site is one in a series of sites with very good animations related to separations. This animation deals specifically with flame ionization detection in GC. The animations are short (one to two minutes) and can easily be shown in class as part of a lecture. They are extremely helpful in illustrating key components and concepts of chromatographic systems. Users are encouraged to explore the site and the other brief animations as well. Separate links to other simulations by the same company (TRSL) are also listed on ASDL.

Animation of GC solvent focusing Details
Description: This site is one in a series of sites with very good animations related to separations. This animation deals specifically with solvent focusing in gas chromatography. The animations are short (one to two minutes) and can easily be shown in class as part of a lecture. They are extremely helpful in illustrating key components and concepts of chromatographic systems. Users are encouraged to explore the site and the other brief animations as well. Separate links to other simulations by the same company (TRSL) are listed below.

Animation of pulse dampner in HPLC Details
Description: This site is one in a series of sites with very good animations related to separations. This animation deals specifically with pulse dampners is LC and could help in a general lecture about LC pumps. The animations are short (one to two minutes) and can easily be shown in class as part of a lecture. They are extremely helpful in illustrating key components and concepts of chromatographic systems. Users are encouraged to explore the site and the other brief animations as well. Separate links to other simulations by the same company (TRSL) are also listed on ASDL.

Animation of Quadrupole GC-MS detection Details
Description: This site is one in a series of sites with very good animations related to separations. This animation deals specifically with quadrupole mass spectrometry detection for chromatography. The animations are short (one to two minutes) and can easily be shown in class as part of a lecture. They are extremely helpful in illustrating key components and concepts of chromatographic systems. Users are encouraged to explore the site and the other brief animations as well. Separate links to other simulations by the same company (TRSL) are listed below.

Animation of sample loop HPLC injections Details
Description: This site is one in a series of sites with very good animations related to separations. This animation deals specifically with sample loop injections in liquid chromatography. The animations are short (one to two minutes) and can easily be shown in class as part of a lecture. They are extremely helpful in illustrating key components and concepts of chromatographic systems. Users are encouraged to explore the site and the other brief animations as well. Separate links to other simulations by the same company (TRSL) are listed below.

Animation of Single Head Check Valve HPLC Pump Details
Description: This site is one in a series of sites with very good animations related to separations. This animation deals specifically with reciprocating pumps for liquid chromatography. The animations are short (one to two minutes) and can easily be shown in class as part of a lecture. They are extremely helpful in illustrating key components and concepts of chromatographic systems. Users are encouraged to explore the site and the other brief animations as well. Separate links to other simulations by the same company (TRSL) are listed below.

Animation of single wavelength UV-vis detection for HPLC Details
Description: This site is one in a series of sites with very good animations related to separations. This animation deals specifically with single wavelength UV-vis detection for liquid chromatography. The animations are short (one to two minutes) and can easily be shown in class as part of a lecture. They are extremely helpful in illustrating key components and concepts of chromatographic systems. Users are encouraged to explore the site and the other brief animations as well. Separate links to other simulations by the same company (TRSL) are also listed on ASDL.

Animations and Simulations in the Teaching of Analytical Sciences Details
Description: This article by Cynthia Larive, published in the "ABCs of Teaching Analytical Science" series of the journal Analytical and Bioanalytical Chemistry, will be of interest to faculty members teaching courses in the analytical sciences. The article provides a good introduction to the animations, simulations, and other on-line resources available on the internet. More important, it encourages instructors to develop a teaching philosophy that emphasizes the use of these materials.

Animations in an Instrumental Methods Chemistry Class? Details
Description: This website provides an introduction to animations as a tool for teaching instrumental techniques in the instrumental analysis course - why one might wish to use animations, some information on how to go about developing them, and it provides a number of examples of animations for analytical instrumentation. One problem with the site is that some of the animations emphasize instrumentation that is not frequently used today. For example, the section on ICP shows an instrument with the classical Rowland Circle configuration and the section on GC-MS shows an animation of a sector mass spectrometer. Nonetheless, the site should prove a valuable resource to college educators teaching analytical chemistry.

Anodic Stripping Voltammetry Details
Description: Site provides basics with illustrations of what happens during deposition and stripping of metals for analysis by anodic stripping voltammetry (ASV). The PDF presentation is easy to navigate and understand. It can be used as a supplement to a lecture or lab.

Applications Searchable Site Details
Description: This site is a search engine for chromatographic and mass spectral methods in the Waters Corporation database. It searches based on analyte. It pulls up refereed journals(citations only) and company literature (pdf format). The site claims 23,500 documents. The site will be useful to those looking for methods in chromatography, including faculty and students looking for project ideas for either research or laboratory experiments.

Atomic Absorption Instruction Module Details
Description: An introduction to Atomic Absorption Spectroscopy for the non-chemist or new user.

Atomic Emission Spectroscopy Details
Description: Directed to students in Instrumental Analysis or practitioners without convenient access to a class in Instrumental Analysis, this module explains the instrumental systems and interactions involved in atomic emission for elemental analysis. Completion of the module will leave the learner with knowledge of optics, plasma sources, and trade-offs in choosing the right instrument for a given analytical task.

Atomic Spectroscopy in a Project-Based Lab Details
Description: This article by Dulasiri Amarasiwiwardena, published in the "ABCs of Teaching Analytical Science" series of the journal Analytical and Bioanalytical Chemistry, will be of interest to faculty members teaching course in analytical chemistry or environmental chemistry. The paper describes a project-based lab in which students investigate the distribution of Pb and As (from pesticides) in a contaminated apple orchard. Students have complete control of the lab, from designing a sampling strategy to using the primary literature to develop procedures for extracting the analytes and for their subsequent analysis by ICP-AES or ICP-MS. Although the project itself may not be transportable, the project's methodology can be adapted to other environmental projects.

Atomic Structure and the Periodic Chart Details
Description: This online eText consists of a thorough descriptive overview of atomic structure. The presentation is at a level suitable for high school or general chemistry students at the college level. However, the historical context of understanding atomic stucture and covderage of essential experiments and theoretical developments make this site suitable as a review primer for upper level undergraduates. The site is well organized and separated chronologically into section on quantum; light particles and waves; the Bohr atom; the quantum atom; atomic electron configuration (Aufbau); and periodic properties. It contains hyperlinks to interactive demonstration of physiochemical principals with questions posed. At the end of each section, flowcharts, called "concept maps" guide the students from basic principles to working concepts.

Basic Liquid Chromatography Details
Description: A complete textbook of liquid chromatography by Yuri Kazakevich and Harold McNair on the Web. Extraordinarily comprehensive in its coverage of fundamental chromatographic theory and instrumentation for a website.

Biological Animation Library Details
Description: This site produced by the Dolan DNA Learning Center of the Cold Springs Harbor Laboratory contains a number of high quality animations that explain processes important in bioanalytical chemistry. For example, one animation illustrates the process of Sanger sequencing and another explains what Gene Chips are and how they work. PCR, gel electrophoresis, cloning, model organisms and stem cell lines are also treated. The site allows the animations to be viewed or downloaded for PC or Mac, which means that they can be easily incorporated into lectures.

Busy Researchers Guide to Chromatography Details
Description: The Busy Researchers' Guide to Chromatography is a pdf book focused on the vendor's (PerSeptive Biosystems) products (perfusion-based chromatography) with an eye toward their application in bioanalysis. The book is a nicely written and practical introduction to chromatography suitable for use with undergraduates. The last several chapters define the basics of liquid chromatographic separations and the first few give a nice overview of how one does a method development for a specific biological separation.

Capillary electrophoresis movie Details
Description: This website is an animation describing aspects of CE separations, including electroosmotic flow, the separation, injection (hydrodynamic and electrophoretic) and detection (direct and indirect).

Capillary Electrophoresis Primer Details
Description: This site presents a primer on capillary electrophoresis. This is a very complete treatment covering the basic theory of CE, sample stacking techniques, and practical information about optimizing CE separations. There is an animation showing how to properly cut a capillary and a glossary of terms for analytical validation. The site provides theory and background to CE but perhaps not as in as much depth as an introductory instrumentation text. On the other hand it has a large range of practical tips that a student would not necessarily get from a text. The link to "Helpful Hints for Improved Capillary Electrophoresis" which includes a section on selection of buffers, tables of buffer pKa's, buffer additives, conditioning capillaries and troubleshooting problems.

CASE TEACHING NOTES for Filthy Lucre Details
Description: The website presents a case study involving the detection of cocaine on dollar bills. The case study uses GC-MS, but has an introduction appropriate for beginning chemistry students.

Cell Phone Spectrophotometer Details
Description: Instructions and software are provided to allow students to build an inexpensive spectrophotometer, using digital cameras or cell phone cameras as array detectors. Supplementary materials include instructions for high school teachers and laboratory instructions for both high school and college students. Software source code allows customization.

Chem 212 - Separations Science Details
Description: Superb website providing instructional materials in support of a problem-based learning approach to Quantitative Analysis (equilibria and separations). Materials available include textbook chapters, in-class, and out-of-class problems, a peer/peer evaluation tool, and a handout in support of a final course lab project report. The majority of materials are provided in an Adobe pdf format - very helpful for adoption by interested faculties.

