ASDL-Analytical Sciences Digital Library


Your search results for Technique returned 239 results.
	Analytical Electrochemistry: A Laboratory Manual	Details
	Description: This labware module contains directions for seven experiments in analytical electrochemistry. The experiments are designed to illustrate fundamentals of electrode reactions as applied to readily accessible redox reactants. They provide insight to dynamic electrochemistry for scientists at all levels of training. Activation procedures to prepare glassy carbon electrodes are provided in a TechNote.
	2D NMR Spectroscopy	Details
	Description: This site provides a concise, but thorough introduction to NMR spectroscopy with a focus on 2D NMR. This site will be most useful for students with some introductory background in NMR. The basic principles of common 2D NMR experiments are presented and illustrated with spectra. Instructors wanting to illustrate the appearance of a TOCSY, NOESY, or COSY spectrum to an undergraduate class will also find useful information on this web site.
	A Beginners Guide to Ion-Selective Electrode Measurements	Details
	Description: A relatively comprehensive presentation of the theory, types, practices, and errors associated with ion selective electrodes. Information is listed in a hyperlinked table of contents. The last section of the site includes a thorough glossary of terms.
	A Biosensor for Fullerenes and Carbon Nanotubes	Details
	Description: This site contains an article that describes the use of surface plasmon resonance (SPR) spectroscopy to monitor real-time protein binding with fullerenes and carbon nanotubes. The introductory section provides a brief description of SPR and how it works. It next talks about the features of the Texas Instrument's SPR, known as Speetra, which is a small self-contained apparatus for light measurements. It is followed by sections discussing the properties of fullerenes and carbon nanotubes, and the methods of surface binding with monoclonal antibodies. Experimental procedures are discussed followed by example results. An analysis and explanation of results in the concluding discussion section provides useful guidance to students and practitioners.
	A Glossary for Mass Spectrometry	Details
	Description: A compilation of some of the more widely used terms that non-mass spectrometrists may encounter, and for which a simple definition would be helpful. (3.5 MB PDF file)
	A Pictorial Representation of Product Operator Formalism: Non-Classical Vector Diagrams for Multidimensional NMR	Details
	Description: This site presents a pictorial description of the product operator formalism using a non-classical vector approach. This approach allows for the representation of any arbitrary multidimensional or heteronuclear NMR experiment. A description of a complete set of 16 vector representations for weakly-coupled two-spin (I=1/2) systems is given followed by an extension of this set to three-spin systems. Finally the concepts of coherence transfer, multiple quantum spectroscopy and phase cycling are illustrated using 2D COSY, 2D INADEQUATE, DEPT and sensitivity-enhanced HSQC as examples. The content is geared to those that have some background in NMR spectroscopy, and is probably most appropriate for a graduate course in NMR. As this non-classical vector representation is used to pictorially depict product operators a basic understanding of product operators would serve the reader well. The text is well written and referenced. The figures being the heart of the manuscript are very well done and easy to follow with concise figure captions. The examples are well chosen and show how easily sequences can be described with this approach. In the case of the sensitivity-enhanced HSQC it is particularly effective in showing how the unobservable magnetization at the end of a normal HSQC is converted to observable magnetization by the additional pulses and thus generating the enhancement. This site can be used as a teaching tool as well as by practitioners who would like to easily deconstruct a pulse sequence for a better understanding of the �spin engineering� involved.
	A Primer on Scanning Tunneling Microscopy (STM)	Details
	Description: A video primer on STM by Prof. R. Reifenberger, Purdue University Nanotech Center. A thorough discussion of fundamentals followed by the technical barriers and implementations - excellent graphics illustrating principles and experimental results. Historical context is provided making presentation interesting. Should be viewed by anyone interested in surface analysis at atomic dimensions.
	Accelerator Mass Spectrometry in Biology and Health Care	Details
	Description: This video, developed at Lawrence Livermore National Laboratory, describes the instrumentation for accelerator mass spectrometry and its applications. The video describes the instrumentation and its application for carbon dating and measurements of drug distribution.
	Accuracy and Resolution	Details
	Description: This is a one-page site focused on mass accuracy and resolution.
	Adsorption and Chromatography in Bioseparations	Details
	Description: This material was developed for a final year undergraduate bioseparations module. There are a number of links to sites for modeling adsorption chromatography. For example, a link to an Excel spreadsheet provides a demonstration of varying N, l, and K (or alpha)affect band separation. Other links explain adsorption isotherms in the context of bioseparations.
	Advanced Chemistry Development	Details
	Description: This site contains slides to accompany lectures in HPLC. They do not contain enough description for the average student to follow. However, they provide a lot of excellent information about practical aspects of HPLC that faculty could find useful for their own lectures on the topic. The sections on troubleshooting, sample preparation, gradients, system peaks, system suitability and methods validation are particularily valuable. The illustrations and diagrams are informative but occasionally difficult to read because of their resolution. Applications and examples are very good. This is a subset of Dr. Levin's more extensive page regarding chromatography, but a link to that home page is provided.
	Affinity Chromatography	Details
	Description: This is an experiment showing the application of affinity chromatography to the separation of albumin from horse serum. A brief introduction of affinity chromatography and how it is being used in this specific experiment is given. This appears to be a good experiment to show the advantages of affinity chromatography in separating specific proteins from a complex matrix and would be useful in a biochemistry course or a course that is specifically looking at differing types of chromatography.
	Affinity Chromatography	Details
	Description: Using exposition, graphics, and commercial videos, this module teaches the theory and application of affinity chromatography in the characterization of proteins, nucleic acids, and other biochemical/biomedical systems. Problems and application examples support the tutorial material.
	AJP Martin Nobel Prize Address	Details
	Description: This site describes the historical development of partition chromatography. The pedagogical value lies in its historical perspective rather than its description of partition chromatography. This site provided a unique historical perspective on the development of partition chromatography and one of the pioneers of the technique.
	All about Electrochemistry	Details
	Description: Site contains introductory material in basic electrochemistry. Topics include galvanic cells, electrodes, cell potentials and thermodynamics, Nernst, batteries and fuel cells.
	All about light -- diffraction, reflection, gratings, animations	Details
	Description: This is a very detailed site about the physics of electromagnetic waves including diffraction and interference. The site has several components. A large list of animations is provided, but several of the links are no longer active, so this feature is less useful than it could be. The site also has a series of lecture notes, as pdfs, and nice slides that describe various aspects of the behavior of electromagnetic radiation. This site may be useful for instructors teaching spectroscopy. Students may need some advice about where to go and what to do.
	An Eye on Food	Details
	Description: This C and E News cover story from July 2005 introduces readers to the concept of quality control in food analysis for food safety with an emphasis on the application of near-infrared (NIR) and encoded photometric infrared (EP-IR) spectroscopy, fourier transform ion cyclotron resonance mass spectrometry (FT ICR MS), and microchip analysis. This article would be of potential use to faculty teaching any of these topics in their classroom.
	An Inexpensive Field-Programmable Potentiostat	Details
	Description: This website describes the practical design and construction of a small, inexpensive programmable potentiostat including a list of the components and circuitry for building a complete self-contained potentiostat - all for approximately $50 in component cost. Explanation is given about the basics and the operational characteristics of this potentiostat, illustrated by running cyclic voltammetric scans of potassium ferricyanide in a 3-electrode cell. The noise, as seen by the small oscillations on the voltammograms, may be lessened by the use of a shielded/grounded case with use of BNC connectors for attaching the electrodes to the potentiostat. Some of the components may no longer be manufactured and may have to substituted with equivalent available parts. Students interested in analytical instrumentation or electrochemistry, including projects involving field-portable electrochemical instrumentation, might also find this potentiostat useful. This is a good example of a practical instrument/ circuit design.
	An Introduction to Surface Chemistry	Details
	Description: Theoretical and descriptive material for an introductory surface science course. Topics covered include structure of surfaces and detailed information on a variety of surface analytical techniques, essentially an online text.
	An Unusual Arson Case: Polymer Grains	Details
	Description: A case example of determination of an arson accelerant by a variety of analytical techniques. Will make a good case record for an active learning class. Uses a variety of techniques, particularly chromatography and headspace analysis.
	Analytical Electrochemistry: Basic concepts	Details
	Description: This module focuses on dynamic electrochemistry, that is, the combination of mass transfer and electrochemical reaction typical of redox reactions at the interface between solids and fluids when current is not zero. It is an introduction at a level appropriate for undergraduates in their sophomore or junior years.
	Analytical Electrochemistry: Potentiometry	Details
	Description: This courseware module is structured for either a lecture presentation or self-study tutorial on analytical potentiometry. The level of presentation spans upper high school to college students. Topics include historical background, theory/principles, instrumentation, pH electrodes, experimental examples, and troubleshooting tips.
	Analytical Instruments and Spectroscopic Concepts	Details
	Description: Primers for different analytical techniques (HTML, PDF). Also links to animations and audio descriptions of analytically related concepts. Techniques include atomic absorption, spectrophotometry, chemiluminescence, gas chromatography, mass spectrometry, and atomic emission.
	Animated Infra-Red Spectroscopy (AIRS)	Details
	Description: Interactive animations of infrared spectroscopy absorptions for small organic compounds. Click on an absorption in the IR spectrum to see which atoms vibrate in the molecular structure. QuickTime software is required to view animations. Most useful as a teaching tool for introductory courses.
	Animated Webpage Explaining STM	Details
	Description: This is an animated gif that illustrates how scanning tunneling microscopy (STM) works. As such it is valuable to students and faculty interested in learning about this important surface analysis technique.
	Animation of diode array detection in HPLC	Details
	Description: This site is one in a series of sites with very good animations related to separations. This animation deals specifically with diode array detection for liquid chromatography. The animations are short (one to two minutes) and can easily be shown in class as part of a lecture. They are extremely helpful in illustrating key components and concepts of chromatographic systems. Users are encouraged to explore the site and the other brief animations as well. Separate links to other simulations by the same company (TRSL) are also listed on ASDL. This site requires FLASH version 7 or higher in order to work properly
	Animation of Dual Head HPLC Pump	Details
	Description: This site is one in a series of sites with very good animations related to separations. This animation deals specifically with dual head LC pumping. The animations are short (one to two minutes) and can easily be shown in class as part of a lecture. They are extremely helpful in illustrating key components and concepts of chromatographic systems. Users are encouraged to explore the site and the other brief animations as well. Separate links to other simulations by the same company (TRSL) are listed below.
	Animation of GC flame ionization detector	Details
	Description: This site is one in a series of sites with very good animations related to separations. This animation deals specifically with flame ionization detection in GC. The animations are short (one to two minutes) and can easily be shown in class as part of a lecture. They are extremely helpful in illustrating key components and concepts of chromatographic systems. Users are encouraged to explore the site and the other brief animations as well. Separate links to other simulations by the same company (TRSL) are also listed on ASDL.
	Animation of GC solvent focusing	Details
	Description: This site is one in a series of sites with very good animations related to separations. This animation deals specifically with solvent focusing in gas chromatography. The animations are short (one to two minutes) and can easily be shown in class as part of a lecture. They are extremely helpful in illustrating key components and concepts of chromatographic systems. Users are encouraged to explore the site and the other brief animations as well. Separate links to other simulations by the same company (TRSL) are listed below.