CHEM 525 NMR Spectroscopy Details
Description: This site provides both classical and quantum mechanical descriptions of NMR. Some nuts and bolts aspects of NMR and the basics of two-dimensional spectroscopy are also covered. This web site should be informative for graduate students or professionals seeking a more thorough understanding of the basic principles underlying NMR spectroscopy.

Chemical Equilibria: The Law of Mass Action Details
Description: Fundamental ideas and terminology of equilibria from a general chemistry perspective. A focus on closed systems, reversible chemical reactions, the law of mass action, Q and K. Also included are several multiple-choice questions that test the theories discussed. This site provides supplementary material that could be useful to beginning students in general and analytical chemistry.

Chemical Equilibrium in the Gas Phase Details
Description: This website describes gas phase equilibrium chemistry and provides a tutorial on key concepts like LeChatelier's principal and includes on-line exercises in which the reader can check their understanding. Calculations of equilibrium constants expressed in terms of pressure and concentration are presented. This site will be most useful for high school and introductory university Chemistry courses in which students are developing an understanding of equilibrium chemistry.

Chemical Separations Details
Description: This site contains complete notes in a PowerPoint-like presentation for a chemical separations course. It covers a wide variety of topics, including distillation, extraction, gas chromatography, liquid chromatograpy, chromatography theory, instrumentation, electrophoresis, field flow fractionation, and affinity chromatography. It covers these topics thoroughly using a clear, consistent, and simple presentation style. Links to major topics like GC, LC, and electrophoresis provide specific information about the theory, instrumentation, and practice related to these techniques. Many students will find this, and its companion sites, quite helpful.

Chemistry 160: Physical Measurements and Analysis Details
Description: Site contains lab experiments for both analytical and physical chemical measurements. There are 6 analytical experiments: data acquisition, AAS, voltammetry, ASV, GC-MS, stop-flow kinetics and HPLC. Experiments use real samples and are ready for implementation.

Chemistry Experiment Simulation, Tutorials and Computer Animations for College Chemistry Details
Description: After instructions on what computer programs will be needed, you can simulate chemical processes related to electrochemistry, acid-base chemistry, stoichiometry and kinetics.

Chemistry: WebElements - The Periodic Table on the WWW Details
Description: This site, WebElements, is a sourced of information on all the elements of the periodic chart. Clicking "on" an element in the periodic chart brings basic information of the element, like atomic number and weight, and a picture of what the element appears visually. If you go to the "scholar edition" additional information about the elements is provided such as physical and chemical properties including bond energies, electron affinities, radii, electronic configuration, nuclear, crystallographic, etc. It serves as a ready source of basic information about the elements from element #1 to #102. Browsing through the website is simple and direct. It also has the elemental name in other languages beside English for global use. Convenient site for a wide range of users.

Chrom. and Electrophoresis experiments with PDFs Details
Description: A site with PDF links to several slab gel electrophoresis, HPLC, and GC experiments intended for high school or college audiences. This site may provide a useful starting point for faculty seeking to implement new laboratory experiments based on these techniques. A login (email address) is required, but once logged in, follow the "Free Resources" link to see many instrumental and analytical experiments that have been submitted to the site.

Chromatography Details
Description: An introductory site about chromatography that does not go into great depth. However, the simulation of paper chromatography is worth exploring with students as it illustrates that the separation of compounds relies on the difference in the solutes affinities for the mobile phase relative to the stationary phase. Because of its apparent simplicity, this simulation has significant pedagogical potential and could be used in a variety of ways in class to explore the factors governing chromatographic separations.

Chromatography Details
Description: Multiple links in a broad discussion of several facets of chromatography - including theoretical and instrumental aspects. Five modes of chromatography are highlighted: GC, HPLC, LC, SEC and TLC.

Chromatography Details
Description: This site provides fundamental background information about chromatogaphy, including plate theory, rate theory, the meachanisms of separations, and qualitative and quantitative aspects of chromatography. The format is a PowerPoint-like presentation. It is a subsite of a larger, broader site about chemical separations (http://ull.chemistry.uakron.edu/chemsep/index.html). The combination of all of the related sites is quite nice and students will find them useful.

Chromatography and Mass Spec Lectures Details
Description: This site contains mass spectrometry and chromatography lecture notes for a graduate course. They are subdivided by topic (history, theory, etc.) and are easy to browse. They may be helpful to someone constructing their own course in chromatography and/or mass spectrometry. The notes are fairly complete. The historical sections may particularly save time in preparing courses. The notes also provide good information and a helpful outline to follow. The site also has some nice mass spectrometry animations from Thermo.

Chromatography books Details
Description: This site simply offers books covering a wide range of both general and specific topics related to gas chromatography and its applications. While not of immediate pedagogical value, it may be useful to those looking for good texts about gas chromatography either for their own research needs or to provide as resources to their students.

Chromatography Nomenclature and Definitions Details
Description: This website gives the IUPAC approved definitions in the field of chromatography. It is critical for students to appreciate the importance of using standardized nomenclature and definitions.

Chromatography Theory Details
Description: This site contains standard definitions related to chromatgraphy similar to treatments found in analytical textbooks. It introduces the beginning student to LC concepts relevant to biochemistry and includes a good example of choosing a mobile phase pH for a protein separation based on ion exchange.

Chromatography Theory Details
Description: James Hardy has produced a number of powerpoint type lecture modules for analytical chemistry. This is another very good module that covers the introductory theory of chromatography. Includes chromatography types, plate and kinetic theories. Level of presentation is at the introductory analytical chemistry level. It is a colorful and well planned presentation of the introduction to chromatography that could be used as the basis for lectures on chromatography at the introductory analytical chemistry or instrumental analysis level.

Chromatography theory and modes Details
Description: This site is an introductory lecture in outline form about chromatography. It appears directed toward biochemical separations. The coverage is broad but not deep. Discussions of counter-current separations, gel permeation, and ion exchange are accompanied by some mention of partition, paper, and gas chromatography

Coal Sampling Details
Description: This USGS method explains the use of fluxes for preparation of coal for elemental analysis. Useful to supplement textbooks concerning sample preparation and may be useful in designing an XRF laboratory experiment.

Compilation of FTIR Materials Details
Description: This site has a group of excellent tutorials on the principles of IR absorption, interpretation of spectra for structure determination, a spectral peak wizard, an authoritative glossary of spectroscopic terms, and links tutorials on how FT instruments work.

Concepts, Instrumentation and Techniques in Atomic Absorption Spectrophotometry Details
Description: This pdf file contains a well written and thorough introduction to atomic absorption suitable for use by undergraduates and faculty teaching instrumental analysis courses. Topics covered in the document include theoretical concepts and definitions, flame atomic absorption, instrumentation, analytical interferences, sampling techniques, graphite furnace atomic absorption, and plasma techniques.

Craig countercurrent extraction machine applet Details
Description: This site provides a useful applet that demonstrates countercurrent extraction. The explanation of the method is short, but good. The level is appropriate for undergraduate students. The Applet itself is well designed and provides a useful exercise for students around which homework or small-group waork could be developed. The use of color is particularly helpful. The same author has a larger collection of applets about instrumentation and other analytical concepts in the ASDL collection. It can be found by searching the ASDL library using 'applets' as the keypword, or going to the site: http://www.chem.uoa.gr/applets/Applet_Index2.htm

Custom Designed HPLC Couse for Teva Abic Details
Description: This site contains slides to accompany lectures in HPLC. They do not contain enough description for the average student to follow. However, they provide a lot of excellent information about practical aspects of HPLC. The sections on troubleshooting, sample preparation, gradients, system peaks, system suitability and methods validation are particularily valuable. The illustrations and diagrams are informative but occasionally difficult to read because of their resolution. Applications and examples are very good. This site is a subset of Dr. Levin's larger site related to teaching separations and other analytical topics, but a link to her home page is provided.

Cyclic Voltammetry Details
Description: This site describes a cyclic voltammetry experiment at a Au electrode to determine the electrode capacitance (in the presence and absence of octadecane thiol), the formal potential and diffusion coefficient of ferricyanide, and the CV irreversibility with Co(NH3)6+3. A tutorial-like discussion of the above subjects is presented. Experimental procedure can be readily implemented in courses such as instrumental analysis

Cyclic Voltammetry Details
Description: This site provides an excellent experiment involving cyclic voltammetry at a gold electrode. The experiment includes a detailed introduction to the topics of electrode capacitance, electrode reactions, and flux of the electroactive species to electrode surface. Lab report guidelines and post-lab questions are included.

Cyclic Voltammetry Simulator Details
Description: This simulator allows the modeling of responses from experiments in cyclic voltammetry, and is applicable to a wide variety of parameters. Excellent instructional aids in text form include description of electrochemical reversibility, diffusion, instrumentation and interpretation of cyclic voltammograms, with real-time demonstration of parameter changes.

Determination of DNA Bases Chemistry: A Discovery-Based Experiment Details
Description: The paper contains details of an electrochemistry lab where students are given the time to explore and design an experiment to identify the different DNA bases. The paper has a very useful compendium of literature relating to electrochemical techniques.