	Animation of pulse dampner in HPLC	Details
	Description: This site is one in a series of sites with very good animations related to separations. This animation deals specifically with pulse dampners is LC and could help in a general lecture about LC pumps. The animations are short (one to two minutes) and can easily be shown in class as part of a lecture. They are extremely helpful in illustrating key components and concepts of chromatographic systems. Users are encouraged to explore the site and the other brief animations as well. Separate links to other simulations by the same company (TRSL) are also listed on ASDL.
	Animation of Quadrupole GC-MS detection	Details
	Description: This site is one in a series of sites with very good animations related to separations. This animation deals specifically with quadrupole mass spectrometry detection for chromatography. The animations are short (one to two minutes) and can easily be shown in class as part of a lecture. They are extremely helpful in illustrating key components and concepts of chromatographic systems. Users are encouraged to explore the site and the other brief animations as well. Separate links to other simulations by the same company (TRSL) are listed below.
	Animation of sample loop HPLC injections	Details
	Description: This site is one in a series of sites with very good animations related to separations. This animation deals specifically with sample loop injections in liquid chromatography. The animations are short (one to two minutes) and can easily be shown in class as part of a lecture. They are extremely helpful in illustrating key components and concepts of chromatographic systems. Users are encouraged to explore the site and the other brief animations as well. Separate links to other simulations by the same company (TRSL) are listed below.
	Animation of single wavelength UV-vis detection for HPLC	Details
	Description: This site is one in a series of sites with very good animations related to separations. This animation deals specifically with single wavelength UV-vis detection for liquid chromatography. The animations are short (one to two minutes) and can easily be shown in class as part of a lecture. They are extremely helpful in illustrating key components and concepts of chromatographic systems. Users are encouraged to explore the site and the other brief animations as well. Separate links to other simulations by the same company (TRSL) are also listed on ASDL.
	Anodic Stripping Voltammetry	Details
	Description: Site provides basics with illustrations of what happens during deposition and stripping of metals for analysis by anodic stripping voltammetry (ASV). The PDF presentation is easy to navigate and understand. It can be used as a supplement to a lecture or lab.
	Application Notes From LECO	Details
	Description: Application notes and experimental protocols for a variety of inorganic and organic analytes. Topics covered include analysis of food and beverage samples, natural products, pharmaceuticals, environmental contaminants and industrial applications. The main techniques described are near infrared spectroscopy, liquid and gas chromatography, time-of-flight mass spectrometry and glow discharge optical spectroscopy.
	Applications Searchable Site	Details
	Description: This site is a search engine for chromatographic and mass spectral methods in the Waters Corporation database. It searches based on analyte. It pulls up refereed journals(citations only) and company literature (pdf format). The site claims 23,500 documents. The site will be useful to those looking for methods in chromatography, including faculty and students looking for project ideas for either research or laboratory experiments.
	Atomic Absorption Instruction Module	Details
	Description: An introduction to Atomic Absorption Spectroscopy for the non-chemist or new user.
	Atomic Emission Spectroscopy	Details
	Description: Directed to students in Instrumental Analysis or practitioners without convenient access to a class in Instrumental Analysis, this module explains the instrumental systems and interactions involved in atomic emission for elemental analysis. Completion of the module will leave the learner with knowledge of optics, plasma sources, and trade-offs in choosing the right instrument for a given analytical task.
	Atomic Force Microscopes � Tutorial Page	Details
	Description: This site prepared by Pacific Nanotechnology, Inc. provides a basic tutorial on the basic principles of atomic force microscopy (afm), the fundamental modes of operation, and the basic instrumentation that should be accessible to interested undergraduate analytical chemistry students as well as analytical chemistry instructors. The information is available both in html and downloadable pdf format.
	Atomic Force Microscopy	Details
	Description: A video lecture on Atomic Force Microscopy (AFM) by Prof. Arvind Raman of Purdue University that discusses the historical development, instrumentation and operational principles of various AFM modes. The lecture is accompanied by power point slides with clear illustrative graphics. Basics are provided in the application examples with advantages and limitation discussed. Useful site to those interested in learning AFM.
	Atomic Structure and the Periodic Chart	Details
	Description: This online eText consists of a thorough descriptive overview of atomic structure. The presentation is at a level suitable for high school or general chemistry students at the college level. However, the historical context of understanding atomic stucture and covderage of essential experiments and theoretical developments make this site suitable as a review primer for upper level undergraduates. The site is well organized and separated chronologically into section on quantum; light particles and waves; the Bohr atom; the quantum atom; atomic electron configuration (Aufbau); and periodic properties. It contains hyperlinks to interactive demonstration of physiochemical principals with questions posed. At the end of each section, flowcharts, called "concept maps" guide the students from basic principles to working concepts.
	Basic Concepts of Optical Microscopy	Details
	Description: A comprehensive primer on the basic optical microscope, as well as the electron, confocal, polarizing, and stereoscopic microscopes. Virtual microscopes allow the user to simulate the use of a variety of real-life microscopes. There are galleries of photomicrographs illustrating a variety of specimens. This website provides complete instructional materials on the theory of light and the applications of microscopy to a variety of analytical problems.
	Basic Liquid Chromatography	Details
	Description: A complete textbook of liquid chromatography by Yuri Kazakevich and Harold McNair on the Web. Extraordinarily comprehensive in its coverage of fundamental chromatographic theory and instrumentation for a website.
	Basic Microscopy Concepts	Details
	Description: The site provides introductory information related to optical microscopy. Among the topics addressed are resolution, numerical aperture, depth of field, field of view, illumination and the useful magnification range. A section on fluorescence microscopy is also included. Interactive video is used to demonstrate concepts in some cases. Researchers and educators interested in a brief overview of optical microscope principles may find the site useful.
	Basics of NMR	Details
	Description: An online text on the basics of Nuclear Magnetic Resonance (NMR) spectroscopy. The text contains information especially appropriate for the novice, but topics are treated at sufficient depth to be useful for more advanced students. This resource features animations that illustrate complex NMR concepts such as precession and the rotating frame of reference.
	Biosensors and Other Medical and Environmental Probes	Details
	Description: This site links an article from the Oak Ridge Nat'l Laboratory that reviews publications dealing with biosensors and their applications. Although limited to work from ORNL's scientists, it contains several examples of cutting-edge sensor devices with sufficient background information linking their use to real-world applications. The narative is written more in a story-telling fashion than as a journal report that contributes to its readability. The descriptions and graphic illustrations contribute to the understanding of how these biosensors function. Article provies a good overview of new medical sensing technology - a resource for instructors wishing to provide an overview of different types of biosensors and their applications.
	Bragg's Law and Diffraction	Details
	Description: This site presents an introduction to Bragg's Law of Diffraction, along with how diffraction of x-rays provides information on atoms in crystalline material. An Applet allows the user to vary the wavelength and angle of incidence of radiation to a surface, along with the distance between layers of the material to demonstrate the conditions necessary for constructive interference, or a Bragg's condition. The derivation of Bragg�s law is also explained.
	Capillary electrophoresis movie	Details
	Description: This website is an animation describing aspects of CE separations, including electroosmotic flow, the separation, injection (hydrodynamic and electrophoretic) and detection (direct and indirect).
	Capillary Electrophoresis Primer	Details
	Description: This site presents a primer on capillary electrophoresis. This is a very complete treatment covering the basic theory of CE, sample stacking techniques, and practical information about optimizing CE separations. There is an animation showing how to properly cut a capillary and a glossary of terms for analytical validation. The site provides theory and background to CE but perhaps not as in as much depth as an introductory instrumentation text. On the other hand it has a large range of practical tips that a student would not necessarily get from a text. The link to "Helpful Hints for Improved Capillary Electrophoresis" which includes a section on selection of buffers, tables of buffer pKa's, buffer additives, conditioning capillaries and troubleshooting problems.
	Capillary electrophoresis: a versatile family of analytical techniques	Details
	Description: This site contains a review article covering capillary electrophoresis and variations thereof. The material presented is largely similar to that which can be cfound in textooks or primers, but this is in a nice condensed version. As the author states, the article "reviews basic principles behind the technique and the range of options which allow the same instrument to be used for the separation and analysis of a wide range of analytes from large biomolecules, such as proteins and nucleic acids, to metal and organic ions while having the capability to resolve enantiomers and non-charged molecules."
	CASE TEACHING NOTES for Filthy Lucre	Details
	Description: The website presents a case study involving the detection of cocaine on dollar bills. The case study uses GC-MS, but has an introduction appropriate for beginning chemistry students.
	Cell Phone Spectrophotometer	Details
	Description: Instructions and software are provided to allow students to build an inexpensive spectrophotometer, using digital cameras or cell phone cameras as array detectors. Supplementary materials include instructions for high school teachers and laboratory instructions for both high school and college students. Software source code allows customization.
	Chem 212 - Separations Science	Details
	Description: Superb website providing instructional materials in support of a problem-based learning approach to Quantitative Analysis (equilibria and separations). Materials available include textbook chapters, in-class, and out-of-class problems, a peer/peer evaluation tool, and a handout in support of a final course lab project report. The majority of materials are provided in an Adobe pdf format - very helpful for adoption by interested faculties.
	CHEM 525 NMR Spectroscopy	Details
	Description: This site provides both classical and quantum mechanical descriptions of NMR. Some nuts and bolts aspects of NMR and the basics of two-dimensional spectroscopy are also covered. This web site should be informative for graduate students or professionals seeking a more thorough understanding of the basic principles underlying NMR spectroscopy.
	Chemical Separations	Details
	Description: This site contains complete notes in a PowerPoint-like presentation for a chemical separations course. It covers a wide variety of topics, including distillation, extraction, gas chromatography, liquid chromatograpy, chromatography theory, instrumentation, electrophoresis, field flow fractionation, and affinity chromatography. It covers these topics thoroughly using a clear, consistent, and simple presentation style. Links to major topics like GC, LC, and electrophoresis provide specific information about the theory, instrumentation, and practice related to these techniques. Many students will find this, and its companion sites, quite helpful.
	Chemiluminescence for Chromatography	Details
	Description: This site is a brief description of chemiluminescence detection for chromatography.
	Chemistry-Based QuickTime Movies, Animations, and Streaming Audio	Details
	Description: Downloadable animations and movies for analytical instruments and processes. Formats in QuickTime, GIF animations, and Flash animations.
	Chrom. and Electrophoresis experiments with PDFs	Details
	Description: A site with PDF links to several slab gel electrophoresis, HPLC, and GC experiments intended for high school or college audiences. This site may provide a useful starting point for faculty seeking to implement new laboratory experiments based on these techniques. A login (email address) is required, but once logged in, follow the "Free Resources" link to see many instrumental and analytical experiments that have been submitted to the site.
	Chromatography	Details
	Description: An introductory site about chromatography that does not go into great depth. However, the simulation of paper chromatography is worth exploring with students as it illustrates that the separation of compounds relies on the difference in the solutes affinities for the mobile phase relative to the stationary phase. Because of its apparent simplicity, this simulation has significant pedagogical potential and could be used in a variety of ways in class to explore the factors governing chromatographic separations.