DNA Amplification for Forensic Analysts Details
Description: This web site describes the ampification polymerase chain reaction (PCR)process typically employed for the forensic analysis of DNA. Emphasis is placed on the selection of core short tandem repeat(STR)and Y-STR loci for conducting PCR. The concept of multiplexing is reviewed.The site is designed as an on-line short course with excellent graphic support. The user must register and secure a readily obtainable password prior to entering the site

DNA Evidence Training Details
Description: These training modules are intended to provide interactive training that covers basic information about the identification, preservation, and collection of DNA evidence at virtual crime scenes related homicide, sexual assault, and burglary. Information addressed in this interactive training program is delivered in two modules. The Beginning Level Module focuses on issues that arise for the first-responding law enforcement officer. The Advanced Level Module delivers more in-depth information for the evidence technician. Also included are test questions, a glossary, and references.

DNA Extraction and Quantitation for Forensic Analysts Details
Description: This web site is part of the President's DNA Initiative and is devoted to the methodology for the extraction and quantification of DNA obtained from crime scene evidence. The site is designed as an on-line short course. The site identifies potential obstacles in the collection, extraction, and amplification of DNA. Extraction methods covered are organic, Chelex, and other extraction procedures. The site reviews inhibitors of the polymerase chain reaction (PCR) process and suggests methods for separating these inhibitors from the sample DNA. The advantages and disadvantages of commonly used quantitation methods for DNA are reviewed. The user must register and secure a readily obtainable password prior to entering the site.

Dual Beam Spectrometer Details
Description: The Quick Time movie describes the operation of a dual beam spectrometer using an optical wedge to improve the accuracy of the absorbance measurement. The Tunable Monochromator Movie is an excellent companion movie

Educator's Reference Guide for Electrochemistry Details
Description: This website contains a substantive discussion on the basics of voltammetry accompanied by description of cells, electrodes and example experiments from use of cyclic voltammetry and to comparison between chronoamperometry, chronopotentiometry and cyclic voltammetry. The discussion of the basics is not aimed for commercial purposes although the experiments do employ examples from use of Pine Instrument potentiostats.

Electrochemical Detection of Phenol Utilizing a Synthesized Sonogel-carbon Zirconium Oxide Details
Description: This experiment is designed for senior undergraduate students in an inorganic chemistry course. Students are asked to synthesize a sonogel-carbon electrode that is modified with a ZrO2 sol-gel and to compare the results to those of an unmodified electrode for the detection of phenol.

Electrochemical Education Details
Description: The purpose of this site is to collect in one location resources useful to educators attempting to incorporate modern electrochemical techniques into the undergraduate chemistry curriculum.” Contains links to material on experiments, equipment, proposal writing, etc.

Electrochemistry and Detection of Organic and Biological Molecules such as Catechols Details
Description: This ASDL online article describes a lab experiment whereby students learn how to prepare a conducting thin-film polymer electrode for the analysis of catechol and the effect of ascorbic acid on the cyclic voltammetric results.

Electromagnetic waves and circular dichroism:an animated tutorial Details
Description: This website provides a tutorial on electromagnetic waves using animated graphics. The tutorial gives the student the ability to visualize, plane, and circularly polarized waves, the superposition of various types of polarized waves, and the change that results when the EM waves interact with matter.

ELISA Animated Virtual Laboratory Details
Description: This animated virtual laboratory, produced by HHMI, that addresses concepts related to analytical immunoassay including the basis of humoral immunity,the foundation of ELISA, potential errors in conducting an ELISA and the sensitivity and specificity of a diagnostic test. This site has several layers including a laboratory notebook that provides experimental protocols for each step. This animation requires Shockwave to view, which is available as a free download.

Enzyme Kinetics Details
Description: This is site contains a comprehensive on-line introductory course on the concepts and techniques of steady-state enzyme kinetics. It has animated graphics (in Chime), and includes a discussion forum related to the topic. The site includes a fairly detailed discussion of the concepts and techniques used for measuring rates of steady-state enzymatic reactions, however transient measurements (i.e. stop-flow) are not discussed. This site will be most useful for bioanalytical students or biochemistry students desiring detailed background information on enzymatic reactions or the determination of kinetic parameters. Perhaps because of the animations, this site may be somewhat slow to access.

EPR Basics and Application to Biology Details
Description: This site contains a set of powerpoint slides that discusses the basic principles underlying electron paramagnetic resonance (EPR). The slides also present examples of the application of EPR to biological systems including organic radicals in proteins, paramagnetic metal centers and spin labels.

Exclusion Chromatography Details
Description: This site contains a brief description of the separation mechanism in size exclusion chromatography. The picture helps visualize the separation, but is a simplified and idealized presentation. A companion site, http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/A/AffinityChrom.html, describes affinity chromatography. The two sites together may be helpful in a biochemistry course where such techniques are used or discussed.

Experimental and Teaching Modules Details
Description: This site contains a set of experimental and teaching modules written by members of the European Advanced Light Microscopy Network (EAMNET). The modules are a mix of pdfs and websites that cover the fundamentals, history and practice of microscopy. The modules on microscopy, FRET, FRAP and Quantitative Multidimensional Microscopy will be of interest to chemists and biologists. Several of the modules include great graphics that would be helpful additions for instrumental analysis lectures.

Experiments in Electroanalytical Chemistry Details
Description: This website offers educators a set of eight classical electroanalytical experiments suitable for use in a quantitative analysis, instrumental analysis, or electrochemistry course. The materials should be useful for advanced undergraduates and beginning graduate students. Experiments include coulometric, conductometric, and potentiometric titrations, stripping analysis, flow injection analysis, and polarography. It is important to note that several of the experiments use mercury or mercury coated electrodes which present safety concerns.

Experiments in Electrochemistry Details
Description: This site is suitable for junior high and high school students. The website is clear and easy to use and develops the concepts in a clear and logical fashion, illustrating how Galvanic/Daniell cells work.

Flame Atomic Absorption Details
Description: In addition to being an introductory tutorial on Atomic Absorption Spectroscopy, the parent site has links to a variety of materials on environmental analysis.

Flow Injection Analysis Details
Description: This website by Monash University provides a primer for those who are beginners as well as those who wish to have a refresher on the principles and illustrative applications of flow injection analysis (FIA). The left hand menu allows selection of topics: FIA, Princples, Dispersion Process, Modes of Applications, Recent Developments, Bibliography and People in FIA. Schematics and illustrative signal outputs are provided for each FIa method. The site is easy to browse with links to subtopics. The site is unique in terms of bringing together in one place the basics of FIA with illustrations.

Flow Injection Analysis in the Undergraduate Laboratory Details
Description: This paper titled, Flow Injection Analysis in the Undergraduate Laboratory, by Rocha and Nobrega was published in the Chemical Educator. It describes two basic experiments. One is the measurement of copper using PAR reagent as carrier in a single line FIA system. Increasing the reaction coil length results in double peaks. Refractive index effects are demonstrated in the two-line system by adding ethanol. The second experiment is the measurement of phosphate with the molybdenum blue reaction in a three-line system. The effect of temperture is demonstrated, showing also the formation of bubbles at higher temperatures. The experiments are designed for a 4-hour laboratory. Unfortunately, the supplmentary PDF, which contains the schematic for the sliding-bar injector, is only available for Chem. Educator subscribers (or possibly by contacting the authors). This is a useful lab experiment for undergraduate quantitative analysis or instrumental course.

Fluorescence Correlation Spectroscopy Details
Description: The is material was previously published in as part of an online biophysics textbook. Although a date for publication is not provided, it must be before cell phones were widely used based upon the following: "Imagine trying to find out if a friend had left an overcrowded shopping center without a call to the info desk. Unless you are holding hands, this is next to impossible." With the exception of this funny piece of dated material, the scientific content of the article is rich and fairly complete. It begins with a nice history of FCS from Magde to Rigler and others. It outlines the instrumentation needed including very important information that is often left out of other reviews: the number of filters needed to block IR and back filling the objective. There are other nice details in the article: a discussion of 2 channel excitation in confocal microscopy, photobleaching in the focal volume only in two-photon microscopy, and how one can tune the two-photon laser for multi-color excitation. There is also a nice detail of the theory and math involved in autocorrelation and cross-correlation detection. The authors discuss the observables FCS can detect: number of molecules in the focal volume, brightness (aggregation), diffusion times, and the ability to differentiate between diffusion, active transport, anonomolous diffusion or convection. Overall, a very strong review of FCS for the first time FCS student, or as a refresher. It could be used for teaching notes to teach FCS in a course. Nice graphics as well.

Fluorescence Detection Animation Details
Description: This site is one in a series of sites with very good animations related to separations. This animation deals specifically with fluorescence detection for liquid chromatography. The animations are short (one to two minutes) and can easily be shown in class as part of a lecture. They are extremely helpful in illustrating key components and concepts of chromatographic systems. Users are encouraged to explore the site and the other brief animations as well. Separate links to other simulations by the same company (TRSL) are also listed on ASDL.

Fluorine NMR Details
Description: This article describes the use of fluorine (19F) NMR for the analysis and structure determination of biomaterials. Using a traditional text-with-figures format, the article gives an overview of the synthesis of 19F spin-labeled materials and detailed descriptions of 19F chemical shifts and relaxation phenomena as applied to both primary and tertiary structure determinations of biochemical interest. The article has a lot of practical iformation. Definitely a resource that someone considering using fluorine NMR should consult. This article will be most useful to advanced students. Prerequisites for this treatment of 19F NMR include introductory courses in NMR, organic chemistry, and biochemistry.