	Chromatography	Details
	Description: Multiple links in a broad discussion of several facets of chromatography - including theoretical and instrumental aspects. Five modes of chromatography are highlighted: GC, HPLC, LC, SEC and TLC.
	Chromatography	Details
	Description: This site provides fundamental background information about chromatogaphy, including plate theory, rate theory, the meachanisms of separations, and qualitative and quantitative aspects of chromatography. The format is a PowerPoint-like presentation. It is a subsite of a larger, broader site about chemical separations (http://ull.chemistry.uakron.edu/chemsep/index.html). The combination of all of the related sites is quite nice and students will find them useful.
	Chromatography and Mass Spec Lectures	Details
	Description: This site contains mass spectrometry and chromatography lecture notes for a graduate course. They are subdivided by topic (history, theory, etc.) and are easy to browse. They may be helpful to someone constructing their own course in chromatography and/or mass spectrometry. The notes are fairly complete. The historical sections may particularly save time in preparing courses. The notes also provide good information and a helpful outline to follow. The site also has some nice mass spectrometry animations from Thermo.
	Chromatography books	Details
	Description: This site simply offers books covering a wide range of both general and specific topics related to gas chromatography and its applications. While not of immediate pedagogical value, it may be useful to those looking for good texts about gas chromatography either for their own research needs or to provide as resources to their students.
	Chromatography Nomenclature and Definitions	Details
	Description: This website gives the IUPAC approved definitions in the field of chromatography. It is critical for students to appreciate the importance of using standardized nomenclature and definitions.
	Chromatography Theory	Details
	Description: This site contains standard definitions related to chromatgraphy similar to treatments found in analytical textbooks. It introduces the beginning student to LC concepts relevant to biochemistry and includes a good example of choosing a mobile phase pH for a protein separation based on ion exchange.
	Chromatography Theory	Details
	Description: James Hardy has produced a number of powerpoint type lecture modules for analytical chemistry. This is another very good module that covers the introductory theory of chromatography. Includes chromatography types, plate and kinetic theories. Level of presentation is at the introductory analytical chemistry level. It is a colorful and well planned presentation of the introduction to chromatography that could be used as the basis for lectures on chromatography at the introductory analytical chemistry or instrumental analysis level.
	Chromatography theory and modes	Details
	Description: This site is an introductory lecture in outline form about chromatography. It appears directed toward biochemical separations. The coverage is broad but not deep. Discussions of counter-current separations, gel permeation, and ion exchange are accompanied by some mention of partition, paper, and gas chromatography
	Coal Sampling	Details
	Description: This USGS method explains the use of fluxes for preparation of coal for elemental analysis. Useful to supplement textbooks concerning sample preparation and may be useful in designing an XRF laboratory experiment.
	Concepts, Instrumentation and Techniques in Atomic Absorption Spectrophotometry	Details
	Description: This pdf file contains a well written and thorough introduction to atomic absorption suitable for use by undergraduates and faculty teaching instrumental analysis courses. Topics covered in the document include theoretical concepts and definitions, flame atomic absorption, instrumentation, analytical interferences, sampling techniques, graphite furnace atomic absorption, and plasma techniques.
	Craig countercurrent extraction machine applet	Details
	Description: This site provides a useful applet that demonstrates countercurrent extraction. The explanation of the method is short, but good. The level is appropriate for undergraduate students. The Applet itself is well designed and provides a useful exercise for students around which homework or small-group waork could be developed. The use of color is particularly helpful. The same author has a larger collection of applets about instrumentation and other analytical concepts in the ASDL collection. It can be found by searching the ASDL library using 'applets' as the keypword, or going to the site: http://www.chem.uoa.gr/applets/Applet_Index2.htm
	Custom Designed HPLC Couse for Teva Abic	Details
	Description: This site contains slides to accompany lectures in HPLC. They do not contain enough description for the average student to follow. However, they provide a lot of excellent information about practical aspects of HPLC. The sections on troubleshooting, sample preparation, gradients, system peaks, system suitability and methods validation are particularily valuable. The illustrations and diagrams are informative but occasionally difficult to read because of their resolution. Applications and examples are very good. This site is a subset of Dr. Levin's larger site related to teaching separations and other analytical topics, but a link to her home page is provided.
	Cyclic Voltammetry	Details
	Description: This site describes a cyclic voltammetry experiment at a Au electrode to determine the electrode capacitance (in the presence and absence of octadecane thiol), the formal potential and diffusion coefficient of ferricyanide, and the CV irreversibility with Co(NH3)6+3. A tutorial-like discussion of the above subjects is presented. Experimental procedure can be readily implemented in courses such as instrumental analysis
	Cyclic Voltammetry	Details
	Description: This site provides an excellent experiment involving cyclic voltammetry at a gold electrode. The experiment includes a detailed introduction to the topics of electrode capacitance, electrode reactions, and flux of the electroactive species to electrode surface. Lab report guidelines and post-lab questions are included.
	Cyclic Voltammetry Simulator	Details
	Description: This simulator allows the modeling of responses from experiments in cyclic voltammetry, and is applicable to a wide variety of parameters. Excellent instructional aids in text form include description of electrochemical reversibility, diffusion, instrumentation and interpretation of cyclic voltammograms, with real-time demonstration of parameter changes.
	Detecting subsecond dopamine release with fast-scan cyclic voltammetry in vivo	Details
	Description: This article from Clinical Chemistry describing the technique of fast-scan cyclic voltammetry (FSCV, > 100 V/s) applied in vivo for the detection of dopamine release and uptake. It is a good follow-up to an earlier paper by Stamford and Justice that is also in asdlib.
	Detection of Arson accelerants	Details
	Description: Analysis of arson with detailed information on quality control and methods of transfer, excellent sample chromatograms. Could be used as a problem based learning tool. Illustrates important aspects of headspace analysis
	Determination of DNA Bases Chemistry: A Discovery-Based Experiment	Details
	Description: The paper contains details of an electrochemistry lab where students are given the time to explore and design an experiment to identify the different DNA bases. The paper has a very useful compendium of literature relating to electrochemical techniques.
	Dip Pen Nanolithography	Details
	Description: This website provides a clear, succinct introduction with good quality graphics to the technique of dip pen nanolithography. The site also provides numerous references on the technique from the Mirkin lab (Northwestern) to the technique.
	Educator's Reference Guide for Electrochemistry	Details
	Description: This website contains a substantive discussion on the basics of voltammetry accompanied by description of cells, electrodes and example experiments from use of cyclic voltammetry and to comparison between chronoamperometry, chronopotentiometry and cyclic voltammetry. The discussion of the basics is not aimed for commercial purposes although the experiments do employ examples from use of Pine Instrument potentiostats.
	Electro-Optics Handbook	Details
	Description: The Electro-Optics handbook is a 14 chapter reference text which addresses sources of radiation including lasers, detection and detectors, photometric quantities, and geometric optics. Specific detail can be found with the extensive appendix. The text is technical and lists equations without derivations.
	Electrochemical Detection of Phenol Utilizing a Synthesized Sonogel-carbon Zirconium Oxide	Details
	Description: This experiment is designed for senior undergraduate students in an inorganic chemistry course. Students are asked to synthesize a sonogel-carbon electrode that is modified with a ZrO2 sol-gel and to compare the results to those of an unmodified electrode for the detection of phenol.
	Electrochemical Education	Details
	Description: The purpose of this site is to collect in one location resources useful to educators attempting to incorporate modern electrochemical techniques into the undergraduate chemistry curriculum.” Contains links to material on experiments, equipment, proposal writing, etc.
	Electrochemical Listing	Details
	Description: Listing contains titles and links to over 40 sites, like journal articles, course and tutorial material, simulations, batteries, corrosion and other resources.
	Electrochemistry and Detection of Organic and Biological Molecules such as Catechols	Details
	Description: This ASDL online article describes a lab experiment whereby students learn how to prepare a conducting thin-film polymer electrode for the analysis of catechol and the effect of ascorbic acid on the cyclic voltammetric results.
	Electrochemistry Resources	Details
	Description: This is a general interest website in electrochemistry, offering answers to many common questions. Sections include impedance spectroscopy, quartz crystal microbalance, reference electrodes, simulation voltammetry, potentiostats and handling of mercury. A list of web and book references is available, as is a "contact us" tab for questions to the author.
	Electromagnetic waves and circular dichroism:an animated tutorial	Details
	Description: This website provides a tutorial on electromagnetic waves using animated graphics. The tutorial gives the student the ability to visualize, plane, and circularly polarized waves, the superposition of various types of polarized waves, and the change that results when the EM waves interact with matter.
	Electronics - Tutorial	Details
	Description: An encyclopedic collection of descriptions of electronics circuitry and principles to introduce or reacquaint readers with a wide variety of concepts. The site is very well organized to access the information needed. In addition to passive and active components, electricity and magnetism are also described.
	ELISA Animated Virtual Laboratory	Details
	Description: This animated virtual laboratory, produced by HHMI, that addresses concepts related to analytical immunoassay including the basis of humoral immunity,the foundation of ELISA, potential errors in conducting an ELISA and the sensitivity and specificity of a diagnostic test. This site has several layers including a laboratory notebook that provides experimental protocols for each step. This animation requires Shockwave to view, which is available as a free download.
	Encyclopedia of Analytical Instrumentation	Details
	Description: Site contains a comprehensive introduction to a large number of analytical instruments, their components and techniques. Example topics: basic concepts/methods, data acquisition and electronics, data handling, electrochemistry, imaging, material and surface analysis, sensors, spectroscopy, etc.
	Encylcopedia of Laser Physics and Technology	Details
	Description: This is a comprehensive encyclopedia that provides a brief definition or explanation of a keyword term or principle of laser physics and technology. The site is organized so that one can click on an alphabet letter to get a listing of keywords or terms for searching. This site will be useful for novices in the field and anyone who needs a refresher or reminder of terms and definitions. Most useful to upper division undergrads, graduate students and practitioners who need to learn terms to navigate the field of laser optics.
	EPR Basics and Application to Biology	Details
	Description: This site contains a set of powerpoint slides that discusses the basic principles underlying electron paramagnetic resonance (EPR). The slides also present examples of the application of EPR to biological systems including organic radicals in proteins, paramagnetic metal centers and spin labels.
	Everything You Ever Wanted to Know about Nanoindentation	Details
	Description: The Nanoindentation Website, Hosted By Baker's Group At Cornell, provides an introduction with illustrations to nanoindentation, the underlying mechanism, and applications. The Website is well laid out and easy to navigate. A novel feature of this website is an electronic forum that allows registered users of the site to ask questions about the technique. The site is likely to be useful to students studying materials science, nanotechnology, and surface science.
	Exclusion Chromatography	Details
	Description: This site contains a brief description of the separation mechanism in size exclusion chromatography. The picture helps visualize the separation, but is a simplified and idealized presentation. A companion site, http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/A/AffinityChrom.html, describes affinity chromatography. The two sites together may be helpful in a biochemistry course where such techniques are used or discussed.