Forensic Science Laboratory Details
Description: This site has been accepted as the first on-line labbook in ASDLib. It presents analytical instrumentation in a forensic context, so that students learn both about quality measurements and the logic of combining results to draw conclusions.

Forensics in the classroom Details
Description: This site uses crime scene scenarios to introduce concepts of biology, chemistry, and physics in a way designed to excite interest in the applications of forensic investigations. Students conduct a variety of experiments including paper chromatography analysis, hair analysis, pH testing, fingerprinting, and handwriting analysis to experience forensic science technology. The site is a collaboration between the American Academy of Forensic Sciences and Court TV designed for middle and high school curriculums.

FTIR Spectrometry Details
Description: The site demonstrates principles behind the operation of the interferometer in an FTIR spectrometer. Graphics and interactive movies are used. Examples start from a single wavelength and build to the superposition of multiple wavelengths. The connection between an interferogram and a frequency domain spectrum is discussed.

Fundamental measurement PowerPoint Details
Description: This site contains good images of basic general chemistry lab equipment and how to use them to make measurements (graduated cylinders, burets, thermometers, and balances). It could be useful for introducing students to laboratory work and measurements.

Fundamentals of GC/MS Details
Description: This tutorial provides an excellent introduction into the fundamentals of GC/MS. The tutorial consists of five sections: An introduction of mass and types of ions, ionization modes, hardware, figures of merit describing mass analyzer performance, and qualitative methods of GC/MS analysis - including library searches. Each section contains animations or simulations of chemical and physical interactions that pertain to mass spectrometry such as gas-phase ionization processes, fragmentation, mass analyzers, the importance of a vacuum, and detectors. A basic introduction to gas-liquid chromatography is also provided. The tutorial is intended to describe GC/MS at an introductory level, but does include theory at an intermediate level, which may be included or not depending on the intended audience. Information is presented in a Powerpoint style, and each figure has a Details tab which provides additional information on the subject. This website has excellent pedagogical value for students and new practitioners.

Fundamentals of NMR Details
Description: This e-text presents an introduction to the fundamentals of NMR covering magnetic resonance, pulsed NMR, relaxation, chemical shift, spin-spin coupling, the nuclear Overhauser effect and chemical exchange.

Gas Chromatography experiment Details
Description: This site provides a Word document that describes a GC experiment involving the separation and quantitation of four butyl alcohol isomers. It has a complete background about the components of a GC instrument (with labeled pictures) and their functions. It has a section devoted to the measurement of response factors of the detector in use (here an FID). This would be a good experiment for a new faculty member to use as is, with slight modification to make it relevant to the particular GC system to be used.

Gas Chromatography Video Details
Description: This is a high quality video module demonstrating the basics of gas chromatography. Highlights include different GC instruments, detectors etc., as well as unique topics such as trouble shooting and interfacing the column that are not addressed in standard texts. This resource can be run (Shockwave Flash) from the home server or downloaded to your computer.

GC books Details
Description: This site contains a list of books about gas chromatography with their tables of contents. Potentially useful for practictioners or research students needing an introduction to GC. Some links (such as those to spectroscopy, NMR, and LC) do not yield any useful information.

GC coating animation Details
Description: This site is one in a series of sites with very good animations related to separations. This animation deals specifically with solute retention in GC. The animations are short (one to two minutes) and can easily be shown in class as part of a lecture. They are extremely helpful in illustrating key components and concepts of chromatographic systems. Users are encouraged to explore the site and the other brief animations as well. Separate links to other simulations by the same company (TRSL) are also listed on ASDL.

GC Electron Capture Detector Animation Details
Description: This site is one in a series of sites with very good animations related to separations. This animation deals specifically with electron capture detectors. The animations are short (one to two minutes) and can easily be shown in class as part of a lecture. They are extremely helpful in illustrating key components and concepts of chromatographic systems. Users are encouraged to explore the site and the other brief animations as well. Separate links to other simulations by the same company (TRSL) are also listed on ASDL.

GC Splitless Injection Animation Details
Description: This site is one in a series of sites with very good animations related to separations. This animation deals specifically with splitless injection in GC. The animations are short (one to two minutes) and can easily be shown in class as part of a lecture. They are extremely helpful in illustrating key components and concepts of chromatographic systems. Users are encouraged to explore the site and the other brief animations as well. Separate links to other simulations by the same company (TRSL) are also listed on ASDL.

GC/MS with animations Details
Description: This site contains a good review of GC detectors that is linked to animated files describing the hardware and principles of operation for GC/MS. From this site, one can also get to multiple other animations about a variety of analytical topics.

GEM: Greener Education Materials for Chemists Details
Description: This site is a resource for green chemistry principles and literature. It provides links for making green organic experiments and teaching the principles of green synthesis. Although it does not have many links specifically to chemical analysis, it provides an extensive overview and source of information regarding the important area of green chemistry.

GlobalFIA Details
Description: This site by GlobalFia provides a tutorial on the general aspects of flow injection analysis (FIA), sequential injection analysis (SIA) and the newly coined zone fluidics. Thus, it serves as an excellent resource for teaching flow methods to both undergraduates and graduate students, and as a refresher to practitioners. The tutorials are divided into 9 sections: introduction, fundamentals, dispersion, enrichment, chemistry, SIA, zone fluidics and bibliography. This modular approach makes information on concepts easy to digest and builds sequentially on each previous module with accompanying illustrative graphics. The bibliography provides references to hardcopy primary sources and a link to the FIA database at U. North Florida. The step-by-step instruction for the development of a new SIA method could be very helpful to someone who may be starting a new system or wishing to develop and new experiment. The site is easy to browse.

Green Chemistry (2nd edition) Details
Description: Measurement science used to characterize environmentally important species is a central aspect of this textbook and accompanying lecture support/PowerPoint presentations. In addition to discussing the hows and whys of measurement, the discussion of measurements up to 2007 as related to the future of the environment provides a context for learning the material.

Handbook of Basic Atomic Spectroscopic Data Details
Description: This is a NIST (National Institute of Standards and Technology) site containing atomic spectroscopic reference data. Information can be accessed through a variety of means, such as an interactive periodic table and dropdown lists of elements organized by name or atomic number. Data available include isotope abundance, electron configuration, nuclear spin, magnetic moment, ionization energies, spectral line wavelengths and intensities, and energy level information. References are also given.

Handbook of Operational Amplifier Applications Details
Description: The Handbook of Operational Amplifier Application is a complete and exhaustive compendium of Op Amp information. Chapters start with the basic electronics of the internal circuitry of op amps, feedback and analysis of operation followed by ideal and practical op amps. The remaining chapters provide numerous application circuits.

How People Learn: Brain, Mind, Experience, and School: Expanded Edition (2000) Details
Description: This page, in the National Academy Press website, gives the table of content of the book in the title of this site. As one of the "openbooks" from this press, the site allows one to search the book (approximately 400 pages) as well as download the complete book or selected portions of it. The site will be most useful to an analytical scientist interested in reading about current learning theories.

HPLC Details
Description: This video, distributed on YouTube by the Royal Society of Chemistry is on the basic principles of HPLC. This video is a short primer (~5 min) which introduces the basic technique and instrumentation. The theory of HPLC is described at a very basic level. Separation theory is presented in a qualitiative fashion, and both the mechanics and applications of HPLC were generally described. The ultimate strength of this video is the general nature of the content that makes it appealing to a wide audience. The video may be most appropriate in a lower-level general education science course (i.e forensic science) or as a quick orientation video for instrumental analysis students.

HPLC Tutorial 2,0 Video Details
Description: This high quality video resource focuses on partition chromatography. The video presents an overview of basic separation theory and discusses instrumentation and data analysis. The size of the video (62.6 MB) almost requires a high speed internet connection. The resource can be downloaded to the user's computer, which is recommended for those with slower connections.

HPLC, LC-MS, and FTIR sites Details
Description: This site contains a considerable amount of information on HPLC, LC-MS, and FTIR via linked sites by the same author and some vendor sites. It may require considerbale time to follow the links to find specific information, but as a collection of sites related to HPLC and FTIR it is quite useful as a teaching resource. There are some interesting animations that might be helpful for students to understand how these instruments work.

ICP Operations: A Guide for New ICP Users Details
Description: This site, written by Dr. Paul Gaines, is a handbook for ICP analysis. Topics such as matrix compatibility, quality control, spectral interferences, instrument operation (e.g. sample introduction, nebulization, etc.) make this an excellent practical yet concise manual on ICP operation. This manual is instructive not only for students and faculty interested in elemental analysis, but also for novice ICP analysts.

ICP-MS Details
Description: This site provides the principles of ICP-MS from sample introduction, ionization to MS quadrapole analysis. Excellent illustrative schematics of the main process in ICP-MS and pictorials of component parts. This has photos of the detector horn; photos of the actual quadrapoles; and of the plasma which are nice. The site has animations showing the nebulization (although not really related to any physical operation) and to the quadrapole. This material would serve as an excellent reference resource by students at the upper undergraduate and beginning graduate level. The detection levels for 27 elements are listed in a table.

Immunoassay, biosensors and other non-chromatographic methods for agrochemical analysis Details
Description: This site is a comprehensive 58 page book chapter in pdf format on nonchromatographic methods of analysis for agrochemical contaminants (residues). The process of preparing and testing immunoassay tests is also discussed. Both biological and physical-based methods are discussed. In the former, it presents a wide variety of methods including the use of PCR. In the latter, it includes spectroscopy and voltammetry.

Improving the Art and Practice of Amino Acid Analysis Details
Description: This site presents a very detailed tutorial on amino acid analysis. Topics discussed include analytical methods, calibration, hydrolysis, sample preparation, reduction of background and contamination, calculations and references. This site will be especially useful for faculty and students at all levels interested in bioanalysis and especially in the practical aspects of amino acid analysis.

Infrared Spectroscopy Details
Description: Introduction to Infrared Spectroscopy at the level of a freshman or sophomore textbook.

Instrumental Analysis Experiments Details
Description: Laboratory experiments for undergraduate instrumental analysis. Topics include data acquisition, control of instrumentation (gas chromatography, polarography, voltammetry, atomic absorption, robots), infrared spectroscopy, liquid chromatography, and nuclear magnetic resonance. Extensive use of LabView, Excel, and computers. Experiments are in PDF format.

Instrumental Analysis Laboratory Manual Details
Description: This online instrumental analysis lab manual Illinois State University contains experiments in chromatography, mass spectrometry, electrochemistry, electronics, spectrophotometry, and atomic spectrometry. Many of the experiments in this manual may be used with little or no modification of instrumentation commonly found in well-supported chemistry departments. The authors focus on the optimization and characterization of the experimental response for techniques such as GC (van Deemter curves, temperature programming), HPLC (effect of mobile phase pH on retention) and flame AA (effect of slit width and burner parameters). In addition, there are two experiments, "pH and [F-] Measurements with a Homemade Meter" and "Construction of a Simple Spectrophotometer" which introduce the student to breadboarding simple op-amp circuits in order to perform electrochemical and spectroscopic measurements. These two experiments require little capital investment and could be adapted for an undergraduate electronics lab as a final project. Finally, the on-line lab manual has resources which focus on the use of Microsoft Excel and good examples of what to do and what not to do when writing lab reports.

Instrumentation on the web Details
Description: Discussion of teaching instrumentation using animations many of which are produced by the authors. Numerous links and many instrumentation animations.

Integration of Environmental Analytical Chemistry with Environmental Law: The Development of a Problem-Based Laboratory Details
Description: This JCE paper is well written, generous referenced and will serve as an excellent reference for anyone interested in adapting and implementing this problem-based approach to an upper-level environmental analysis laboratory that emphasis QC/QA and performance-based analytical methods. As such it would be a fine addition to the ASDL collection.

Interpreting Electrospray Mass Spectra Details
Description: This site is a tutorial on interpretation of electrospray mass spectra of multiply charged molecules. It provides a simple explanation of the electrospray process and the potential for the creation of multiply charged species, especially when working with peptides. The mathematics of determining the charge state and molecular weight of the peptide is also explained. Although this site provides a good foundation on electrospray MS of peptides, students requiring an advanced understanding of MS fragmentation of proteins and peptides will have to go elsewhere.

Introduction to AFM Details
Description: Excellent introduction to the technique of atomic force microscopy at a level suitable for undergraduates. The page describes the basic modes (constant force, tapping, lift mode) and explains the significance of the tip and tip effects in imaging.

Introduction to Capillary Electrophoresis Details
Description: A comprehensive overview of capillary electrophoresis and its closesly related variants. This pdf document details both theoretical and practical aspects of CE, and includes an application index and thorough bibliography. This material is appropriate for beginners or new practitioners of CE, and would be an excellent resource for instruction in instrumental techniques.

Introduction to Chemical Equilibria Details
Description: An interactive set of applet-based demonstrations (many modeled as experimental measurements) that illustrate the concepts and calculations of chemical equilibria. The site demonstrates equilibrium processes in a reaction vessel by plotting the concentration of reactants and products over time. The site would be a good supplement for a class in general chemistry or quantitative analysis.

Introduction to Chemical Equilibria Details
Description: An equilibrium-oriented web site that presents the concepts of chemical equilibria. It presents notes on general equilibrium topics that include reversible reactions, reaching equilibrium, dynamic equilibrium and factors that can affect equilibria. The explanations are brief, but generally complete. In addition, the site has some self-quiz questions.

Introduction to Dynodes Details
Description: The sight is presented as a guided exploration into the operation of a photomultiplier from the first light incidence to the output signal. Questions guide the exploration and allow (sometimes require)the student to speculate on the result before going forward. A careful, patient student will get a thorough introduction to the operation of a dynode and how to bias it.

Introduction to Mass Spectrometry Details
Description: An introduction to mass spectrometry, primarily an overview of ionization methods and mass analyzers with diagrams that provide visualizations of the topics discussed.

Introduction to Mass Spectrometry Details
Description: This site contains an on-line text on mass spectrometry at the intermediate level. The text gives good general coverage of mass spectrometry instrumentation and applications in very readable format. It contains nice diagrams that provide a visualization of the ionization and mass selection processes. It also contains an overview of applications of mass spectrometry near the end that is different than most sites related to MS. It is especially appropriate for intermediate students.

Introduction to Scanning Probe Microscopy Details
Description: This learning module teaches the principles behind scanning tunneling microscopy and atomic force microscopy. The module includes example applications and ample literature citations.

Introduction to Signals and Noise: eLearning Module Details
Description: Basic concepts of signals, noise, and extraction of data from noisy signals are presented as an e-learning module. Excel spreadsheets allow students to vary noise parameters. Basic electronics ideas relating to RC circuits support introductory information on filters

Introduction to X-ray Diffraction (XRD) Details
Description: This learning module presents the fundamentals of X-ray Diffraction for characterizing molecular structure in a form useful both as lecture notes and for self-study.

Introductory Tutorial to Mass Spectrometry Details
Description: An introduction to GC-MS for beginning students in analytical or organic chemistry lab. The site includes discussion of quadrupole mass analyzers, ionization, detection, and interpretation of mass spectra. One of the best features of this site is a series of on-line quizzes on the interpretation of EI mass spectra that includes hints as well as explanations of why the answers are right or wrong.

Ion Exchange Chromatography Details
Description: This website contains aN ion chromatography simulator that can be run on-line or can be downloaded. The simulator focuses on separations of Proteins using Ion Chromatography. Also included is hyperlinked reference information, an example of a homework assignment using the simulator, and some information on protein structures.(note this is an archived version of this site, as the original has been moved).

IR Helper Details
Description: The website uses JCAMP formatted spectra, and javascript to lead the user through the analysis of IR spectra. The software asks the user a series of questions about the spectrum, and provides correction if the user answers incorrectly.There are 18 different spectra to choose from, from simple alkanes to a few fairly tricky assignments.

Kinetic Capillary Electrophoresis(KCE): A conceptual Platform for Kinetic Homogeneous Affinity Methods Details
Description: Kinetic Capillary Electrophoresis is a family of methods for studying binding of biopolymers, measuring rate constants, binding constants, and in some cases providing mechanistic details. This Online Article is a presentation by the originators of this family of techniques ready for classroom or independent use.

Laboratory Orientation and Testing of Body Fluids and Tissues for Forensic Analysts Details
Description: This web site is part of the President's DNA Initiative and is devoted to an overview of historical and contemporary techniques to characterize body tissues. The first part of the course covers basic laboratory procedures, safety requirements for laboratory personnel and emphasizes quality control and quality assurance in the laboratory. The second section deals with serological techniques for characterizing specimens such as saliva, semen, blood and urine Identification and individual utilizing polymorphic enzymes are also covered. The site is designed as an on-line short course with excellent graphic support. The user must register and secure a readily obtainable password prior to entering the site.

LabVIEW for Instrumental Analysis Details
Description: This site provides two useful resources for instructors and students of analytical chemistry. The first is a collection of Labview virtual instruments(VIs)for demonstrating topics such as signal-to-noise ratios, boxcar and ensemble averaging, power spectra, digital filtering, analog-to-digital conversions, and the Nyquest frequency. For users that do not have a working copy of Labview, executable versions are included that use Labview's free run-time engine (Windows only). The second set of resources is a series of tutorials for teaching students how to write their own VIs. The tutorials are well thought out and nicely build on each other.

Landmark Instruments of Chemistry Details
Description: This website effectively uses animated movies combined with text explanations to describe the processes in FT-IR interferometry, TLC, GC and magnetic sector mass spec. It is effective in illustrating processes that are otherwise difficult to visualize. These materials are excellent visualization tools that can be incorporated into lectures readily.

Laser-induced Remote Sensing for Chemistry and Micro-imaging Details
Description: This site describes an LANL project to develop laser-induced breakdown spectroscopy for elemental analysis and remote sensing on Mars.

Lead in DC Water Details
Description: This site is a PowerPoint presentation describing the problem with lead in Washington, DC, drinking water. The presentation is interesting and well illustrated. It contains a discussion of the basic chemistry involved with this problem. It is potentially useful for a broad range of interests from high school through university level courses in environmental chemistry. It does not contain any significant amount of material on chemical analysis (lead determinations in water are well covered in other sources), but provides excellent rationale for the necessity of doing lead analyses in water.