	Experimental and Teaching Modules	Details
	Description: This site contains a set of experimental and teaching modules written by members of the European Advanced Light Microscopy Network (EAMNET). The modules are a mix of pdfs and websites that cover the fundamentals, history and practice of microscopy. The modules on microscopy, FRET, FRAP and Quantitative Multidimensional Microscopy will be of interest to chemists and biologists. Several of the modules include great graphics that would be helpful additions for instrumental analysis lectures.
	Experiments in Electroanalytical Chemistry	Details
	Description: This website offers educators a set of eight classical electroanalytical experiments suitable for use in a quantitative analysis, instrumental analysis, or electrochemistry course. The materials should be useful for advanced undergraduates and beginning graduate students. Experiments include coulometric, conductometric, and potentiometric titrations, stripping analysis, flow injection analysis, and polarography. It is important to note that several of the experiments use mercury or mercury coated electrodes which present safety concerns.
	Experiments in Electrochemistry	Details
	Description: This site is suitable for junior high and high school students. The website is clear and easy to use and develops the concepts in a clear and logical fashion, illustrating how Galvanic/Daniell cells work.
	Fast Scan Voltammetry	Details
	Description: A short presentation of theory and practice of electrochemistry focused on use of microelectrodes and micro-bands in flow cells. Problems encountered are addressed and response characteristics discussed.
	Flame Atomic Absorption	Details
	Description: In addition to being an introductory tutorial on Atomic Absorption Spectroscopy, the parent site has links to a variety of materials on environmental analysis.
	Flow Injection Analysis	Details
	Description: This website by Monash University provides a primer for those who are beginners as well as those who wish to have a refresher on the principles and illustrative applications of flow injection analysis (FIA). The left hand menu allows selection of topics: FIA, Princples, Dispersion Process, Modes of Applications, Recent Developments, Bibliography and People in FIA. Schematics and illustrative signal outputs are provided for each FIa method. The site is easy to browse with links to subtopics. The site is unique in terms of bringing together in one place the basics of FIA with illustrations.
	Flow Injection Analysis in the Undergraduate Laboratory	Details
	Description: This paper titled, Flow Injection Analysis in the Undergraduate Laboratory, by Rocha and Nobrega was published in the Chemical Educator. It describes two basic experiments. One is the measurement of copper using PAR reagent as carrier in a single line FIA system. Increasing the reaction coil length results in double peaks. Refractive index effects are demonstrated in the two-line system by adding ethanol. The second experiment is the measurement of phosphate with the molybdenum blue reaction in a three-line system. The effect of temperture is demonstrated, showing also the formation of bubbles at higher temperatures. The experiments are designed for a 4-hour laboratory. Unfortunately, the supplmentary PDF, which contains the schematic for the sliding-bar injector, is only available for Chem. Educator subscribers (or possibly by contacting the authors). This is a useful lab experiment for undergraduate quantitative analysis or instrumental course.
	Fluorescence Correlation Spectroscopy	Details
	Description: The is material was previously published in as part of an online biophysics textbook. Although a date for publication is not provided, it must be before cell phones were widely used based upon the following: "Imagine trying to find out if a friend had left an overcrowded shopping center without a call to the info desk. Unless you are holding hands, this is next to impossible." With the exception of this funny piece of dated material, the scientific content of the article is rich and fairly complete. It begins with a nice history of FCS from Magde to Rigler and others. It outlines the instrumentation needed including very important information that is often left out of other reviews: the number of filters needed to block IR and back filling the objective. There are other nice details in the article: a discussion of 2 channel excitation in confocal microscopy, photobleaching in the focal volume only in two-photon microscopy, and how one can tune the two-photon laser for multi-color excitation. There is also a nice detail of the theory and math involved in autocorrelation and cross-correlation detection. The authors discuss the observables FCS can detect: number of molecules in the focal volume, brightness (aggregation), diffusion times, and the ability to differentiate between diffusion, active transport, anonomolous diffusion or convection. Overall, a very strong review of FCS for the first time FCS student, or as a refresher. It could be used for teaching notes to teach FCS in a course. Nice graphics as well.
	Fluorescence Detection Animation	Details
	Description: This site is one in a series of sites with very good animations related to separations. This animation deals specifically with fluorescence detection for liquid chromatography. The animations are short (one to two minutes) and can easily be shown in class as part of a lecture. They are extremely helpful in illustrating key components and concepts of chromatographic systems. Users are encouraged to explore the site and the other brief animations as well. Separate links to other simulations by the same company (TRSL) are also listed on ASDL.
	Fluorescence Polarization Assays	Details
	Description: This website describes fluorescence polarization methods and how they can be used to assay ligand-protein binding. Fluorescence polarization measurements are important for a variety of bioanalytical applications including receptor-ligand, protein-protein and DNA-protein binding. This resource includes a diagram illustrating how the measurements are performed, the relevant equations, and links to several papers describing the use of this technique in in protein binding assays.
	Fluorine NMR	Details
	Description: This article describes the use of fluorine (19F) NMR for the analysis and structure determination of biomaterials. Using a traditional text-with-figures format, the article gives an overview of the synthesis of 19F spin-labeled materials and detailed descriptions of 19F chemical shifts and relaxation phenomena as applied to both primary and tertiary structure determinations of biochemical interest. The article has a lot of practical iformation. Definitely a resource that someone considering using fluorine NMR should consult. This article will be most useful to advanced students. Prerequisites for this treatment of 19F NMR include introductory courses in NMR, organic chemistry, and biochemistry.
	Fourier Transform	Details
	Description: An overview of the Fourier theorem as applied to analytical measurements is given. The Discrete Fourier Transform and the Fast Fourier Transform algorithms are mentioned, and sampling requirements are discussed. Links are provided to descriptions of Fourier transform based mass spectrometry, infrared spectroscopy and NMR techniques.
	FTIR Spectrometry	Details
	Description: The site demonstrates principles behind the operation of the interferometer in an FTIR spectrometer. Graphics and interactive movies are used. Examples start from a single wavelength and build to the superposition of multiple wavelengths. The connection between an interferogram and a frequency domain spectrum is discussed.
	Fundamentals of GC/MS	Details
	Description: This tutorial provides an excellent introduction into the fundamentals of GC/MS. The tutorial consists of five sections: An introduction of mass and types of ions, ionization modes, hardware, figures of merit describing mass analyzer performance, and qualitative methods of GC/MS analysis - including library searches. Each section contains animations or simulations of chemical and physical interactions that pertain to mass spectrometry such as gas-phase ionization processes, fragmentation, mass analyzers, the importance of a vacuum, and detectors. A basic introduction to gas-liquid chromatography is also provided. The tutorial is intended to describe GC/MS at an introductory level, but does include theory at an intermediate level, which may be included or not depending on the intended audience. Information is presented in a Powerpoint style, and each figure has a Details tab which provides additional information on the subject. This website has excellent pedagogical value for students and new practitioners.
	Fundamentals of NMR	Details
	Description: This e-text presents an introduction to the fundamentals of NMR covering magnetic resonance, pulsed NMR, relaxation, chemical shift, spin-spin coupling, the nuclear Overhauser effect and chemical exchange.
	Gas Chromatography	Details
	Description: This EPA site provides a brief overview of EPA remediation methods and projects. The links "Remediation" and "Characterization and Monitoring" have sub-links that provide analytically relevant materials. Many applications and case-specific studies are presented. Many of the links are related to sampling statistics.
	Gas Chromatography	Details
	Description: This site contains a brief introduction to the concepts of injection and detection in gas chromatography, focusing on the split/splitless injection port and flame ionization detectors. The treatment is similar to that in analytical chemistry textbooks.
	Gas Chromatography Application Notes	Details
	Description: Application notes from 2000-2005 presented at conferences (the conferences are not identified listied by year). Applications could serve as a source of experiments for advanced teaching labs and also assist those interested in solving analytical problems that involve separations.
	Gas Chromatography experiment	Details
	Description: This site provides a Word document that describes a GC experiment involving the separation and quantitation of four butyl alcohol isomers. It has a complete background about the components of a GC instrument (with labeled pictures) and their functions. It has a section devoted to the measurement of response factors of the detector in use (here an FID). This would be a good experiment for a new faculty member to use as is, with slight modification to make it relevant to the particular GC system to be used.
	Gas Chromatography Video	Details
	Description: This is a high quality video module demonstrating the basics of gas chromatography. Highlights include different GC instruments, detectors etc., as well as unique topics such as trouble shooting and interfacing the column that are not addressed in standard texts. This resource can be run (Shockwave Flash) from the home server or downloaded to your computer.
	GC books	Details
	Description: This site contains a list of books about gas chromatography with their tables of contents. Potentially useful for practictioners or research students needing an introduction to GC. Some links (such as those to spectroscopy, NMR, and LC) do not yield any useful information.
	GC coating animation	Details
	Description: This site is one in a series of sites with very good animations related to separations. This animation deals specifically with solute retention in GC. The animations are short (one to two minutes) and can easily be shown in class as part of a lecture. They are extremely helpful in illustrating key components and concepts of chromatographic systems. Users are encouraged to explore the site and the other brief animations as well. Separate links to other simulations by the same company (TRSL) are also listed on ASDL.
	GC Electron Capture Detector Animation	Details
	Description: This site is one in a series of sites with very good animations related to separations. This animation deals specifically with electron capture detectors. The animations are short (one to two minutes) and can easily be shown in class as part of a lecture. They are extremely helpful in illustrating key components and concepts of chromatographic systems. Users are encouraged to explore the site and the other brief animations as well. Separate links to other simulations by the same company (TRSL) are also listed on ASDL.
	GC Splitless Injection Animation	Details
	Description: This site is one in a series of sites with very good animations related to separations. This animation deals specifically with splitless injection in GC. The animations are short (one to two minutes) and can easily be shown in class as part of a lecture. They are extremely helpful in illustrating key components and concepts of chromatographic systems. Users are encouraged to explore the site and the other brief animations as well. Separate links to other simulations by the same company (TRSL) are also listed on ASDL.
	GC/MS with animations	Details
	Description: This site contains a good review of GC detectors that is linked to animated files describing the hardware and principles of operation for GC/MS. From this site, one can also get to multiple other animations about a variety of analytical topics.
	GlobalFIA	Details
	Description: This site by GlobalFia provides a tutorial on the general aspects of flow injection analysis (FIA), sequential injection analysis (SIA) and the newly coined zone fluidics. Thus, it serves as an excellent resource for teaching flow methods to both undergraduates and graduate students, and as a refresher to practitioners. The tutorials are divided into 9 sections: introduction, fundamentals, dispersion, enrichment, chemistry, SIA, zone fluidics and bibliography. This modular approach makes information on concepts easy to digest and builds sequentially on each previous module with accompanying illustrative graphics. The bibliography provides references to hardcopy primary sources and a link to the FIA database at U. North Florida. The step-by-step instruction for the development of a new SIA method could be very helpful to someone who may be starting a new system or wishing to develop and new experiment. The site is easy to browse.
	Guidance for Industry: Bioanalytical Method Validation	Details
	Description: This site is a pdf document for analytical scientists detailing what is necessary to make a methodology acceptable to the FDA. As such it should provide an "eye" opener to students trying to learn the analytical mindset. This site will be especially useful for instructors presenting material on method validation. It is also a valuable resource for students considering employment in the pharmaceutical industry.