Learning Module: What Chemists need to know about copyright Details
Description: This website, developed by ACS Joint Board/Council Committee on Copyrights, provides a learning module for chemists to learn about the legal aspects governing copyright and what constitutes copyright material. It contains a set of five useful resources: (1) an html learning module about copyright for chemists; (2) a set of questions faculty could use to test students' understanding of copyright; (3) a summary of copyright policy; (4) a pamphlet (pdf file) that could be handed out to a class for discussion; and (5) a copy of the ACS copyright transfer form (pdf file) that ACS publications use.

Learning to Learn: An Introduction to Capillary Electrophoresis Details
Description: This article describes a problem based learning approach to analytical chemistry labs using capillary electrophoresis as the instrumental method. The on-line link requires a password for The Chemical Educator to get the full article. The article also describes a lab that is an example of problem based learning. Students, playing the role of lab technicians, learn how to use the instrument in order to perform an analysis.

Lecture Notes On Forensic Law Details
Description: This site offers lecture notes relating to an introductory survey course on forensic science. It is designed to provide a comprehensive understanding and analysis of technical and legal issues involving forensic techniques. The lectures, focus on traditional subjects relating to the services of crime laboratories,but also deals with allied subjects,including forensic psychiatry, forensic pathology, and social science.

Linear and Cyclic Voltammetry Details
Description: This website provides an introduction to linear sweep and cyclic voltammetry. The shape of the current-voltage curve for these techniques is explained with illustrations of the concentration profiles from the electrode surface into the solution at different stages of an electrochemical reduction.

Liquid Chromatography Books Details
Description: This site provides a list of books related to liquid chromatography and its applications. While not immediately pedagogically useful, it may be useful to those seeking texts about LC for their own research interests or to provide as references to students.

Method OIA-1677 Available Cyanide by FIA, Ligand Exchange and Amperometry Details
Description: This is a pdf version of an official EPA method for the analysis of cyanide. It discusses a variety of quality control procedures a wide range of controls that must be used for method maintenance and development. Within the context of teaching, this site could be viewed as unique in allowing students to work through all contingencies that must be moniitored for a measurement to be deemed valid. It defines and contains a variety of control parameters with mathematical descriptors. The chemistry for the flow injection analysis of cyanide is provided as well as a diagram of the instrumental setup. Cyanide is widely dispersed in the environment and its analysis should be of interest to students.

Micro Separations Distance CE Details
Description: This site describes how to assemble an inexpensive, yet reliable capillary electrophoresis apparatus and provides experiments to demonstrate electrodynamically-driven separations. Good background material about CE theory is provided.

Micro- and Nano Technology, 1st Int'l Symp 2004 Details
Description: This site offers concise and readable description of three new biosensing technologies that are absent from textbooks. The technologies developed at Oak Ridge National Laboratory include: 1) use of nanoprobes based on plasmon-resonance (which is defined) to enhance surface Raman scattering and fluorescence; 2) an optical neurosensor based on a 40 nm fiber optical tip; and 3) a multifunctional biochip capable of DNA and other protein-based bioassays. The article is written in PDF format with several illustrative graphics. Although insufficient in details to duplicate experimentally, the article does provide a nice overview of how development of small-scale analytical measurements can be used to address important biological problems. This 6 page article is a paper that was presented at the 1st Int'l Symposium on Micro and Nano Technology in 2004. A list of references appear at the end.

Multiple Regression Details
Description: This site, which is part of an on-line master’s level course from Manchester Metropolitan University, provides a solid introduction to the use of multiple regression. The presentation is logical and thoughtful, beginning with a glossary of important terms and then taking the reader through a review of bivariate regression, a series of seven guidelines for multiple regression, and the implementation and interpretation of multiple regression. The site includes one worked example that, although biological in nature, is easily accessible to students of analytical chemistry. One limitation to the site is its reliance on Minitab for calculations, which may not be available to students. Users, however, should not have a difficult time reproducing the calculations using other software packages, such as SPSS or Excel. Prior knowledge of the basics of bivariate regression is assumed; thus, the site is most appropriate for advanced undergraduates and graduate students.

NMR Spectroscopy Tutorial Details
Description: This is a straight forward elementary approach to proton and carbon NMR analysis targeted at students who are just at the most beginning stages of NMR spectroscopy, for example those in a first-semester organic chemistry course. There are some good descriptions of the most basic aspects of NMR spectroscopy such as coupling and some very simple structure problems to solve that are useful to students at the most introductory level of NMR spectroscopy.

NMR animation Details
Description: This site has very nicely animated tutorials on NMR with sufficient depth to be useful to the non-NMR savvy. The animations are accompanied by short descriptions so that the processes displayed can be understood by the viewer. This site goes beyond just showing precession. There are nice animations showing the effect of different pulses, including composite pulses on the magnetization, the effects of magnetic gradient pulses to measure diffusion and do coherence pathway selection. Other aspects are less useful since they basically just present material that could be found in a book in an animated format. The site is useful for teaching in a lecture setting. Students will find the images appealing.

NMR of Paramagnetic Proteins Details
Description: This site presents an overview of techniques used for structural elucidation of paramagnetic metalloproteins. In the first section experiments for detection and assignment such as COSY, TOCSY, HMQC, 1D NOE, NOE-NOSEY, superweft-NOESY, EXSY and deuterium labeling are discussed in terms of their application to paramagnetic proteins. The NOE-NOESY and superweft-NOESY experiments are of particular interest because of the way they take advantage of the relaxation differences between those protons near the metal center and those further away. The NOE-NOESY allows the mapping of connectivities between broad and hyperfine shifted signals and the signals in the diamagnetic region of the spectrum. The superweft-NOESY is used to enhance connectivities between fast relaxing protons. The remainder of this section focuses on the magnetic susceptibility tensor and its anisotropy and direction. The next section deals with converting the experimental observations into distance constraints for input into structure refinement software. A nice step-wise approach is described that results in relatively accurate structures of paramagnetic metalloproteins. The final section addresses the state of NMR of paramagnetic molecules at the time of publication and notes more recent applications of structural constraints derived from hyperfine coupling and the observation of partially oriented systems due to anisotropic magnetic susceptibility. This manuscript jumps head first into the topic at hand citing examples and discussing the application and peculiarities of the various experiments. This leads to a nice discussion of the various types of distance constraints based on hyperfine coupling (contact, pseudocontact and relaxation-based) their extraction from the data as well as the improvements each brings to structure refinement pertaining to location of the metal ion. The content is directed to the more advanced NMR user and would be suitable for an upper division or graduate level NMR class.

NMR Spectroscopy Details
Description: This site contains web-based programs that allow the user to predict chemical shifts, spin-spin coupling patterns and NMR line shapes affected by dynamic chemical exchange. This site will be most useful for students with a good background in the fundamentals of NMR theory.

NMR Spectroscopy - Theory Details
Description: This web site begins with a simple quantum description of NMR and proceeds to introduce resonance absorption, relaxation, chemical shifts, and scalar couplings. This site will be useful for advanced undergraduate students needing a description of NMR that is more detailed than that given in most introductory Organic texts.

NMR Spectroscopy: Lab 8 Details
Description: A complete NMR laboratory exercise from a set of fifteen (15) experiments in various topic areas developed for a physical chemistry laboratory at New Mexico State University. Excellent introductory material is provided, along with links to additional sources of information, including NMR tutorials. Pre-lab questions are presented along with detailed laboratory procedures. The two part experiment has students first measure proton spectra for a set of unknown substances and to match the spectra with the compound in a list provided, followed by a kinetics measurement. While the procedure is specific to Varian instruments, users should be able to easily modify the parameters to their own instrument. Site authorization is required to use some of the embedded links, but even without that access, this experiment should be of interest to instructors in both instrumental or physical chemistry.

NMR tutorial Details
Description: The introduction to this site provides an entry-level introductions to NMR in a text + figures format. The site also contains two example structure elucidation problems using NMR. IR and MS data complete with hints and answers. Although the molecules are pretty simple, the examples do a good job of illustrating the structure elucidation process. The site also has data for 5 more complex structure determination problems.

Nuclear Magnetic Resonance Spectroscopy Details
Description: This website serves as a primer for understanding the fundamentals of NMR spectroscopy. Plenty of useful figures and animations that enhance the understanding of nuclear spin, shielding, and how these phenomena serve as the basis for NMR.

Ohio State University General Chemistry Test Bank Details
Description: A comprehensive set of test bank questions is offered to reinforce concepts in a general chemistry course. Test banks 11-14 cover topics related to analytical chemistry including electrochemistry.

Optics Tutorial Details
Description: For those wishing to design optical instruments or understand why an optical instrument was designed a particular way, this site explains the engineering details in more depth than typical textbooks.

Organic Chemistry On Line Details
Description: This site covers introductory material related to the analysis of small organic molecules by mass spectrometry, uv-visible spectrophotometry, IR spectrophotometry, and nmr spectroscopy. A concise explanation of each approach is presented with illustrations. This would be useful for those teaching organic chemistry and for others who need a review of the topic. It is treated from the standpoint of the phenomenon related to the measurement and the results one would obtain. It does not present much detail on the instrumentation. The section on Spectroscopy Resources at the end of the site contains a list of links to additional information plus a several links to compilations of problems (and their solutions) that challeng the student to interpret NMR or IR spectra.

Organic Structure Elucidation Workbook Details
Description: This web site contains 64 structure elucidation problems for the qualitative analysis of organic compounds. For each problem the empirical formula, molecular weight, 500 MHz proton and 125 MHz carbon NMR spectra, IR and mass spectral data are presented. The problems are categorized as easy, moderate or difficult. Students in introductory Organic Chemistry who want practice identifying unknown compounds should find this site useful. Instructors looking for exam or classroom problems for students at this level could also take advantage of the information on this site.

Origin of Chromatography Details
Description: This site has a series of links to QuickTime movies that animate the chromatographic process. The movies show the effect of changing K, L, and N on peak width and separation. The site is useful in combination with other sources that explain the background theory.

Overview of Scanning Probe Microscopy Techniques Details
Description: This manufacturer's site offers a brief, readable, and well-illustrated introduction to several important methods in scanning probe microscopy (SPM), including STM, AFM, and NSOM. "Education links" include 3-d animations from surface scans utilizing these techniques. An excellent "Suggested Reading" section contains links to on-line texts and references to books covering SPM and other topics in nanoscience.

Paper Chromatography Details
Description: This site is a very brief introduction to the idea of separation of components in a mixture and a set of instructions for students for separating colored compounds by paper chromatography (on coffee filters). The appropriate audience would be students in a high-school or introductory, non major's college chemistry class.

Paper Chromatography of Stains Details
Description: A paper chromatography experiment separating dyes. The experiment is targeted toward 8-12 grades, but could be suited to an introductory chem laboratory section.The text of the site contains instructions for setting up and executing the experiment in a large class setting.

pH Calculation Details
Description: This pair of pH calculation programs serves as an excellent tool for anyone wishing to calculate the pH of a solution containing multiple acids and bases. These programs allow practitioners to predict the pH of simple and complex acid/base solutions and buffers. Users are encouraged to carefully read the guides provided by the author.

Photodetectors and Fiber Optics Details
Description: Power point slides to support a lecture on the principles and usage of photodiodes and optical fibers for sensors and instrumentation. There is no supporting text for the slides.

Physical Chemistry Online Details
Description: Physical Chemistry Online (PCOL) Is a collection of physical chemistry modules that address specific concepts in an open-ended, collaborative fashion. The PCOL collection contains fifteen guided inquiry modules covering five broad topics: thermodynamics, kinetics, polymers, computational chemistry, and spectroscopy. Many modules provide the students with an industrial context auch as the evaluation of raw materials or the development of new products. Students that participate in these modules are expected to work with their peers in a collaborative fashion and encouraged to share their results with groups at other participating institutions. The website contains an Instructor Handbook that provides the History Of PCOL, Module Development, and Ideas/resources related to implementation, facilitation and assessment. There are also tutorials that serve as background information for various PCOL modules. There are occasional problems with broken links on this site. For example, athough the index is supposedly searchable by the first letter of the topic, clicking on the letter brings the user to a dead end (broken links page at Monmouth University). Overall, this is a valuable resource for those faculty members interested in providing a guided inquiry and collaborative experience for physical chemistry students.

Population Genetics and Statistics Details
Description: This website is part of the President's DNA Initiative and is devoted to past and current methods of macromolecules such as DNA. This website introduces the student to the subject of population genetics and stresses factors that can alter allele frequencies in a population and calculations associated with the Hardy-Weinberg principle. The student will learn to use acceptable statistical approaches to evaluating DNA data and how DNA databases are constructed and applied. This site is designed as an on-line short course with excellent graphic support. The user must register and secure a readily obtainable password prior to entering the site.

Potentiostats Details
Description: This PDF document (52 pages) provides a comprehensive discussion of background history, theoretical considerations, electronic circuitry and design of potentiostats. Subject is treated in depth not found in textbooks, although computerized formats are not included.

Prediction of Chemical and Biological Properties of Organic Compounds from Molecular Structure Details
Description: This website is a PDF file of 32 slides and accompanying notes that describe the process of determining quantitative structure activity relationships. The slides focus on the ADAPT software, but are generally useful to anyone interested in QSAR, and discuss the details of Structure Entry and Molecular Modeling, Descriptor Generation, Feature Selection, Model construction, and Model Validation.

Principal Component Analysis Details
Description: This site, which is part of an on-line master’s level course from Manchester Metropolitan University, provides a solid introduction to principal component analysis. The presentation is logical and thoughtful, beginning with a glossary of important terms and then taking the reader through the process of completing a principal component analysis. Two particularly impressive parts of the site are the explanation of projecting higher dimension data to a lower dimension, and a graphical explanation of principal components. The site includes three worked example that, although biological in nature, are accessible to students of analytical chemistry. One limitation to the site is its reliance on Minitab and SPSS for calculations, which may not be available to students. Users without access to one of these programs will need access to another software package, such as the freeware program R. Prior knowledge of basic statistics is assumed; thus, the site is most appropriate for advanced undergraduates and graduate students.

Principles of Scanning Probe Microscopy Details
Description: This site offers a beautifully illustrated introduction to the principles of scanning probe microscopy. The text is interspersed with links to additional information, much of it from the Interface Physics Group at Leiden University. There are several included animations and links to picture galleries which illustrate both principles and utilization of scanning probe microscopy. An additional "links" page takes the user to sites of research groups involved in ongoing developmental work in surface science.

Quality in Environmental Analysis Details
Description: Although this website by the U.S. Geological Survey (USGS) does not contain analytical data or methods per se, it is one that contains a complete compendium of links to material on environmental topics under the pervue of USGS. As such, it can serve as a resource and background material for students, faculty or practitioners interested in learning about environmental issues. For example, there is a link to Hg in the environment that discusses the sources, chemical composition and consequence of Hg as related to land or water species. This site is a library of links to USGS articles and reports, some of which may not open. Otherwise, it is easy to browse and link to topics of interest.

Quantitative Chemical Analysis, 6e Details
Description: This is a site with material related to Dan Harris' textbook. It is not as general as some sites but the material is of high pedagogical value. Short tutorial sections are available for many topics with extensive web linkages. "Living" graphs and Excel files illustrate important material such as pH fractional composition and statistical analysis. Students can take practice quizzes on material from the text. Full Powerpoint slideshows include nearly all of the figures contained in the text. Full set of laboratory experiments are available. Some material is not available without registering as a user. Some menus are hidden beneath buttoms of windows, and are sometime difficult to utilize. Once mastered, the site works well. The most likely users of this site are teachers and students who may be using Harris' textbook, as much of the material is keyed to it, but others may also find it useful.

Quantitative NMR Details
Description: A learning module focused on principles and practice of NMR for quantitative analysis, an application less commonly associated with the technique than is structure determination. Links to simulation packages are included.

Radioanalytical Chemistry Details
Description: Course on the use of radionuclides in analytical chemistry. Types of radioactive decay are discussed as well as the techniques of scintillation counting, neutron activation analysis, and gamma spectroscopy.

Redox Potentiometry Details
Description: This site contains materials from a lecture course in Biophysics, covering activity, free energy, equilibrium constants, and effect of pH on redox potentials, potentiometry, and reaction rates. The redox-specific content is based on interesting biological reactions not often found in chemistry texts.

Reliable Measurements: A Guidebook for Trace Analysts Details
Description: Written by Dr. Paul Gaines from Inorganic Ventures, Inc., this website provides a comprehensive resource on sample preparation and analysis for those interested in elemental determinations by atomic spectrometry, especially ICP-OES and ICP-MS. Issues such as sources of contamination, detection limits, sample preparation, standard stability, and method validation are well covered on this website. An excellent set of references is also provided.

Reverse Phase HPLC Basics for LC/MS Details
Description: This site provides a tutorial on practical reverse phase chromatography for LC-MS. Focusing on peptide and protein analysis, Andrew Guzzetta offers appropriate tips on mobile phase gradients, preparing your reversed-phase HPLC column for the first run of the day, and taking care of your column after the day's separations are complete. The site also provides a representative list of web-based resources on LC.

Reversed Phase HPLC Mechanisms Details
Description: This is a Powerpoint Presentation on reversed phase mechanisms in HPLC. It includes a good but superficial discussion of reversed phase mechanisms and would expect the user to provide the depth. Instructors may find it helpful as an outline for a lecture on HPLC.

RSC.org: Gas Chromatography Details
Description: This video, distributed on YouTube by the Royal Society of Chemistry is on the basic principles of GC. This video is a short primer (~5 min) which introduces the technique and instrumentation. There are many assumptions that are made in the presentation of this material, due to the fact the video is meant to be a basic introduction. Examples of such assumptions include the statement that volatility solely controls the elution order of volatile compounds on a GC column and that concentration is the only parameter that controls the relative response of a compound for a given GC detector. The ultimate strength of this video is the general nature of the content that makes it appealing to a wide audience. The video may be most appropriate in a lower-level general education science course (i.e forensic science) or as a quick orientation video for instrumental analysis students. The GC-FID and GC-MS are highlighted.

RSC.org: IR Spectroscopy Details
Description: This video, distributed on YouTube by the Royal Society of Chemistry is on the basic principles of infrared spectroscopy. This video is very useful for a newcomer to IR. The video highlights important basics to the technique. The "top-off" look of the instrument and use of a common real-life sample to demonstrate the instrument is quite useful. This site is a thorough primer at a basic level. The short video (6.5 min) would be useful in a classroom setting or students on their own interested in the technique.