	Handbook of Basic Atomic Spectroscopic Data	Details
	Description: This is a NIST (National Institute of Standards and Technology) site containing atomic spectroscopic reference data. Information can be accessed through a variety of means, such as an interactive periodic table and dropdown lists of elements organized by name or atomic number. Data available include isotope abundance, electron configuration, nuclear spin, magnetic moment, ionization energies, spectral line wavelengths and intensities, and energy level information. References are also given.
	HPLC	Details
	Description: This video, distributed on YouTube by the Royal Society of Chemistry is on the basic principles of HPLC. This video is a short primer (~5 min) which introduces the basic technique and instrumentation. The theory of HPLC is described at a very basic level. Separation theory is presented in a qualitiative fashion, and both the mechanics and applications of HPLC were generally described. The ultimate strength of this video is the general nature of the content that makes it appealing to a wide audience. The video may be most appropriate in a lower-level general education science course (i.e forensic science) or as a quick orientation video for instrumental analysis students.
	HPLC Primer	Details
	Description: Nice introduction to high performance liquid chromatography that includes information on the modes of separation, a comparison of normal vs. reversed phase separations, identification of analytical, semi-prep, and preparative scale LC and a very nice large glossary that includes definitions of terms related to chromatography.
	HPLC Tutorial 2,0 Video	Details
	Description: This high quality video resource focuses on partition chromatography. The video presents an overview of basic separation theory and discusses instrumentation and data analysis. The size of the video (62.6 MB) almost requires a high speed internet connection. The resource can be downloaded to the user's computer, which is recommended for those with slower connections.
	HPLC, LC-MS, and FTIR sites	Details
	Description: This site contains a considerable amount of information on HPLC, LC-MS, and FTIR via linked sites by the same author and some vendor sites. It may require considerbale time to follow the links to find specific information, but as a collection of sites related to HPLC and FTIR it is quite useful as a teaching resource. There are some interesting animations that might be helpful for students to understand how these instruments work.
	ICP Operations: A Guide for New ICP Users	Details
	Description: This site, written by Dr. Paul Gaines, is a handbook for ICP analysis. Topics such as matrix compatibility, quality control, spectral interferences, instrument operation (e.g. sample introduction, nebulization, etc.) make this an excellent practical yet concise manual on ICP operation. This manual is instructive not only for students and faculty interested in elemental analysis, but also for novice ICP analysts.
	ICP-MS	Details
	Description: This site provides the principles of ICP-MS from sample introduction, ionization to MS quadrapole analysis. Excellent illustrative schematics of the main process in ICP-MS and pictorials of component parts. This has photos of the detector horn; photos of the actual quadrapoles; and of the plasma which are nice. The site has animations showing the nebulization (although not really related to any physical operation) and to the quadrapole. This material would serve as an excellent reference resource by students at the upper undergraduate and beginning graduate level. The detection levels for 27 elements are listed in a table.
	Immunoassay	Details
	Description: A discussion of immunoassays in the context of testing for environmental contaminants, including a fairly detailed explanation of how immunoassays are conducted and advantages and limitations in the analysis of environmental problems. There is also a discussion of analytical concerns - interferences, limits of detection, accuracy and precision, calibrating immunoassays, etc.
	Immunoassay Animations	Details
	Description: Animations showing the detailed steps involved in 8 different immunoassays. The focus of the site is primarily on the biochemical aspects of the immunoassays, not on their analytical applications.
	Immunoassay, biosensors and other non-chromatographic methods for agrochemical analysis	Details
	Description: This site is a comprehensive 58 page book chapter in pdf format on nonchromatographic methods of analysis for agrochemical contaminants (residues). The process of preparing and testing immunoassay tests is also discussed. Both biological and physical-based methods are discussed. In the former, it presents a wide variety of methods including the use of PCR. In the latter, it includes spectroscopy and voltammetry.
	Improving the Art and Practice of Amino Acid Analysis	Details
	Description: This site presents a very detailed tutorial on amino acid analysis. Topics discussed include analytical methods, calibration, hydrolysis, sample preparation, reduction of background and contamination, calculations and references. This site will be especially useful for faculty and students at all levels interested in bioanalysis and especially in the practical aspects of amino acid analysis.
	Integrated Spectral Database System for Organic Compounds	Details
	Description: Searchable database of infrared, nuclear magnetic resonance, and mass spectra of organic compounds.
	Interpreting Electrospray Mass Spectra	Details
	Description: This site is a tutorial on interpretation of electrospray mass spectra of multiply charged molecules. It provides a simple explanation of the electrospray process and the potential for the creation of multiply charged species, especially when working with peptides. The mathematics of determining the charge state and molecular weight of the peptide is also explained. Although this site provides a good foundation on electrospray MS of peptides, students requiring an advanced understanding of MS fragmentation of proteins and peptides will have to go elsewhere.
	Introduction to AFM	Details
	Description: Excellent introduction to the technique of atomic force microscopy at a level suitable for undergraduates. The page describes the basic modes (constant force, tapping, lift mode) and explains the significance of the tip and tip effects in imaging.
	Introduction to Antibodies	Details
	Description: This site contains a thorough overview of the fundamentals of antibodies. The site starts with an introdution to antigens and antibodies, antibody production and titer including practical informatio.
	Introduction to Capillary Chromatography	Details
	Description: This site discusses many of the details in how ro convert a traditional HPLC system into a capillary HPLC system. Included in the discussion is how to use splitting to get to the lower flow rates required and how to pack your own capillary LC columns. There is detailed information on how to go about plumbing these sorts of systems (use of fittings, etc.), which may be valuable to someone who doesn't have that experience. The site also includes links to purchasing the components necessary for performing this conversion. This site noes not include theory or advantages and disadvantages of capillary LC. It is more of a "how-to" guide about converting HPLC systems.
	Introduction to Capillary Electrophoresis	Details
	Description: A comprehensive overview of capillary electrophoresis and its closesly related variants. This pdf document details both theoretical and practical aspects of CE, and includes an application index and thorough bibliography. This material is appropriate for beginners or new practitioners of CE, and would be an excellent resource for instruction in instrumental techniques.
	Introduction to Mass Spectrometry	Details
	Description: An introduction to mass spectrometry, primarily an overview of ionization methods and mass analyzers with diagrams that provide visualizations of the topics discussed.
	Introduction to Mass Spectrometry	Details
	Description: This site contains an on-line text on mass spectrometry at the intermediate level. The text gives good general coverage of mass spectrometry instrumentation and applications in very readable format. It contains nice diagrams that provide a visualization of the ionization and mass selection processes. It also contains an overview of applications of mass spectrometry near the end that is different than most sites related to MS. It is especially appropriate for intermediate students.
	Introduction to Signals and Noise: eLearning Module	Details
	Description: Basic concepts of signals, noise, and extraction of data from noisy signals are presented as an e-learning module. Excel spreadsheets allow students to vary noise parameters. Basic electronics ideas relating to RC circuits support introductory information on filters
	Introduction to X-ray Diffraction (XRD)	Details
	Description: This learning module presents the fundamentals of X-ray Diffraction for characterizing molecular structure in a form useful both as lecture notes and for self-study.
	Introductory Tutorial to Mass Spectrometry	Details
	Description: An introduction to GC-MS for beginning students in analytical or organic chemistry lab. The site includes discussion of quadrupole mass analyzers, ionization, detection, and interpretation of mass spectra. One of the best features of this site is a series of on-line quizzes on the interpretation of EI mass spectra that includes hints as well as explanations of why the answers are right or wrong.
	Ion Exchange Chromatography	Details
	Description: This website contains aN ion chromatography simulator that can be run on-line or can be downloaded. The simulator focuses on separations of Proteins using Ion Chromatography. Also included is hyperlinked reference information, an example of a homework assignment using the simulator, and some information on protein structures.(note this is an archived version of this site, as the original has been moved).
	IonSource	Details
	Description: This website contains a wealth of information about mass spectrometry for bioanalysis and related subject material for biotechnology. There are four significant components: The Card Index, Featured IonSource Tutorials and Contributions, Resources, and Links. The contents will serve as a learning tool for students, faculty and practitioners alike. You can take what you want, depending on your level of expertise and interest. The Card Index contains information on things like peptide mass calculator, acetylation reaction, protein glycosylation, phosphorsylation and MS lab calculation, etc., will be useful. Learners will find the tutorials helpful to learn about Principles of MS quantitation, Isotopes, Reverse Phase HPLC Basics, etc - and if you look under shareware/freeware, several free softwares available on the Internet are listed. This site contains a compendium of material that is not available in textbooks.
	IR Helper	Details
	Description: The website uses JCAMP formatted spectra, and javascript to lead the user through the analysis of IR spectra. The software asks the user a series of questions about the spectrum, and provides correction if the user answers incorrectly.There are 18 different spectra to choose from, from simple alkanes to a few fairly tricky assignments.
	Kinetic Capillary Electrophoresis(KCE): A conceptual Platform for Kinetic Homogeneous Affinity Methods	Details
	Description: Kinetic Capillary Electrophoresis is a family of methods for studying binding of biopolymers, measuring rate constants, binding constants, and in some cases providing mechanistic details. This Online Article is a presentation by the originators of this family of techniques ready for classroom or independent use.
	LabVIEW for Instrumental Analysis	Details
	Description: This site provides two useful resources for instructors and students of analytical chemistry. The first is a collection of Labview virtual instruments(VIs)for demonstrating topics such as signal-to-noise ratios, boxcar and ensemble averaging, power spectra, digital filtering, analog-to-digital conversions, and the Nyquest frequency. For users that do not have a working copy of Labview, executable versions are included that use Labview's free run-time engine (Windows only). The second set of resources is a series of tutorials for teaching students how to write their own VIs. The tutorials are well thought out and nicely build on each other.
	Landmark Instruments of Chemistry	Details
	Description: This website effectively uses animated movies combined with text explanations to describe the processes in FT-IR interferometry, TLC, GC and magnetic sector mass spec. It is effective in illustrating processes that are otherwise difficult to visualize. These materials are excellent visualization tools that can be incorporated into lectures readily.
	LC Calc (TM) Online. A handy calculator for HPLC computations.	Details
	Description: This site contains several on-line calculators for use in liquid chromatography. These include pressure unit conversion, buffer pH, and scale-up factors. Some links may be broken.
	LC/GC magazine	Details
	Description: LC/GC magazine is a very good source for relatively short articles about fundamental chromatographic issues as well as applications. The content is appropriate for both introdcutory analytical courses (e.g. quant) and for instrumental analysis courses.
	Learning to Learn: An Introduction to Capillary Electrophoresis	Details
	Description: This article describes a problem based learning approach to analytical chemistry labs using capillary electrophoresis as the instrumental method. The on-line link requires a password for The Chemical Educator to get the full article. The article also describes a lab that is an example of problem based learning. Students, playing the role of lab technicians, learn how to use the instrument in order to perform an analysis.
	Lecture Notes On Forensic Law	Details
	Description: This site offers lecture notes relating to an introductory survey course on forensic science. It is designed to provide a comprehensive understanding and analysis of technical and legal issues involving forensic techniques. The lectures, focus on traditional subjects relating to the services of crime laboratories,but also deals with allied subjects,including forensic psychiatry, forensic pathology, and social science.
	Light sources - Technical Information	Details
	Description: This is a commercial site with some detailed information included with product announcements. The discussion of light collection is an exceptional introduction to matching optical elements with maximum throughput. There are also illustrative spectra of typical sources and descriptions of laws of radiation and radiation units.
	Linear and Cyclic Voltammetry	Details
	Description: This website provides an introduction to linear sweep and cyclic voltammetry. The shape of the current-voltage curve for these techniques is explained with illustrations of the concentration profiles from the electrode surface into the solution at different stages of an electrochemical reduction.
	Liquid Chromatography Books	Details
	Description: This site provides a list of books related to liquid chromatography and its applications. While not immediately pedagogically useful, it may be useful to those seeking texts about LC for their own research interests or to provide as references to students.
	M.E. M�ller Institute for Microscopy	Details
	Description: This website is a nice primer for those who are interested in atomic-level surface imaging of biological samples with atomic force microscopy (AFM). The accompanying graphics are illustrative of what can be done and at what resolution. Note the material is a little dated (1996), but is still very useful. If one is interested in learning about biological imaging with other methods as well, it is recommended to open the home page site (http://www.mih.unibas.ch/Booklet/Booklet96/Intro/Intro.html) and read the introduction. You can chose chapters that describes techniques such as X-ray tomography, magnetic resonance imaging, confocal laser scanning microscopy, etc. as applied to biological surface imaging and manipulation.
	Macherey-Nagel Product Catalog	Details
	Description: Database with references for nearly 3000 separation applications.
	Mass Spec Primer	Details
	Description: This website developed by Waters Corporation provides a brief primer on mass spectrometry which includes information on instrumentation, a discussion of mass accuracy, resolution, and LC-MS. As such the site should be a valuable resource for both students and faculty.
	Mass Spectra of Fatty Acids	Details
	Description: This website on lipid mass spectra presents a nice overview of the topic of mass spectrometric determination of fatty acids with gas chromatography-mass spectrometry and electron impact ionization sources (including derivatization). at a level that should be accessible to undergraduate analytical students. The site is easy to navigate. The material is well written and generously referenced.
	Mass Spectrometry for Chromatographers	Details
	Description: This short course looks at mass spectrometers as detectors for gas chromatography. Includes instrumentation, spectral interpretation, data collection, worked problems, and a knowledge quiz.
	Method OIA-1677 Available Cyanide by FIA, Ligand Exchange and Amperometry	Details
	Description: This is a pdf version of an official EPA method for the analysis of cyanide. It discusses a variety of quality control procedures a wide range of controls that must be used for method maintenance and development. Within the context of teaching, this site could be viewed as unique in allowing students to work through all contingencies that must be moniitored for a measurement to be deemed valid. It defines and contains a variety of control parameters with mathematical descriptors. The chemistry for the flow injection analysis of cyanide is provided as well as a diagram of the instrumental setup. Cyanide is widely dispersed in the environment and its analysis should be of interest to students.
	Micro Separations Distance CE	Details
	Description: This site describes how to assemble an inexpensive, yet reliable capillary electrophoresis apparatus and provides experiments to demonstrate electrodynamically-driven separations. Good background material about CE theory is provided.
	Micro- and Nano Technology, 1st Int'l Symp 2004	Details
	Description: This site offers concise and readable description of three new biosensing technologies that are absent from textbooks. The technologies developed at Oak Ridge National Laboratory include: 1) use of nanoprobes based on plasmon-resonance (which is defined) to enhance surface Raman scattering and fluorescence; 2) an optical neurosensor based on a 40 nm fiber optical tip; and 3) a multifunctional biochip capable of DNA and other protein-based bioassays. The article is written in PDF format with several illustrative graphics. Although insufficient in details to duplicate experimentally, the article does provide a nice overview of how development of small-scale analytical measurements can be used to address important biological problems. This 6 page article is a paper that was presented at the 1st Int'l Symposium on Micro and Nano Technology in 2004. A list of references appear at the end.
	Micromechnical Biosensors and their Integration with Aptamer-based Receptor Molecules	Details
	Description: This site is one of many on "nanoHUB.org" which highlights availability of on-line simulations. This particular one provides a video of a research seminar on the topic of micromechanical biosensors focusing on aptamer-based receptor molecules. The quality of the graphics in the video is not high - mainly, the smallness of the visuals makes it difficult to decipher the contents. However, the information content, as delivered and described verbally, is coherent and useful. The initial download time is fairly long (can be several minutes). Example topics covered are - design and fabrication of sensors, how they work, about DNA and antigen/anti-body.
	Multiple Regression	Details
	Description: This site, which is part of an on-line master�s level course from Manchester Metropolitan University, provides a solid introduction to the use of multiple regression. The presentation is logical and thoughtful, beginning with a glossary of important terms and then taking the reader through a review of bivariate regression, a series of seven guidelines for multiple regression, and the implementation and interpretation of multiple regression. The site includes one worked example that, although biological in nature, is easily accessible to students of analytical chemistry. One limitation to the site is its reliance on Minitab for calculations, which may not be available to students. Users, however, should not have a difficult time reproducing the calculations using other software packages, such as SPSS or Excel. Prior knowledge of the basics of bivariate regression is assumed; thus, the site is most appropriate for advanced undergraduates and graduate students.
	NMR Spectroscopy Tutorial	Details
	Description: This is a straight forward elementary approach to proton and carbon NMR analysis targeted at students who are just at the most beginning stages of NMR spectroscopy, for example those in a first-semester organic chemistry course. There are some good descriptions of the most basic aspects of NMR spectroscopy such as coupling and some very simple structure problems to solve that are useful to students at the most introductory level of NMR spectroscopy.
	NMR animation	Details
	Description: This site has very nicely animated tutorials on NMR with sufficient depth to be useful to the non-NMR savvy. The animations are accompanied by short descriptions so that the processes displayed can be understood by the viewer. This site goes beyond just showing precession. There are nice animations showing the effect of different pulses, including composite pulses on the magnetization, the effects of magnetic gradient pulses to measure diffusion and do coherence pathway selection. Other aspects are less useful since they basically just present material that could be found in a book in an animated format. The site is useful for teaching in a lecture setting. Students will find the images appealing.
	NMR of Paramagnetic Proteins	Details
	Description: This site presents an overview of techniques used for structural elucidation of paramagnetic metalloproteins. In the first section experiments for detection and assignment such as COSY, TOCSY, HMQC, 1D NOE, NOE-NOSEY, superweft-NOESY, EXSY and deuterium labeling are discussed in terms of their application to paramagnetic proteins. The NOE-NOESY and superweft-NOESY experiments are of particular interest because of the way they take advantage of the relaxation differences between those protons near the metal center and those further away. The NOE-NOESY allows the mapping of connectivities between broad and hyperfine shifted signals and the signals in the diamagnetic region of the spectrum. The superweft-NOESY is used to enhance connectivities between fast relaxing protons. The remainder of this section focuses on the magnetic susceptibility tensor and its anisotropy and direction. The next section deals with converting the experimental observations into distance constraints for input into structure refinement software. A nice step-wise approach is described that results in relatively accurate structures of paramagnetic metalloproteins. The final section addresses the state of NMR of paramagnetic molecules at the time of publication and notes more recent applications of structural constraints derived from hyperfine coupling and the observation of partially oriented systems due to anisotropic magnetic susceptibility. This manuscript jumps head first into the topic at hand citing examples and discussing the application and peculiarities of the various experiments. This leads to a nice discussion of the various types of distance constraints based on hyperfine coupling (contact, pseudocontact and relaxation-based) their extraction from the data as well as the improvements each brings to structure refinement pertaining to location of the metal ion. The content is directed to the more advanced NMR user and would be suitable for an upper division or graduate level NMR class.
	NMR Spectroscopy	Details
	Description: This site contains web-based programs that allow the user to predict chemical shifts, spin-spin coupling patterns and NMR line shapes affected by dynamic chemical exchange. This site will be most useful for students with a good background in the fundamentals of NMR theory.
	NMR Spectroscopy - Theory	Details
	Description: This web site begins with a simple quantum description of NMR and proceeds to introduce resonance absorption, relaxation, chemical shifts, and scalar couplings. This site will be useful for advanced undergraduate students needing a description of NMR that is more detailed than that given in most introductory Organic texts.
	NMR Spectroscopy: Lab 8	Details
	Description: A complete NMR laboratory exercise from a set of fifteen (15) experiments in various topic areas developed for a physical chemistry laboratory at New Mexico State University. Excellent introductory material is provided, along with links to additional sources of information, including NMR tutorials. Pre-lab questions are presented along with detailed laboratory procedures. The two part experiment has students first measure proton spectra for a set of unknown substances and to match the spectra with the compound in a list provided, followed by a kinetics measurement. While the procedure is specific to Varian instruments, users should be able to easily modify the parameters to their own instrument. Site authorization is required to use some of the embedded links, but even without that access, this experiment should be of interest to instructors in both instrumental or physical chemistry.
	NMR tutorial	Details
	Description: The introduction to this site provides an entry-level introductions to NMR in a text + figures format. The site also contains two example structure elucidation problems using NMR. IR and MS data complete with hints and answers. Although the molecules are pretty simple, the examples do a good job of illustrating the structure elucidation process. The site also has data for 5 more complex structure determination problems.
	Optical Tweezers: Measuring Piconewton Forces	Details
	Description: This is a comprehensive reference article for optical tweezers technology. It outlines application of this technique in the piconewton force measurement for biological samples. The article includes principle of the technique, calibration, and examples of the use of this technique in one single article. The paper is easy to read, self-contained, and complete. It supplies a good mix of theory and application, with interesting descriptions involving measurements with RNA and DNA. One needs to have a basic background in physics and biology to understand the theory and applications. The article is written at the senior level for undergraduates as well as graduate students. The content is acceptable for ASDL.
	Optics Tutorial	Details
	Description: For those wishing to design optical instruments or understand why an optical instrument was designed a particular way, this site explains the engineering details in more depth than typical textbooks.
	Organic Chemistry On Line	Details
	Description: This site covers introductory material related to the analysis of small organic molecules by mass spectrometry, uv-visible spectrophotometry, IR spectrophotometry, and nmr spectroscopy. A concise explanation of each approach is presented with illustrations. This would be useful for those teaching organic chemistry and for others who need a review of the topic. It is treated from the standpoint of the phenomenon related to the measurement and the results one would obtain. It does not present much detail on the instrumentation. The section on Spectroscopy Resources at the end of the site contains a list of links to additional information plus a several links to compilations of problems (and their solutions) that challeng the student to interpret NMR or IR spectra.
	Organic Structure Elucidation Workbook	Details
	Description: This web site contains 64 structure elucidation problems for the qualitative analysis of organic compounds. For each problem the empirical formula, molecular weight, 500 MHz proton and 125 MHz carbon NMR spectra, IR and mass spectral data are presented. The problems are categorized as easy, moderate or difficult. Students in introductory Organic Chemistry who want practice identifying unknown compounds should find this site useful. Instructors looking for exam or classroom problems for students at this level could also take advantage of the information on this site.