RSC.org: Mass Spectrometry Details
Description: This video, distributed on YouTube by the Royal Society of Chemistry is on the basic principles of mass spectrometry, using a magnetic sector instrument to demonstrate how specific m/z ratios can be selected. The theory and operation of MS, including the chemistry of ionization and fragmentation is described at an introductory level. There's also an excellent example of the use of high resolution MS to differentiate between nominal mass and actual mass. The video does a very good job of explaining the concept such that only a little background knowledge is required. The video is short enough (6 mins), that it would be very useful in a class setting or for students outside of class. The ultimate strength of this video is the general nature of the content that makes it appealing to a wide audience. The video may be most appropriate in a lower-level general education science course (i.e forensic science) or as a quick orientation video for instrumental analysis students prior to introducing mathematical or operational concepts. This video would also be helpful for a lay science person who wishes to learn more about mass spectrometry from a general interest perspective.

RSC.org: Proton NMR Details
Description: This video, distributed on YouTube by the Royal Society of Chemistry is on the basic principles of NMR. This video is a good primer and would be very useful to supplement introductory lectures on NMR. The video covers the basic theory behind a 1H spectrum and goes through actually acquiring a spectrum. The “top-off” look of the instrument is useful and how the superconducting magnet is mounted. Good for a basic introduction.

RSC.org: UV/Vis Spectroscopy Details
Description: This video, distributed on YouTube by the Royal Society of Chemistry is on the basic principles of UV/Vis. This video is a good primer (~5 min) and the “top-off” look of the instrument is useful in explaining components. A double beam instrument is described in this video.

Separation Science Animations Details
Description: This site from TRSL is the main site that links to many animations related to how chromatography systems work. Most of the animations are quite good and would be helpful to students when trying to visualize what occurs in an instrument during a separation (e.g. injection, detection, etc.).

SIMS Animation Details
Description: Watch simulations of atoms and molecules colliding with a metallic matrix. See crystal structures disrupted and atoms sputtered.

SPECTROPHOTOMETRIC DETERMINATION OF ASCORBIC ACID IN ... Details
Description: This is an article describing the flow injection analysis of ascobic analysis using iron phenanthroline as a redox reagent with following UV vis detection. Although this paper is from the primary literature, the material is presented at a level that can be understood by undergraduates. It provides a good illustration of the factors affecting the quality of flow injection analysis and illustrates how a analytical method is optimized. The material is discussed in sufficient detail that a class could repeat the exercise or complete a problem set based on this article

Spectroscopy Details
Description: This website describes the theory and practice of IR and NMR spectroscopy for classroom and laboratory instruction. Although it is written for a course at the University of Colorado, Boulder, this site is appropriate for anyone doing analytical measurements with infrared or NMR. Its contents is comprehensive with excellent and straightforward illustrations.The website incorporates several tutorials on IR and NMR theory. In addition, it presents sample energy calculations and both pdf and Powerpoint files that describe IR and NMR in detail. There are also links to spectral databases.

Split Injection GC Details
Description: This site is one in a series of sites with very good animations related to separations. This animation deals specifically with split injection in gas chromatography. The animations are short (one to two minutes) and can easily be shown in class as part of a lecture. They are extremely helpful in illustrating key components and concepts of chromatographic systems. Users are encouraged to explore the site and the other brief animations as well. Separate links to other simulations by the same company (TRSL) are also listed on ASDL.

SPR : Surface Plasmon Resonance Tutorial Details
Description: This website provides a straightforward introduction to the fundamentals of SPR, the genesis of the plasmon and the evanescent wave, and how SPR can be used to monitor the chemical nature of species adsorbed to the surface of a metal substrate. It provides a good tutorial on a subject just getting to the textbooks.

SPR and Related Calculations Details
Description: Computation of Surface Plasmon Resonance using common surfaces (gold, silver, copper) and wavelengths (632.8 nm) is done on-line. The site is maintained for researchers and students alike.

Spreadsheet Simulations for Analytical and Physical Chemistry Details
Description: A collection of Microsoft Excel spreadsheets that illustrate fundamentals of analytical and physical chemistry. Such fundamentals include acid-base titration curves, ionic strength and activity coefficient calculations, solubility calculations, harmonic oscillator potential wells, Maxwell distributions, and an equation calculator. There are also links to other chemistry spreadsheet resources.

Study of Electrode Mechanism by Cyclic Voltammetry Details
Description: This lab experiment uses cyclic voltammetry to determine the concentration of acetaminophen (active ingredient of Tylenol) in a children’s pain relief elixir and to study the pH dependent mechanism of its oxidation. The experiment includes theory, pre-lab, write-up instructions and reference article.

Surface Science Forum Details
Description: Extensive information about all forms of surface analysis including detailed information on analytical techniques, online tutorials, reference data, conference information, news and links to other resources.

Surface Science Tutorials Details
Description: The Surface Analysis Forum contains tutorials, databases containing reference values important for many surface analyses, and a glossary for surface science technique acronyms. The tutorials are really on-line courses offered in specific aspects of surface analysis. All are presented in a clear fashion. In addition, there is a link to software (much of it free and downloadable) for data analysisThe site is structured for teaching and is easy to read.

Synthesis of a Sonogel-Carbon Modified Sensor Electrode with Titanium Oxide (TiO2) to Detect Catechol Details
Description: This experiment demonstrates cyclic voltammetry, surface modification, selectivity, and bioanalysis in assaying catechols in the presence of ascorbic acid. Pre- or post-lab questions are included, along with sample student data and instructor’s notes.

The Basics of MRI Details
Description: This web site is an on-line textbook describing the principles of magnetic resonance imaging (MRI). The treatment is often quite mathematical, but the site also reviews all of the mathematics and physics needed to understand the material. Approximately forty clinical images can also be found on the site. This site is appropriate for students needing a stand-alone introduction to MRI.

The Fluoride Ion Selective Electrode Experiment Details
Description: This is an experiment for the determination of fluoride ion with an ion selective electrode (ISE). While some experimental guidelines are given, students are left to choose appropriate standard concentrations and sample type, and to develop their own experimental procedure.

The Paradigm Laboratory Project Details
Description: This project plans to develop problem-based inquiry learning laboratories that have science majors in introductory chemistry laboratories transfer an understanding of the attitudes and methods of scientific inquiry to knowledge and experiences in their disciplines of study.

The Practical Application of Light Details
Description: This commercial website is a good tutorial on optical design. While users should know a few freshman physics ideas about the nature of light and imaging, the novice optical designer can start from scratch using the material provided by Melles Griot.

Titration of an Unknown Acid or Base Details
Description: This website contains a JAVA applet that simulates the titration of an unknown acid or base, and provides a graphical output of the titration curve. The unknown compounds are taken from a list of amino acids. Students set up the parameters of the titration, and then create a simulated pH curve. From this they are able to identify the unknown compound from the list, and determine the acid dissociation constant(s) from the titration data.

Tunable Monochromator Movie Details
Description: The Quick Time movie illustrates and describes to operation of a Czerny-Turner Monochromator. The slits, mirrors, grating and grating scan are described in the production of a wavelength at the outlet slit. The movie is a companion to the Double Beam Spectrometer.

Understanding NMR Details
Description: This site provides links to a series of pdf files that represent chapters of an e-text on the basics of NMR. While many textbooks on NMR are available the chief merit of this one is that it has a nice chapter on the NMR instrument (ch. 5) which should be accessible to undergraduates. The text also provides a relatively mathematics-free or maybe more accurately Dirac bracket notation-free introduction to 1-D and 2-D (COSY and NOESY) experiments that would be appreciated by advanced undergraduates or beginning graduate students involved in undergraduate research experiences using NMR

Videos zur Titration und Gravimetrie (Titration and Gravimetry Videos) Details
Description: This website provides a set of short videos which demonstrate to quantitative analysis students the basic steps and visual changes encountered for the following experiments: Mohr titration (for chloride), acid-base titrations, and gravimetry for iron and nickel. A cursory knowledge of German is needed. However, individuals with some knowledge in these techniques can interpret these videos with little trouble. Real Player (or other software that can play .ram files) is required.

VMSL: Virtual Mass Spectrometry Laboratory Details
Description: This site presents a series of case studies that can be explored using modern mass spectrometry methods. The problem-solving nature of the site provides students a virtual laboratory experience that can supplement access to mass spectrometry instrumentation.

WebSpectra - Problems in NMR and IR Spectroscopy Details
Description: This web site provides thirty beginning, twenty-nine intermediate, and sixteen advanced NMR structure analysis problems and their solutions. For every unknown a proton and a carbon spectrum are provided. Many of the more advanced problems contain COSY and DEPT spectra as well. A particularly useful feature of this site is that the user can zoom into spectral regions in all of the spectra.

X-ray Diffraction Details
Description: This Site Is A Good Freshman Or Sophomore Level Introduction To Diffraction And Its Application To Studying Crystal Structure. Because It's Very Visual And Interactive, It Engages The Student. It's Not Mathematical Enough For An Upper Level Course. The basics of diffraction are covered with excellent interactive demos. Demos are great as a supplement but not as a stand alone module on diffraction.