	Origin of Chromatography	Details
	Description: This site has a series of links to QuickTime movies that animate the chromatographic process. The movies show the effect of changing K, L, and N on peak width and separation. The site is useful in combination with other sources that explain the background theory.
	Overview of Scanning Probe Microscopy Techniques	Details
	Description: This manufacturer's site offers a brief, readable, and well-illustrated introduction to several important methods in scanning probe microscopy (SPM), including STM, AFM, and NSOM. "Education links" include 3-d animations from surface scans utilizing these techniques. An excellent "Suggested Reading" section contains links to on-line texts and references to books covering SPM and other topics in nanoscience.
	Paper Chromatography	Details
	Description: This site is a very brief introduction to the idea of separation of components in a mixture and a set of instructions for students for separating colored compounds by paper chromatography (on coffee filters). The appropriate audience would be students in a high-school or introductory, non major's college chemistry class.
	Paper Chromatography of Dyes in Foods	Details
	Description: This site about paper chromatography is organized and the information is presented well -- perhaps making it one of the better sites about paper chromatography.
	Paper Chromatography of Stains	Details
	Description: A paper chromatography experiment separating dyes. The experiment is targeted toward 8-12 grades, but could be suited to an introductory chem laboratory section.The text of the site contains instructions for setting up and executing the experiment in a large class setting.
	PC Software for NMR, IR	Details
	Description: This web site allows readers to download a variety of PC-based NMR simulation programs. NMRSM is for the calculation of spin-spin coupling patterns, the program FTNMR Simulator simulates the operation of a high field spectrometer and the program FIDMAKER allows the user to create FID's for subsequent analysis by students. Although these simulation programs are fairly limited in their scope, they will be useful for faculty at institutions that do not have access to a modern Fourier transform NMR spectrometer.
	Photodetectors and Fiber Optics	Details
	Description: Power point slides to support a lecture on the principles and usage of photodiodes and optical fibers for sensors and instrumentation. There is no supporting text for the slides.
	Photodiode Technical Guide	Details
	Description: This website by Hamamatsu provides a fairly extensive presentation on the fundamentals and operational characteristics of a photodiode. One can learn about what governs the spectral response region, the gain characteristics and how to couple to an amplifier for the final output stage. It is an excellent primer for anyone wishes to learn about photodiodes.
	Pierce Biotechnology	Details
	Description: The pedagogical value lies in its concise description of the various analytical derivatization reactions and reagents used for gas chromatography. This site gives a nice description of the various derivatization reagents and what type of analyte they are used for. One of the few, if not the only, ASDL sites dealing with derivatization.
	PMT HandBook	Details
	Description: The commercial site is an extensive description of the fundamentals and applications of photomultipliers including their characteristics, structures, operating parameters, and applications areas. The contents are provided in 14 chapters covering 323 pages that include nearly everything that you ever wanted to know about photomultiplier tubes. Reading the text and accompanying illustrations with patience and care, you can become an expert on the subject. It will allow the practitioner to use this as a guide in not only understanding how a PMT works but moreover, have sufficient knowledge to built an instrument with the right selection of a specific PMT. Chapter 14 provides a wide range of illustrative applications, from a simple spectrophotometer to confocal microscopes to scanning electron microscopes to positron imagers. This is an excellent source of information for those interested in learning fundamentals and applications of instruments based on monitoring light or particles.
	Polymeric matrices for DNA sequencing by capillary electrophoresis	Details
	Description: This article reviews a variety of polymer types that have been used for both single and double stranded DNA separations. Comparisons are made in terms of the length of sequences that can be accurately read, the viscosity, ease of column filling, matrix stability, separation time and conditions for optimum resolution. These details are not likely available in another single source.
	Potentiometry	Details
	Description: This link contains a set of lecture notes with illustrations from the potentiometry section of CEM 333, Instrumental Analysis at Michigan State University. Topics include potentiometric electrodes and their underlying theory, along with useful hints in their application.
	Potentiostats	Details
	Description: This PDF document (52 pages) provides a comprehensive discussion of background history, theoretical considerations, electronic circuitry and design of potentiostats. Subject is treated in depth not found in textbooks, although computerized formats are not included.
	Principal Component Analysis	Details
	Description: This site, which is part of an on-line master�s level course from Manchester Metropolitan University, provides a solid introduction to principal component analysis. The presentation is logical and thoughtful, beginning with a glossary of important terms and then taking the reader through the process of completing a principal component analysis. Two particularly impressive parts of the site are the explanation of projecting higher dimension data to a lower dimension, and a graphical explanation of principal components. The site includes three worked example that, although biological in nature, are accessible to students of analytical chemistry. One limitation to the site is its reliance on Minitab and SPSS for calculations, which may not be available to students. Users without access to one of these programs will need access to another software package, such as the freeware program R. Prior knowledge of basic statistics is assumed; thus, the site is most appropriate for advanced undergraduates and graduate students.
	Principles of Scanning Probe Microscopy	Details
	Description: This site offers a beautifully illustrated introduction to the principles of scanning probe microscopy. The text is interspersed with links to additional information, much of it from the Interface Physics Group at Leiden University. There are several included animations and links to picture galleries which illustrate both principles and utilization of scanning probe microscopy. An additional "links" page takes the user to sites of research groups involved in ongoing developmental work in surface science.
	Quantitative NMR	Details
	Description: A learning module focused on principles and practice of NMR for quantitative analysis, an application less commonly associated with the technique than is structure determination. Links to simulation packages are included.
	Quantitative Spectroscopic Calibration	Details
	Description: Spectroscopic calibration is the process of using mathematical calculations to relate spectroscopic measurements to the chemical composition. Several algorithms can be used to perform these calculations. Success depends on selecting a suitable set of calibration samples to �train� the system, using the correct algorithm to match the characteristics of the measured data, and properly evaluating and validating the calibration model developed. Various aspects of calibrating spectroscopic instruments to perform quantitative analysis are discussed. The article ends with an overview of the various algorithms that are available to perform the calibration process.
	Radioanalytical Chemistry	Details
	Description: Course on the use of radionuclides in analytical chemistry. Types of radioactive decay are discussed as well as the techniques of scintillation counting, neutron activation analysis, and gamma spectroscopy.
	Receptor Binding Assays	Details
	Description: A great tutorial on receptor binding assays used in bioanalysis. Both scintillation proximity assays and measurements based on fluorescence polarization are discussed. This page also features a good bibliography on related resources.
	Redox Potentiometry	Details
	Description: This site contains materials from a lecture course in Biophysics, covering activity, free energy, equilibrium constants, and effect of pH on redox potentials, potentiometry, and reaction rates. The redox-specific content is based on interesting biological reactions not often found in chemistry texts.
	Reliable Measurements: A Guidebook for Trace Analysts	Details
	Description: Written by Dr. Paul Gaines from Inorganic Ventures, Inc., this website provides a comprehensive resource on sample preparation and analysis for those interested in elemental determinations by atomic spectrometry, especially ICP-OES and ICP-MS. Issues such as sources of contamination, detection limits, sample preparation, standard stability, and method validation are well covered on this website. An excellent set of references is also provided.
	Reverse Phase HPLC Basics for LC/MS	Details
	Description: This site provides a tutorial on practical reverse phase chromatography for LC-MS. Focusing on peptide and protein analysis, Andrew Guzzetta offers appropriate tips on mobile phase gradients, preparing your reversed-phase HPLC column for the first run of the day, and taking care of your column after the day's separations are complete. The site also provides a representative list of web-based resources on LC.
	Reversed phase column characteristics and general chrom. overview	Details
	Description: This is a link within the Waters HPLC Primer site. It contains very useful details regarding the properties of HPLC packing materials and how they impact performance. Since it is part of a larger site, it contains links to other information provided by waters on other aspects of HPLC as well as MS and other techniques. There is a higher level of detail in the instruction here than in most general sites discussing HPLC. Also, the site shows which Waters columns contain the different kinds of packing materials described, which would be helpful to a lot of people.
	Reversed Phase HPLC Mechanisms	Details
	Description: This is a Powerpoint Presentation on reversed phase mechanisms in HPLC. It includes a good but superficial discussion of reversed phase mechanisms and would expect the user to provide the depth. Instructors may find it helpful as an outline for a lecture on HPLC.
	Rheodyne - Application Support	Details
	Description: Application notes, technical information, and on-line trouble-shooting guide pertinent for Rheodyne products (high-pressure valves).
	RLM Synge Nobel Prize Lecture	Details
	Description: This site describes the applications of partition chromatography. The pedagogical value lies in its historical perspective and in its description of the early applications of partition chromatography. This site provided a unique historical perspective on the applications of partition chromatography and one of the pioneers of the technique. This document also contains many relevant figures and graphics.
	RSC.org: Gas Chromatography	Details
	Description: This video, distributed on YouTube by the Royal Society of Chemistry is on the basic principles of GC. This video is a short primer (~5 min) which introduces the technique and instrumentation. There are many assumptions that are made in the presentation of this material, due to the fact the video is meant to be a basic introduction. Examples of such assumptions include the statement that volatility solely controls the elution order of volatile compounds on a GC column and that concentration is the only parameter that controls the relative response of a compound for a given GC detector. The ultimate strength of this video is the general nature of the content that makes it appealing to a wide audience. The video may be most appropriate in a lower-level general education science course (i.e forensic science) or as a quick orientation video for instrumental analysis students. The GC-FID and GC-MS are highlighted.
	RSC.org: IR Spectroscopy	Details
	Description: This video, distributed on YouTube by the Royal Society of Chemistry is on the basic principles of infrared spectroscopy. This video is very useful for a newcomer to IR. The video highlights important basics to the technique. The "top-off" look of the instrument and use of a common real-life sample to demonstrate the instrument is quite useful. This site is a thorough primer at a basic level. The short video (6.5 min) would be useful in a classroom setting or students on their own interested in the technique.
	RSC.org: Mass Spectrometry	Details
	Description: This video, distributed on YouTube by the Royal Society of Chemistry is on the basic principles of mass spectrometry, using a magnetic sector instrument to demonstrate how specific m/z ratios can be selected. The theory and operation of MS, including the chemistry of ionization and fragmentation is described at an introductory level. There's also an excellent example of the use of high resolution MS to differentiate between nominal mass and actual mass. The video does a very good job of explaining the concept such that only a little background knowledge is required. The video is short enough (6 mins), that it would be very useful in a class setting or for students outside of class. The ultimate strength of this video is the general nature of the content that makes it appealing to a wide audience. The video may be most appropriate in a lower-level general education science course (i.e forensic science) or as a quick orientation video for instrumental analysis students prior to introducing mathematical or operational concepts. This video would also be helpful for a lay science person who wishes to learn more about mass spectrometry from a general interest perspective.
	RSC.org: UV/Vis Spectroscopy	Details
	Description: This video, distributed on YouTube by the Royal Society of Chemistry is on the basic principles of UV/Vis. This video is a good primer (~5 min) and the �top-off� look of the instrument is useful in explaining components. A double beam instrument is described in this video.
	Scanning Electrochemical Microscopy	Details
	Description: A concise synopsis of scanning electrochemical microscopy (SECM) with an extensive bibliography. Excellent color graphics and short animations are used effectively to demonstrate the instrumental essentials, physical aspects, and operational modes of SECM.
	Scanning Probe Microscopy	Details
	Description: Excellent web-resource on scanning probe microscopy accessible to beginners who wish to learn basics of these methods. Descriptions with figures and diagrams introduce atomic force microscopy (AFM), scanning tunneling microscopy (STM) and electrochemical scanning tunneling microscopy (EC-STM). The site also provides an overview of the variety of applications of these methods.
	Selerity Technologies Application Notes	Details
	Description: Applications and tutorials related to supercritical fluid chromatography and temperature programming in liquid chromatography (PDF). Application area is mainly petrochemicals.
	Separation Science Animations	Details
	Description: This site from TRSL is the main site that links to many animations related to how chromatography systems work. Most of the animations are quite good and would be helpful to students when trying to visualize what occurs in an instrument during a separation (e.g. injection, detection, etc.).
	SGE Chromatography Products - Troubleshooting and Training	Details
	Description: A guide to troubleshooting chromatography problems, especially GC. There is also material on increasing column efficiency and reference material on properties of stationary phases.
	SIMS Animation	Details
	Description: Watch simulations of atoms and molecules colliding with a metallic matrix. See crystal structures disrupted and atoms sputtered.
	Solid State NMR	Details
	Description: This Site provides an excellent treatment of solid state NMR, including MAS, cross polarization, multiple quantum coherence experiments and spectroscopy of quadrupolar nuclei, with many supporting figures. The presentation requires a solid understanding of the principles of NMR.
	SPECTROPHOTOMETRIC DETERMINATION OF ASCORBIC ACID IN ...	Details
	Description: This is an article describing the flow injection analysis of ascobic analysis using iron phenanthroline as a redox reagent with following UV vis detection. Although this paper is from the primary literature, the material is presented at a level that can be understood by undergraduates. It provides a good illustration of the factors affecting the quality of flow injection analysis and illustrates how a analytical method is optimized. The material is discussed in sufficient detail that a class could repeat the exercise or complete a problem set based on this article
	Spectroscopy	Details
	Description: This website describes the theory and practice of IR and NMR spectroscopy for classroom and laboratory instruction. Although it is written for a course at the University of Colorado, Boulder, this site is appropriate for anyone doing analytical measurements with infrared or NMR. Its contents is comprehensive with excellent and straightforward illustrations.The website incorporates several tutorials on IR and NMR theory. In addition, it presents sample energy calculations and both pdf and Powerpoint files that describe IR and NMR in detail. There are also links to spectral databases.
	Split Injection GC	Details
	Description: This site is one in a series of sites with very good animations related to separations. This animation deals specifically with split injection in gas chromatography. The animations are short (one to two minutes) and can easily be shown in class as part of a lecture. They are extremely helpful in illustrating key components and concepts of chromatographic systems. Users are encouraged to explore the site and the other brief animations as well. Separate links to other simulations by the same company (TRSL) are also listed on ASDL.
	SPR : Surface Plasmon Resonance Tutorial	Details
	Description: This website provides a straightforward introduction to the fundamentals of SPR, the genesis of the plasmon and the evanescent wave, and how SPR can be used to monitor the chemical nature of species adsorbed to the surface of a metal substrate. It provides a good tutorial on a subject just getting to the textbooks.
	SPR and Related Calculations	Details
	Description: Computation of Surface Plasmon Resonance using common surfaces (gold, silver, copper) and wavelengths (632.8 nm) is done on-line. The site is maintained for researchers and students alike.
	Study of Electrode Mechanism by Cyclic Voltammetry	Details
	Description: This lab experiment uses cyclic voltammetry to determine the concentration of acetaminophen (active ingredient of Tylenol) in a children’s pain relief elixir and to study the pH dependent mechanism of its oxidation. The experiment includes theory, pre-lab, write-up instructions and reference article.
	Surface Acoustic Wave/Gas Chromatography System for Trace Vapor Analysis	Details
	Description: A cost analysis and progress report to the Federal Government's Department of Energy detailing the use of a surface acoustic/wave gas chromatograph for trace vapor analysis. It contains a brief description of surface acoustic wave (SAW) detectors used with gas chromatography. This site is a good example of the detailed reports chemists and engineers might put together to obtain or continue to get funding.
	Surface Science Forum	Details
	Description: Extensive information about all forms of surface analysis including detailed information on analytical techniques, online tutorials, reference data, conference information, news and links to other resources.
	Surface Science Tutorials	Details
	Description: The Surface Analysis Forum contains tutorials, databases containing reference values important for many surface analyses, and a glossary for surface science technique acronyms. The tutorials are really on-line courses offered in specific aspects of surface analysis. All are presented in a clear fashion. In addition, there is a link to software (much of it free and downloadable) for data analysisThe site is structured for teaching and is easy to read.
	Synthesis of a Sonogel-Carbon Modified Sensor Electrode with Titanium Oxide (TiO2) to Detect Catechol	Details
	Description: This experiment demonstrates cyclic voltammetry, surface modification, selectivity, and bioanalysis in assaying catechols in the presence of ascorbic acid. Pre- or post-lab questions are included, along with sample student data and instructor’s notes.
	Teaching Chemical Equilibrium Concepts Using Field-Lab Experiences	Details
	Description: This online article describes an inquiry-based experience designed to integrate concepts in water quality and geology for pre-education science students preparing to become teachers at the primary and secondary level. The field and laboratory exercise could be used to effectively introduce equilibrium chemistry in an introductory or environmental chemistry course, and courses for non-majors.
	Terahertz radiation: applications and sources	Details
	Description: The site describes applications and basic instrumentation for terahertz spectroscopy. It contains an article that originally appeared in the American Institute of Physics publication The Industrial Physicist. Sources for terahertz spectroscopy and imaging applications are emphasized. A bibliography with suggestions for further reading is included.
	The Basics of MRI	Details
	Description: This web site is an on-line textbook describing the principles of magnetic resonance imaging (MRI). The treatment is often quite mathematical, but the site also reviews all of the mathematics and physics needed to understand the material. Approximately forty clinical images can also be found on the site. This site is appropriate for students needing a stand-alone introduction to MRI.
	The Fluoride Ion Selective Electrode Experiment	Details
	Description: This is an experiment for the determination of fluoride ion with an ion selective electrode (ISE). While some experimental guidelines are given, students are left to choose appropriate standard concentrations and sample type, and to develop their own experimental procedure.
	The History of Mass Spectrometry	Details
	Description: This site provides a brief history of the development of mass spectrometry. The works of Thompson and Aston are presented along with a brief overview of the modern evolution of mass spectrometry. This site will be useful for beginning students interested in a historical overview of the field of mass spectrometry. This is an archived version of the site.
	The HPLC Doctor	Details
	Description: This site provides HPLC troubleshooting tips. It covers common separation problems such as peak fronting or tailing and split peaks and suggests solutions. This site will be most useful for students and practitioners who already have some background knowledge of separation theory. It will be especially helpful for laboratory or research students who are developing a new separation method or are encountering problems with their chromatographic experiments.
	The Macrogalleria -- A Cyber Wonderland of Polymer Fun	Details
	Description: This site is devoted to analysis of polymers and focuses on SEC, although links to other techniques are provided. It does not go into great detail, but provides a nice overview of critical ideas behind SEC. The link to molecular weight distributions may alos help some students with the concepts behind polymers and polymer analysis. It is written simplistically and in an informal manner, which may put some people off, but others might enjoy it for this reason.
	The Practical Application of Light	Details
	Description: This commercial website is a good tutorial on optical design. While users should know a few freshman physics ideas about the nature of light and imaging, the novice optical designer can start from scratch using the material provided by Melles Griot.
	Understanding Chemistry	Details
	Description: This website part of a larger project "ChemGuide" provides a nice introduction to mass spectrometry that is suitable for use by introductory analytical chemistry students. Content includes an introduction to the instrumentation, explanation of fragmentation and how it can be used to identify compound structure, the origin of the M+ and (M+1)+ peaks. Each section is succinct, well written and provides a simple example. As such the site should be useful to faculty introducing mass spectrometry in the analytical classroom and to chemistry students.
	Understanding NMR	Details
	Description: This site provides links to a series of pdf files that represent chapters of an e-text on the basics of NMR. While many textbooks on NMR are available the chief merit of this one is that it has a nice chapter on the NMR instrument (ch. 5) which should be accessible to undergraduates. The text also provides a relatively mathematics-free or maybe more accurately Dirac bracket notation-free introduction to 1-D and 2-D (COSY and NOESY) experiments that would be appreciated by advanced undergraduates or beginning graduate students involved in undergraduate research experiences using NMR
	UV-visible spectroscopy	Details
	Description: This webpage, part of a larger project "Understanding Chemistry", provides a solid introduction to UV-vis spectroscopy suitable for use in introductory chemistry and introductory analytical chemistry courses. The UV-vis pages discuss UV-vis light, absorption, Beer's law, the double-beam spectrometer, and introduce some standard applications of UV-vis spectroscopy. Explication is clear and thoughtful. Judicious and effective use of graphics. Site is easy to navigate, and the links work. Some typos.
	Veeco Nanotheater	Details
	Description: Veeco's Nanotheater provides over 350 images of surfaces acquired using atomic force microscopy and scanning probe microscopy. Images come from a wide variety of samples, including polymers, biologicals such as bacteria, and inorganic crystals. Many of the images contains brief descriptions of what is being shown, although the information is not particularly in-depth. Additional information on atomic force microscopy and scanning probe microcopy, including useful guides and animations, is available using the link for "Library" at the top of the web site. The annotations with each image are limited. This site is best used in conjunction with outer sides on ASDL to explain scanning probe microscopy such as 10043 Introduction to Scanning Probe Microscopy.
	VMSL: Virtual Mass Spectrometry Laboratory	Details
	Description: This site presents a series of case studies that can be explored using modern mass spectrometry methods. The problem-solving nature of the site provides students a virtual laboratory experience that can supplement access to mass spectrometry instrumentation.
	Vydac Application Notes Online	Details
	Description: Short application notes and technical information pertinent for Vydac products. Application and trouble-shooting information for separations of peptides, proteins, oligionucleotides and carbohydrates using liquid and ion-exchange chromatography.
	WebSpectra - Problems in NMR and IR Spectroscopy	Details
	Description: This web site provides thirty beginning, twenty-nine intermediate, and sixteen advanced NMR structure analysis problems and their solutions. For every unknown a proton and a carbon spectrum are provided. Many of the more advanced problems contain COSY and DEPT spectra as well. A particularly useful feature of this site is that the user can zoom into spectral regions in all of the spectra.
	X-ray Diffraction	Details
	Description: This Site Is A Good Freshman Or Sophomore Level Introduction To Diffraction And Its Application To Studying Crystal Structure. Because It's Very Visual And Interactive, It Engages The Student. It's Not Mathematical Enough For An Upper Level Course. The basics of diffraction are covered with excellent interactive demos. Demos are great as a supplement but not as a stand alone module on diffraction.